Abstract: The disclosure provides a method and device for correction of the multi-channel capacitive sensor. The method includes: under calibrating mode, inputting the calibration signal from the calibration capacitance network module to the multi-channel capacitive sensor, and measuring the output complex voltage at each calibration frequency point; selecting any channel as a reference channel, combining each-channel three-admittance parameters with the output complex voltages at each calibration frequency point, calculating each-channel amplitude-phase correction coefficient relative to the reference channel; under operating mode, inputting a carrier signal to the multi-channel capacitive sensor through the multiple DoF sensitive probe, and measuring the output complex voltages under actual operation; and multiplying the output complex voltages by the correction coefficients, thereby obtaining the multiple sensing channel output signals.

Abstract: The present disclosure provides a bone conduction-based clamping device and processing method. The device includes a handle, a clamping structure provided on one side of the handle, and a sound generating processor provided inside the handle. A user puts food into his mouth cavity by clamping the food with the clamping structure, and a vibration signal generated by the sound generating processor is transmitted to the food by the clamping structure and then transmitted to the user's auditory system by an oral tissue or teeth of the user, thereby avoiding the pressing feeling caused by wearing in a pressing manner. Putting the clamping structure into the user's mouth cavity can also reduce sound leakage, improve sound quality and protect privacy. In addition, the food can be replaced by the clamping structure, thereby guaranteeing hygiene and health, improving the usage rate of the device, and realizing multi-user sharing.

Abstract: The present disclosure provides a bone conduction based sound generating lollipop, a processing method and a system thereto. The bone conduction based sound generating lollipop includes a housing, a trigger, a controller and a sound generating component. The sound generating component, the controller and the trigger are integrated in a packaging cavity formed by the housing, and a separate packaging of the sound generating component is eliminated. When a supporting component of the housing enters a human oral cavity, the trigger sends an opening instruction to the controller, the controller drives the sound generating component to vibrate, and then a vibration signal is transmitted to a human auditory system in a bone conduction manner after passing through the supporting component of the housing and an edible object attached to the supporting component, and passing through an oral tissue or teeth of the human body.

Abstract: A semiconductor structure includes a substrate and a first bit line pillar. The first bit line pillar is located on the substrate, and includes a first dielectric layer, a first insulating layer, and a first contact layer that are successively stacked in a thickness direction of the substrate. The first insulating layer is adjacent to the substrate and has a first preset thickness. The first preset thickness is associated with a thickness sum of the first dielectric layer, the first insulating layer, and the first contact layer. A ratio of a length of a top surface of the first insulating layer in a first direction to a length of a bottom surface of the first insulating layer in the first direction is a first target value. The first direction, the top surface and the bottom surface of the first insulating layer are all perpendicular to the thickness direction.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN 1 is driven by a native SMN 1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: Methods, systems, and devices for analyzing a sample for the presence of a target protein are provided. A sample can be processed, the processing generating an amplification product of a template nucleic acid formed in response to a target protein being present in the sample. The amplification product can be contacted with a detection probe to generate a second product comprising a labeled nucleic acid. A lateral flow substrate can be contacted with the second product, the lateral flow substrate comprising a capture moiety configured to bind the labeled nucleic acid. The methods can be carried out in one or more chambers of a single device or multiple devices. Detection probe bound to amplicons of the template nucleic acid captured on the lateral flow substrate can be read visually or using a sensor.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN1 is driven by a native SMN1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: A photonic integrated circuit structure comprises a first photonic chip module, having a first upper side and a first lower side substantially parallel to the first upper side; a second photonic chip module, having a second upper side and a second lower side substantially parallel to the second upper side, the second upper side integrally connected to the first lower side; and a predetermined cropping area, located between the second upper side and the first lower side, configured to be a reference when block cropping is performed. The photonic integrated circuit structure may be applied to photonic chip usage specifications of 4-channel transmission or 8-channel transmission.

Abstract: A light receiving and emitting module includes a sub-mount platform, a photoelectrical conversion component, a lens and a base. The sub-mount platform is made of silicon-based material and has first and second contact surfaces. The photoelectrical conversion component is disposed on the first contact surface. The lens is disposed on the second contact surface. The sub-mount platform is disposed on one side of the base. The first contact surface and second contact surface have therebetween a height difference, such that the photoelectrical conversion component matches the center of the lens. Further provided is a light receiving and emitting device including the light receiving and emitting module, a printed circuit board and a plurality of conducting wires. The conducting wires are electrically connected to the photoelectrical conversion component and printed circuit board. The conducting wires are disposed on at least two sides of the light receiving and emitting module.

Abstract: A method for correcting space coordinates of a three-dimensional model includes: step S1, reading information of an original coordinate frame of a three-dimensional model in a first format and the origin of coordinates of the model; reading information of nodes from three-dimensional model data in the first format, and calculating original coordinates of the nodes; step S2, calculating parameters of correction between the original coordinate frame and a target coordinate frame; step S3, transforming and correcting the coordinates of the origin and nodes of the three-dimensional model in the first format one by one by using the space coordinate correction matrix to obtain information of coordinate points of the three-dimensional model in the second format; and step S4, storing a file of the three-dimensional model in the second format with corrected space coordinates. Also, a method for encrypting space coordinates of a three-dimensional model is provided.

Abstract: An apparatus, a method and a system. The apparatus comprises a memory array including word lines defining a staircase structure, and a staircase etch stop layer including: a sandwich etch stop layer disposed on a top region the staircase and including a first etch stop layer and a third etch stop layer of a first material, and a second etch stop layer sandwiched between the first etch stop layer and the third etch stop layer and made of a second material having etch properties different from the first material; a precut etch stop layer disposed at a region of the staircase structure below the top region and including the second etch stop layer and the third etch stop layer and not the first etch stop layer; and contact structures extending through a dielectric layer and the staircase etch stop layer and landing on the word lines at the staircase structure.

Abstract: The present disclosure provides a bone conduction based sound generating lollipop, a processing method and a system thereto. The bone conduction based sound generating lollipop includes a housing, a trigger, a controller and a sound generating component. The sound generating component, the controller and the trigger are integrated in a packaging cavity formed by the housing, and a separate packaging of the sound generating component is eliminated. When a supporting component of the housing enters a human oral cavity, the trigger sends an opening instruction to the controller, the controller drives the sound generating component to vibrate, and then a vibration signal is transmitted to a human auditory system in a bone conduction manner after passing through the supporting component of the housing and an edible object attached to the supporting component, and passing through an oral tissue or teeth of the human body.

Abstract: The present disclosure provides a bone conduction-based clamping device and processing method. The device includes a handle, a clamping structure provided on one side of the handle, and a sound generating processor provided inside the handle. A user puts food into his mouth cavity by clamping the food with the clamping structure, and a vibration signal generated by the sound generating processor is transmitted to the food by the clamping structure and then transmitted to the user’s auditory system by an oral tissue or teeth of the user, thereby avoiding the pressing feeling caused by wearing in a pressing manner. Putting the clamping structure into the user’s mouth cavity can also reduce sound leakage, improve sound quality and protect privacy. In addition, the food can be replaced by the clamping structure, thereby guaranteeing hygiene and health, improving the usage rate of the device, and realizing multi-user sharing.

Abstract: A method of estimating employee turnover rates obtains original employee data from a preset data source. First data processing is applied to the original employee data to obtain first processed employee data. A training set and a first verification set are selected from the first processed employee data. The training set is used to train a machine learning model to obtain a turnover estimation model. The first verification set is used to verify the turnover estimation model to obtain a first estimation result. The turnover estimation model is optimized according to the first estimation result to obtain an optimized turnover estimation model. Updated employee data and a corresponding employee turnover rate of a second time period are obtained. The method helps to replenish manpower in time and avoids over-recruitment.

Abstract: The present disclosure provides a method for correcting and encrypting space coordinates of a three-dimensional model.

Abstract: A memory device with a three-dimensional (3D) staircase memory stack includes dummy connectors proximate semi-isolated connectors. The memory device includes multiple wordlines stacked in a 3D staircase stack, which includes a wordline at an edge of a region of the staircase. The memory device includes vertical connectors through an isolation layer on the 3D staircase stack to connect the wordlines with conductive lines in an access layer. A wordline at the edge of the region of the staircase has a vertical connector that will be adjacent a connector on one side and not on the other side. The memory device includes at least one dummy vertical connector on the edge side of the vertical connector of the wordline on the edge, wherein the dummy vertical connector does not electrically connect a wordline of the 3D staircase stack to a conductive line in the access layer.

Abstract: Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase (“COX”)-1, COX-2, and 5-lipoxygenase (“5-LOX”). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents.

Abstract: A light receiving and emitting module includes a sub-mount platform, a photoelectrical conversion component, a lens and a base. The sub-mount platform is made of silicon-based material and has first and second contact surfaces. The photoelectrical conversion component is disposed on the first contact surface. The lens is disposed on the second contact surface. The sub-mount platform is disposed on one side of the base. The first contact surface and second contact surface have therebetween a height difference, such that the photoelectrical conversion component matches the center of the lens. Further provided is a light receiving and emitting device including the light receiving and emitting module, a printed circuit board and a plurality of conducting wires. The conducting wires are electrically connected to the photoelectrical conversion component and printed circuit board. The conducting wires are disposed on at least two sides of the light receiving and emitting module.

Abstract: A terminal portion structure of an optical transmission element includes a light guiding component, glass protection layer and convex lens. The light guiding component includes a core and a cladding enclosing the core. The cladding is of a lower refractive index than the core, allowing light signals to be transmitted in the light guiding component by total internal reflection. The glass protection layer covers at least a terminal portion of the light guiding component. The convex lens is disposed on one side of the glass protection layer. The cross section of the terminal portion of the light guiding component tilts relative to the axial direction of the light guiding component. The optical axis of the convex lens is perpendicular to the axial direction of the light guiding component. The focal point of the convex lens is located at the cross section of the terminal portion of the core.

Abstract: Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase (“COX”)-1, COX-2, and 5-lipoxygenase (“5-LOX”). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents.