Patents by Inventor Hong Ngoc Thi Dang

Hong Ngoc Thi Dang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11857931
    Abstract: The application refers to process for production of a nano-microemulsion system of plant oil triglycerides, including: (i) preparing a dispersed phase plant oil triglyceride; (ii) preparing a carrier made from a mixture of propylene glycol monocaprylate and lecithin by a weight ratio of 5-6:1-1.5; (iii) adding the carrier to the dispersed phase by a weight ratio of 3-4:1-1.5, wherein the dispersed phase temperature is maintained between 60-100° C. while stirring under vacuum, followed by introduction of the whole mixture through the high-pressure microjet homogenizer; (iv) adding Tween 80 and Tween 60 to the solution mixture obtained in step (iii) by a weight ratio of 3-4:1-1.5:1-1.5, wherein the temperature of the dispersed phase is continuously maintained between 60-100° C.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: January 2, 2024
    Assignee: Wakamono Joint Stock Company
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Patent number: 11674107
    Abstract: The invention relates to the process for producing an microemulsion system of nano essential oil, the process comprising the following steps: (i) preparing a dispersed phase of essential oil; (ii) preparing of a carrier formed from a mixture of diethylene glycol monoethyl ether and lecithin; (iii) adding the carrier to the dispersed phase while keeping the dispersed phase temperature between 60 and 100° C. after addition of the carrier, while simultaneously stirring under vacuum; then pass the entire solution mixture through the system of high-pressure homogeneous machine integrated dispersion nozzle; (iv) adding the solution mixture obtained in step (iii) to Capryol 90 while keeping the mixture temperature between 60 and 100° C., and stirring at a rate ranging from 400 up to 800 rpm under vacuum; (v) cooling the mixture, homogenizing the mixture by ultrasonication to achieve a droplet size smaller than 100 nm.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: June 13, 2023
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Patent number: 11583498
    Abstract: The invention relates to a process for producing a Tan IIA nanoliposome system for foods and medical products, comprises: (i) preparing a dispersed phase by dissolving Tan IIA in ethanol in a Tan IIA weight:ethanol volume ratio of 8:10 by a stirrer at 300-500 rpm with heating to 40-60° C. within 4-8 hours; (ii) preparing a liposome carrier consisting of lecithin and olive oil in a ratio of 1:3 by weight by mixing in a constant temperature bath at 40-60° C. to ensure that lecithin is completely dissolved in the oil while stirring; (iii) adding the carrier to the dispersed phase in a ratio of 40:60 by weight, further heating the carrier and dispersed phase mixture to 40-60° C. and stirring at 800-1000 rpm within 1 to 2 hours; (iv) cooling the resulting mixture to 25° C. and pumping the cooled mixture, using an ultrasonic atomizer nozzle at 60 Hz (10-20 ?m droplet size, 10 mL/min), into 1-1.5 L of distilled water (with the temperature of the distilled water at 25° C.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: February 21, 2023
    Assignee: WAKAMONO CORPORATION
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Patent number: 11465107
    Abstract: The present invention relates to a process of producing a nano Omega-3 microemulsion system includes: (i) preparing a dispersal phase by heating Omega-3; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol); (iii) adding the carrier to the dispersal phase; (iv) emulsifying as follows: when the temperature arrives at 60° C., adding ACRYSOL K-140 to the mixture of the carrier and dispersal phase in step (iii), continuing to stir at a speed of 500 to 700 rpm, at a temperature of 60 to 80° C., in vacuum, for 3 to 5 hours, controlling the quality of resulting product by dissolving into water and measuring the transparency, the reaction is quenched, the temperature is decreased slowly until it is in the range of 40 to 60° C.; emulsifying for the entire mixture for 30 minutes; (v) filtrating the product by injecting through nanofilter system before filling-packaging.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: October 11, 2022
    Inventor: Hong Ngoc Thi Dang
  • Publication number: 20210277325
    Abstract: The invention relates to the process for producing an microemulsion system of nano essential oil, the process comprising the following steps: (i) preparing a dispersed phase of essential oil; (ii) preparing of a carrier formed from a mixture of diethylene glycol monoethyl ether and lecithin; (iii) adding the carrier to the dispersed phase while keeping the dispersed phase temperature between 60 and 100° C. after addition of the carrier, while simultaneously stirring under vacuum; then pass the entire solution mixture through the system of high-pressure homogeneous machine integrated dispersion nozzle; (iv) adding the solution mixture obtained in step (iii) to Capryol 90 while keeping the mixture temperature between 60 and 100° C., and stirring at a rate ranging from 400 up to 800 rpm under vacuum; (v) cooling the mixture, homogenizing the mixture by ultrasonication to achieve a droplet size smaller than 100 n.
    Type: Application
    Filed: March 31, 2020
    Publication date: September 9, 2021
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Publication number: 20210205220
    Abstract: The invention relates to a process for producing a Tan IIA nanoliposome system for foods and medical products, comprises: (i) preparing a dispersed phase by dissolving Tan IIA in ethanol in a Tan IIA weight:ethanol volume ratio of 8:10 by a stirrer at 300-500 rpm with heating to 40-60° C. within 4-8 hours; (ii) preparing a liposome carrier consisting of lecithin and olive oil in a ratio of 1:3 by weight by mixing in a constant temperature bath at 40-60° C. to ensure that lecithin is completely dissolved in the oil while stirring; (iii) adding the carrier to the dispersed phase in a ratio of 40:60 by weight, further heating the carrier and dispersed phase mixture to 40-60° C. and stirring at 800-1000 rpm within 1 to 2 hours; (iv) cooling the resulting mixture to 25° C. and pumping the cooled mixture, using an ultrasonic atomizer nozzle at 60 Hz (10-20 ?m droplet size, 10 mL/min), into 1-1.5 L of distilled water (with the temperature of the distilled water at 25° C.
    Type: Application
    Filed: December 18, 2020
    Publication date: July 8, 2021
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Patent number: 10882012
    Abstract: The present invention relates to a process of producing a nano resveratrol microemulsion system includes: (i) preparing a dispersal phase by dissolving resveratrol in an ethanol solvent; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) accounted from 40 to 60% by mass of the mixture of PEG and water to a temperature ranging from 60 to 80° C., then adding zeolite catalyst (0.1-0.4% by mass of mixture of PEG and water), stirring evenly; (iii) adding the carrier to the dispersal phase (in a ratio by mass of 40:60), continuing heating the said dispersal phase to 100° C., stirring at a speed of 400 to 800 rpm; (iv) elmusifying as follows: when the temperature arrives at 100° C., adding Tween to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 40:60, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 100° C. to 130° C.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 5, 2021
    Assignee: WAKAMONO CORPORATION
    Inventor: Hong Ngoc Thi Dang
  • Publication number: 20200346174
    Abstract: The application refers to process for production of a nano-microemulsion system of plant oil triglycerides, including: (i) preparing a dispersed phase plant oil triglyceride; (ii) preparing a carrier made from a mixture of propylene glycol monocaprylate and lecithin by a weight ratio of 5-6:1-1.5; (iii) adding the carrier to the dispersed phase by a weight ratio of 3-4:1-1.5, wherein the dispersed phase temperature is maintained between 60-100° C. while stirring under vacuum, followed by introduction of the whole mixture through the high-pressure microjet homogenizer; (iv) adding Tween 80 and Tween 60 to the solution mixture obtained in step (iii) by a weight ratio of 3-4:1-1.5:1-1.5, wherein the temperature of the dispersed phase is continuously maintained between 60-100° C.
    Type: Application
    Filed: July 16, 2020
    Publication date: November 5, 2020
    Inventors: Hong Ngoc Thi Dang, Nam Hai Lai
  • Publication number: 20190351378
    Abstract: The present invention relates to a process of producing a nano Omega-3 microemulsion system includes: (i) preparing a dispersal phase by heating Omega-3 to a temperature from 40 to 60° C.; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) to a temperature ranging from 40 to 60° C., stirring evenly; (iii) adding the carrier to the dispersal phase in a ratio by mass of 3:1, continuing to keep the said dispersal phase at a temperature ranging from 40 to 60° C., stirring at a speed of 400 to 800 rpm in vacuum; (iv) emulsifying as follows: when the temperature arrives at 60° C., adding ACRYSOL K-140 to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 6:4, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 60 to 80° C., in vacuum, the reaction temperature is kept at a temperature ranging from 60 to 80° C.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Applicant: WAKAMONO CORPORATION
    Inventor: Hong Ngoc Thi Dang
  • Publication number: 20190336922
    Abstract: The present invention relates to a process of producing a nano resveratrol microemulsion system includes: (i) preparing a dispersal phase by dissolving resveratrol in an ethanol solvent; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) accounted from 40 to 60% by mass of the mixture of PEG and water to a temperature ranging from 60 to 80° C., then adding zeolite catalyst (0.1-0.4% by mass of mixture of PEG and water), stirring evenly; (iii) adding the carrier to the dispersal phase (in a ratio by mass of 40:60), continuing heating the said dispersal phase to 100° C., stirring at a speed of 400 to 800 rpm; (iv) elmusifying as follows: when the temperature arrives at 100° C., adding Tween to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 40:60, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 100° C. to 130° C.
    Type: Application
    Filed: July 8, 2019
    Publication date: November 7, 2019
    Applicant: WAKAMONO CORPORATION
    Inventor: Hong Ngoc Thi Dang