Abstract: A self-balancing line shaft of a machine tool includes a spindle device, a cutter tool holder and at least one balancing assembly. The spindle device includes a spindle extending along and rotatable about an axis, and at least one precision lock nut threadedly engaged with and rotated with the spindle. The cutter tool holder is coaxially connected and rotated with the spindle. The balancing assembly includes an annular groove formed in one of the precision lock nut and the cutter tool holder and extending along a circle path surrounding the axis, and a plurality of weight members disposed in the annular groove to be moved in a direction opposite to a rotation unbalance during rotation of the spindle such that the center of mass of the whole rotating system is close to the axis.

Abstract: In a data transmission process of a heterogeneous LWA network, the base station device receives a series of data packets and a signal intensity information. A communication address of each of the series of data packet is directed to a specified user mobile device, and the signal intensity information indicates an intensity of a signal transmitted between the specified user mobile device and a wireless network access point device in communication with the base station device and the specified user mobile device. If the signal intensity information complies with a first specific condition and a status of data transmission associated with the user mobile device complies with a second specific condition, partial data packets are assigned to be transferred to the user mobile device by the wireless network access point device, and partial data packets are assigned to be transferred to the user mobile device by the base station device.

Abstract: A cutting device includes a housing formed with a handle portion and an accommodation portion, a cutting portion connected to the housing and at least partially disposed in the accommodation portion, a motor disposed in the accommodation portion and extending in a first linear direction, and a bottom plate extending in a plane of the bottom plate and formed with an opening through which at least part of the cutting portion passes. The cutting device further includes a worm gear and worm structure disposed in the accommodation portion. The cutting portion includes a chain and a guide plate connected to the housing and used for supporting the chain. The motor includes an output shaft, the cutting portion is connected to a driving shaft, the output shaft transmits power to the driving shaft through a worm gear and a worm, and the driving shaft is capable of driving the chain.

Abstract: The present application provides a compound of Formula (I) as an inhibitor against wild-type EGFR and/or mutant EGFR, which may be used for treating human non-small cell lung cancer individually or in combination with other therapeutic agent(s). The compound of Formula (I) of the present application may be used for treating patients of drug-resistant human non-small cell lung cancer harboring wild-type EGFR and/or EGFR T790M mutation and/or EGFR L858R mutation and/or EGFR delE746_A750 mutation.

Abstract: An oxidizing gas detection method and an apparatus thereof are provided for trace oxidizing gas detection. The detection method includes the following steps. First, perform an electroreduction reaction and a photoreduction reaction simultaneously to a metal oxide in which nanoconductors are distributed. Next, stop the electroreduction reaction and the photoreduction reaction, and read a resistance of the reduced metal oxide by applying a first pulse-width modulation signal. Next, provide an oxidizing gas to the reduced metal oxide, and photo-catalyze a redox reaction between the oxidizing gas and the reduced metal oxide. Next, read a resistance of the oxidized metal oxide by applying a second pulse-width modulation signal. Next, converse a concentration of the oxidizing gas according to a ratio of the resistance of the oxidized metal oxide and the resistance of the reduced metal oxide.

Abstract: Pharmaceutical compositions containing a combination of rhizoma coptidis and a herbal composition comprises at least one herb selected from the group consisting of Radix Ginseng, Poria, Rhizoma Atractylodis macrocephalae, Semen Lablab album, Rhizoma Dioscoreae, Embryo Nelumbinis, Radix Platycodonis, Semen Coicis, Fructus Amomi, Fructus Jujubae and Radix Glycyrrhizae are disclosed. Methods of treating diseases by administering an effective amount of the pharmaceutical composition are also provided.

Abstract: A filtering circuit for filtering a pulse width modulated (PWM) signal includes a D flip-flop having an input terminal configured to be coupled to a logic high signal and having an output terminal coupled to an output terminal of the filtering circuit; and a circuit coupled between an input terminal of the filtering circuit and the D flip-flop, the circuit configured to, for a first pulse of the PWM signal having a duty cycle within a pre-determined range: generate a positive pulse at a clock terminal of the D flip-flop as a clock signal of the D flip-flop; and generate a negative pulse at a reset terminal of the D flip-flop as a reset signal of the D flip-flop, wherein a duration between a rising edge of the positive pulse and a falling edge of the negative pulse is equal to a duration of the first pulse of the PWM signal.

Abstract: A polymeric composition comprising (i) a plurality of monomers selected from (a) a carboxylic acryloyi monomer; (b) a sulfonic acryloyi monomer; (c) an amine acryloyi monomer; (d) a hydroxyl acryloyi monomer; (e) an alkyl acryloyi monomer; and (f) a polyalkylene hydroxyl acryloyi monomer; (ii) a divalent metallic crosslinking agent; and (c) a stabilizing agent is disclosed herein. Also provided are the use of said polymeric composition as a hydrogel coating material, a method of synthesizing the polymeric composition and the use of the hydrogel material.

Abstract: An electronic device includes an energy storage unit, a charge pump circuit, a charging circuit, and a controller. The charge pump circuit is electrically connected to the power supply, and the power supply is configured to receive the input electrical energy. The charging circuit is electrically connected between the charge pump circuit and the energy storage unit. The controller is electrically connected with the power supply, the charge pump circuit, and the charging circuit respectively, and the controller controls the charge pump circuit and the charging circuit to switch among a plurality of charging modes according to compatibility information of the power supply.

Abstract: The invention provides a pH-sensitive linker that can simultaneously bind metallic nanoparticles and one or more agents with various molecular size. The linker of the invention can deliver the agents into cells involved in disease processes or close to cells so that the agents can selectively target and effect on the cells. The target delivery provided by the linker of the invention can be used for example for disease sensing, imaging, drug delivery, and therapy.

Abstract: A power module may be attached to and detached from a network extender. The power module may include one or more power connectors that are specific to one or more countries/regions. The power module may include one or more other interfaces (e.g., Ethernet port, etc.). The power module may include a power connector and a male local area network connector on a first surface. The power module may include a local area network port on a second surface, wherein the local area network port is conductively connected to the male local area network connector via a local area network port access.

Abstract: The present invention provides an inhibitor of Bruton's tyrosine kinase, which is a compound of formula (I), or its pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug. The present invention also provides a pharmaceutical composition comprising the compound. The present invention also provides a method for inhibiting the activity of tyrosine kinase activity or for treating a disease, disorder, or condition, which would benefit from the inhibition of Bruton's tyrosine kinase(s), by using the Bruton's tyrosine kinase inhibitor, as well application of the Bruton's tyrosine kinase inhibitor for the same.

Abstract: In a data transmission process of a heterogeneous LWA network, the base station device receives a series of data packets and a signal intensity information. A communication address of each of the series of data packet is directed to a specified user mobile device, and the signal intensity information indicates an intensity of a signal transmitted between the specified user mobile device and a wireless network access point device in communication with the base station device and the specified user mobile device. If the signal intensity information complies with a first specific condition and a status of data transmission associated with the user mobile device complies with a second specific condition, partial data packets are assigned to be transferred to the user mobile device by the wireless network access point device, and partial data packets are assigned to be transferred to the user mobile device by the base station device.

Abstract: A power supply device includes a PF correction circuit, a power switching circuit and a control circuit. The PF correction circuit converts an input voltage to a bus voltage according to a control signal to supply a later stage circuit. The power switching circuit selectively switches to conduct a first source or a second source to the PF correction circuit to provide the input voltage to the PF correction circuit. The control circuit outputs the control signal to the PF correction circuit. When the control circuit detects a first voltage of the first source connecting to the PF correction circuit is abnormal, the control circuit determines whether a second voltage of the second source is smaller than the bus voltage and controls the power switching circuit to switch when the second voltage is smaller than the bus voltage to conduct the second source to the PF correction circuit.

Abstract: A method of generating recommendations based on predicted activity external to a first region includes segmenting a plurality of users into at least a first subset of users and a second subset of users. The method also includes generating an activation metric for each user of the first and second subset of users. The method also includes determining a plurality of target users from the plurality of users. The method also includes automatically initiating a target action for each target user. A system and computer program product for generating recommendations based on predicted activity external to a first region is also disclosed.

Abstract: Various embodiments of the present disclosure are directed towards a method for forming a fully silicided (FUSI) gated device, the method including: forming a masking layer onto a gate structure over a substrate, the gate structure comprising a polysilicon layer. Forming a first source region and a first drain region on opposing sides of the gate structure within the substrate, the gate structure is formed before the first source and drain regions. Performing a first removal process to remove a portion of the masking layer and expose an upper surface of the polysilicon layer. The first source and drain regions are formed before the first removal process. Forming a conductive layer directly contacting the upper surface of the polysilicon layer. The conductive layer is formed after the first removal process. Converting the conductive layer and polysilicon layer into a FUSI layer. The FUSI layer is thin and uniform in thickness.

Abstract: Disclosed are compounds of Formula (I) Formula (I) or salts thereof, wherein HET is a heteroaryl selected from oxazolyl, pyrazolyl, imidazo[1,2-b]pyridazin-3-yl, and pyrazolo[1,5-a]pyrimidin-3-yl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a carbon ring atom in the heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; and R1, R3, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.

Abstract: An allocation method of communication resources is use with at least a user mobile device, at least first and second wireless network access point devices, and a base station device for mobile communication. In the allocation method, the base station device receives a registration request from the user mobile device; and the base station device determines an order of the first and second wireless network access point devices for the user mobile device to register in according to intensities of signals of the first and second wireless network access point devices, which are measured by the user mobile device, and counts of user mobile devices having registered in the first and second wireless network access point devices, respectively.

Abstract: A power module may be attached to and detached from a network extender. The power module may include one or more power connectors that are specific to one or more countries/regions. The power module may include one or more other interfaces (e.g., Ethernet port, etc.). The power module may include a power connector and a male local area network connector on a first surface. The power module may include a local area network port on a second surface, wherein the local area network port is conductively connected to the male local area network connector via a local area network port access.

Abstract: A charging circuit applied to a post-stage circuit includes a power converting circuit, a power storage circuit, a switching circuit and a processing circuit. The power converting circuit receives an external voltage and converts the external voltage to a charging voltage. The power storage circuit is coupled to the power converting circuit and receives the charging voltage to store the power. The switching circuit is coupled to the power converting circuit and the power storage circuit. The processing circuit is coupled to the switching circuit and controls the charging circuit operated in a first mode or a second mode. When operated in the first mode, the external voltage supplies power to the post-stage circuit. When operated in the second mode, the charging voltage supplies power to the post-stage circuit.