Patents by Inventor Hong-Xi Xu

Hong-Xi Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160303069
    Abstract: The present invention provides compound extracted from Garcinia species and the use of said compound in preventing and treating cancer.
    Type: Application
    Filed: April 15, 2016
    Publication date: October 20, 2016
    Inventors: Hong-xi XU, Yuan-zhi LAO, Zhi-jie DING, Hong ZHANG, Kai-xian CHEN, Hong-sheng TAN, Zhao-xiang BIAN, Cheng-yuan LIN, Shi-lin CHEN, Da-jian YANG, Ai-ping LU, Albert Sun Chi CHAN
  • Patent number: 9468623
    Abstract: The present invention provides compound extracted from Garcinia species and the use of said compound in preventing and treating cancer.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: October 18, 2016
    Assignee: Hong Kong Baptist University
    Inventors: Hong-xi Xu, Yuan-zhi Lao, Zhi-jie Ding, Hong Zhang, Kai-xian Chen, Hong-sheng Tan, Zhao-xiang Bian, Cheng-yuan Lin, Shi-lin Chen, Da-jian Yang, Ai-ping Lu, Albert Sun Chi Chan
  • Publication number: 20110301236
    Abstract: A novel compound isolated from the plant Garcinia paucinervis. The compound's structure is as follows: The compound possesses a potent ability to activate caspase-3 in HeLa-C3 cells within 72 h at a low concentration of 25 ?M. The IC50 on HeLa cells for this compound was measured to be below 10 ?M, indicating a strong HeLa cell growth inhibitory effect.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 8, 2011
    Inventors: XUE-MEI GAO, Ting Yu, Kathy Qian Luo, Hong Xi Xu
  • Publication number: 20110301233
    Abstract: Novel polyisoprenylated benzophenone derivatives isolated from the plant Garcinia paucinervis. Among these new compounds, paucinones A-C (Compounds 1-3) contains an unexpected cyclohexane-spiro-tetrahydrofuran moiety. A 1-methylene-3,3-dimethylcyclohexane group never reported before was found in the structure of paucinone D (Compound 4). Structures of these compounds were elucidated with spectroscopic evidence. The relative stereochemistry of 1-4 was determined by NOESY correlations. These compounds a potent ability to activate caspase-3 in HeLa-C3 cells within 72 hours at a low concentration and significant cytotoxicity against HeLa-C3 cells.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 8, 2011
    Inventors: XUE-MEI GAO, Ting Yu, Kathy Qian Luo, Hong Xi Xu
  • Publication number: 20100326720
    Abstract: A housing comprise a decorative layer including a transparent base, a first conductive coating, an electrically conductive ink layer having a first electrical interface and a second conductive coating having a second electrical interface. The first conductive coating is formed on the base, the electrically conductive ink layer is laminated with and covers the first conductive coating, the second conductive coating is laminated between the electrically conductive ink layer and the outer surface of the substrate, the first electrical interface of the first conductive coating and the second electrical interface of the second conductive coating are electrically connected to a power source for creating an electrical field between the first conductive coating and the second conductive layer to make the electrically conductive ink layer present a pattern.
    Type: Application
    Filed: April 9, 2010
    Publication date: December 30, 2010
    Applicants: SHENZHEN FUTAIHONG PRECISION INDUSTRY CO., LTD., FIH (HONG KONG) LIMITED
    Inventors: BEN-DING TSAO, WEN-LIN XIONG, DIAN-MING ZHU, JIANG-YING HU, HONG-XI XU
  • Publication number: 20100314990
    Abstract: A housing comprises an exterior coating and a substrate. The housing further comprises a first conductive coating, a light emitting coating and a second conductive coating formed between the exterior coating and the substrate. The substrate formed on the second conductive coating by molding. The first and the second conductive coatings include electric contacts. An electronic device using the housing is also described there.
    Type: Application
    Filed: November 13, 2009
    Publication date: December 16, 2010
    Applicants: SHENZHEN FUTAIHONG PRECISION INDUSTRY CO., LTD., FIH (HONG KONG) LIMITED
    Inventors: BEN-DING TSAO, WEN-LIN XIONG, DONG-SHENG WENG, HONG-XI XU, QI-QUAN YAN, DIAN-MING ZHU
  • Patent number: 7592367
    Abstract: Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: September 22, 2009
    Assignee: Hong Kong Jockey Club Institute of Chinese Medicine Ltd.
    Inventors: Quan-Bin Han, Jing-Zheng Song, Chun-Feng Qiao, Ling Yang, Hong-Xi Xu
  • Publication number: 20070149610
    Abstract: Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 28, 2007
    Applicant: Hong Kong Jockey Club Institute of Chinese Medicine Limited
    Inventors: Quan-Bin HAN, Jing-Zheng SONG, Chun-Feng QIAO, Ling YANG, Hong-Xi XU
  • Publication number: 20070148268
    Abstract: Two novel benzofuran glycosides, named psoralenoide and isopsoralenoide, isolated and purified from the seeds of Psoralea corylifolia. The compounds are useful as therapeutic agents for diseases defined under TCM and as a more accurately means of quality control and assessment for Psoralea corylifolia, an important herbs used in TCM.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 28, 2007
    Applicant: Hong Kong Jockey Club Institute of Chinese Medicine Limted
    Inventors: Chun Feng QIAO, Quan-Bin HAN, Jing-Zheng SONG, Shi-Fu MO, Ling-Dong KONG, Hsiang-Fu KUNG, Hong-Xi XU
  • Publication number: 20030215529
    Abstract: In accordance with the present invention, novel compositions useful for the treatment of the cytopathogenic effects of an enveloped virus in mammals have been discovered by extraction and purification from the spikes of Prunella vulgaris. In particular, invention compositions comprise a lignin-carbohydrate complex as an active ingredient for inhibition of viral infection in a mammal. In accordance with an embodiment of the present invention, it has been discovered that invention compositions are effective agents for the prophylaxis and therapy in mammals of diseases caused by enveloped viruses, e.g., herpes simplex virus. Methods for producing invention compositions and uses therefor are also provided.
    Type: Application
    Filed: October 4, 2002
    Publication date: November 20, 2003
    Applicants: Dalhousie University, The Chinese University of Hong Kong
    Inventors: Song F. Lee, Paul P.H. But, Spencer H.S. Lee, Vincent E.C. Ooi, Hong-Xi Xu, Yongwen Zhang, Wai-Chong Foong, Jonathan Blay
  • Patent number: 5916919
    Abstract: A compound composition and method of treating a retrovirus infection are disclosed. In particular, isolated triterpenes have been shown to have significant inhibitory activity against HIV-1.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: June 29, 1999
    Assignees: Dalhousie University, National University of Singapore
    Inventors: Hong-Xi Xu, Keng-Yeow Sim, Fa-Quan Zeng, Min Wan