Patents by Inventor Hongyan Chen
Hongyan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12110485Abstract: Provided is a method for precipitating a starch emulsion, the method including: mixing a fermentation broth with the starch emulsion, the fermentation broth including an isolated microorganism, wherein the isolated microorganism is Leuconostoc citreum WSJ-57 deposited under an accession number of CGMCC No. 19201 in the China General Microbiological Culture Collection Center on Dec. 20, 2019.Type: GrantFiled: November 24, 2020Date of Patent: October 8, 2024Assignees: CHINA AGRICULTURAL UNIVERSITY, SISHUI LIFENG FOOD CO., LTD.Inventors: Xiaojun Liao, Xuan Wang, Liang Zhao, Yongtao Wang, Xiankui Kong, Hongyan Chen, Xueqiang Wang, Guanghua Li
-
Patent number: 11744737Abstract: A skin audible watch for orientation identification includes a dial (1) and a strap (2). A plurality of sound collection modules (3) are arranged along a circumference of the dial (1), and the sound collection modules (3) are sequentially connected with a digital filter (4), an analog-to-digital converter (5), a single-chip microcomputer (6), and a row and column drive module (7); the single-chip microcomputer (6) is also connected with vibration motors (8) and a gyroscope (9); a number of the vibration motors corresponds to a number of orientations; the digital filter (4), analog-to-digital converter, single-chip microcomputer, row and column drive module, the vibration motors and the gyroscope are located inside the dial; the row and column drive module is connected with a current contact pin (12), and a free end of the current contact pin extends out of a surface of the vibration motors.Type: GrantFiled: December 17, 2021Date of Patent: September 5, 2023Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yong Qi, Hongyan Chen, Linshan Yan, Ningzhan Zhang
-
Publication number: 20230250389Abstract: Provided is a microorganism, which is Leuconostoc citreum WSJ-57 deposited under an accession number of CGMCC No. 19201 in the China General Microbiological Culture Collection Center on Dec. 20, 2019.Type: ApplicationFiled: November 24, 2020Publication date: August 10, 2023Inventors: Xiaojun LIAO, Xuan WANG, Liang ZHAO, Yongtao WANG, Xiankui KONG, Hongyan CHEN, Xueqiang WANG, Guanghua LI
-
Publication number: 20220378618Abstract: A skin audible watch for orientation identification includes a dial (1) and a strap (2). A plurality of sound collection modules (3) are arranged along a circumference of the dial (1), and the sound collection modules (3) are sequentially connected with a digital filter (4), an analog-to-digital converter (5), a single-chip microcomputer (6), and a row and column drive module (7); the single-chip microcomputer (6) is also connected with vibration motors (8) and a gyroscope (9); a number of the vibration motors corresponds to a number of orientations; the digital filter (4), analog-to-digital converter, single-chip microcomputer, row and column drive module, the vibration motors and the gyroscope are located inside the dial; the row and column drive module is connected with a current contact pin (12), and a free end of the current contact pin extends out of a surface of the vibration motors.Type: ApplicationFiled: December 17, 2021Publication date: December 1, 2022Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yong QI, Hongyan CHEN, Linshan YAN, Ningzhan ZHANG
-
Patent number: 11286387Abstract: A curable composition comprising a mixture of homopolymers of an aliphatic polyisocyanate and a cycloaliphatic polyisocyanate, a polyester polyol or polyether polyol and a filler. The composition is particularly suitable for use in the manufacture of outdoor insulation system articles.Type: GrantFiled: November 7, 2016Date of Patent: March 29, 2022Inventors: Christian Beisele, Hongyan Chen, Satoru Hishikawa
-
Publication number: 20210395235Abstract: The present application relates to a compound as a TGF-? R1 inhibitor and application thereof. Specifically, provided are a compound of formula I, or an isomer, pharmaceutically acceptable salt, solvent, crystal, or prodrug thereof, preparation methods therefor, and pharmaceutical compositions comprising these compounds, and applications of these compounds or compositions in treating and/or preventing TGF-? R1-related diseases, such as cancer, tissue proliferation diseases, fibrosis, and inflammatory diseases. The compound represents a significant inhibitory activity for TGF-? R1 kinase, and is promising as a treatment agent for TGF-? R1-related diseases.Type: ApplicationFiled: October 17, 2019Publication date: December 23, 2021Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Yan ZHANG, Xiaowei WANG, Hai WANG, Zhuang GUO, Kunzhi LV, Yujie CHANG, Hongyan CHEN, Guofeng XU
-
Patent number: 11186587Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.Type: GrantFiled: July 25, 2018Date of Patent: November 30, 2021Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Yazhou Wang, Xu Quan, Chunhuan Jiang, Hongyan Chen, Menghua Chen, Chao Li, Yexin Liao, Qi Liu, Chen Wang, Hai Wang, Shengwei Yang, Guochuang Zheng
-
Patent number: 10739921Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.Type: GrantFiled: July 27, 2018Date of Patent: August 11, 2020Assignee: NANCHANG O-FILM DISPLAY TECHNOLOGY CO., LTDInventors: Hongyan Chen, Rongzhi Gu, Weiting Huang, Xiaowei Hou
-
Patent number: 10696820Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.Type: GrantFiled: March 10, 2016Date of Patent: June 30, 2020Assignee: HUNTSMAN INTERNATIONAL LLCInventors: Christian Beisele, Zhijian Liu, Hongyan Chen, Satoru Hishikawa
-
Publication number: 20200165265Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.Type: ApplicationFiled: July 25, 2018Publication date: May 28, 2020Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Xu QUAN, Chunhuan JIANG, Hongyan CHEN, Menghua CHEN, Chao LI, Yexin LIAO, Qi LIU, Chen WANG, Hai WANG, Shengwei YANG, Guochuang ZHENG
-
Publication number: 20190095003Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.Type: ApplicationFiled: July 27, 2018Publication date: March 28, 2019Applicant: NANCHAGN O-FILM DISPLAY TECHNOLOGY CO.,LTDInventors: Hongyan CHEN, Rongzhi GU, Weiting HUANG, Xiaowei HOU
-
Publication number: 20180346717Abstract: A curable composition comprising (A) a mixture of homopolymers of polyisocyanates comprising (a1) from 50 wt % to 90 wt % of at least one homopolymer of an aliphatic poly-isocyanate, and (a2) from 10 wt % to 50 wt % of at least one homopolymer of a cycloaliphatic poly-isocyanate, each based on the total weight of (a1) and (a2), (B) at least one polyol selected from the group of polyether polyol and polyester polyol, (C) at least one filler selected from the group of quartz sand, quartz powder, silica, aluminium oxide, titanium oxide, zirconium oxide, Mg(OH)2, AI(OH)3, dolomite [CaMg (CO3)2], AIO(OH), silicon nitride, boron nitride, aluminium nitride, silicon carbide, boron carbide, chalk, calcium carbonate, barite, gypsum, hydromagnesite, zeolites, talcum, mica, kaolin and wollastonite, wherein the at least one filler may be silanized, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnationType: ApplicationFiled: November 7, 2016Publication date: December 6, 2018Applicant: Huntsman Advanced Materials Licensing (Switzerland) GmbHInventors: Christian BEISELE, Hongyan CHEN, Satoru HISHIKAWA
-
Patent number: 9963480Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:Type: GrantFiled: March 6, 2014Date of Patent: May 8, 2018Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Xian Zhang, Sheng Bi, Yiping Gao, Hongyan Chen, Dezhong Wang, Yang Nan, Cang Zhang, Yuxiu Li, Di Zhang
-
Publication number: 20180118922Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.Type: ApplicationFiled: March 10, 2016Publication date: May 3, 2018Inventors: Christian BEISELE, Zhijian LIU, Hongyan CHEN, Satoru HISHIKAWA
-
Patent number: 9512108Abstract: The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.Type: GrantFiled: December 26, 2014Date of Patent: December 6, 2016Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Dezhong Wang, Haiping Zhou, Xian Zhang, Hongyan Chen, Di Zhang, Cang Zhang
-
Publication number: 20160297804Abstract: The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.Type: ApplicationFiled: December 26, 2014Publication date: October 13, 2016Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Dezhong WANG, Haiping ZHOU, Xian ZHANG, Hongyan CHEN, Di ZHANG, Cang ZHANG
-
Patent number: 9255107Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.Type: GrantFiled: November 27, 2013Date of Patent: February 9, 2016Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Di Zhang, Feng Wu, Sheng Bi, Yiping Gao, Hongbin Chen, Hongyan Chen, Cang Zhang, Yang Nan, Yang Liu
-
Publication number: 20150361123Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.Type: ApplicationFiled: March 6, 2014Publication date: December 17, 2015Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTDInventors: Yong WANG, Liwen ZHAO, Xian ZHANG, Sheng BI, Yiping GAO, Hongyan CHEN, Dezhong WANG, Yang NAN, Cang ZHANG, Yuxiu LI, Di ZHANG
-
Publication number: 20150299202Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.Type: ApplicationFiled: November 27, 2013Publication date: October 22, 2015Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Di ZHANG, Feng WU, Sheng BI, Yiping GAO, Hongbin CHEN, Hongyan CHEN, Cang ZHANG, Yang NAN, Yang LIU
-
Publication number: 20150152088Abstract: The present invention belongs to the field of pharmaceutical chemistry, and specifically relates to compounds having an alkynyl heteroaromatic ring structure and pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates, or prodrugs thereof, and pharmaceutical compositions comprising these compounds, as well as uses of these compounds and compositions in the manufacture of a medicament. The compounds of the present invention and the pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates or prodrugs thereof and the pharmaceutical compositions comprising the compounds have better anti-tumor activity.Type: ApplicationFiled: September 12, 2013Publication date: June 4, 2015Applicant: Nanjing Sanhome Pharmaceutical Co., Ltd.Inventors: Yong Wang, Liwen Zhao, Wenping Zhang, Hongyan Chen, Sheng Bi, Yiping Gao, Hongbin Chen, Yang Liu, Xin Xu, Cang Zhang