Abstract: Described herein is N-[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(R)-[(1-oxo-2-propen-1-yl)amino]-1-piperidinyl]methyl]-2-pyridinecarboxamide, including crystalline forms, solvates, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the compound, as well as methods of using the compound, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.

Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof. Methods associated with the preparation and use of the disclosed compounds, as well as pharmaceutical compositions comprising such compounds are also disclosed.

Abstract: A vertical circulation charging pile structure for stereo garage includes a parking garage workstation, a foundation, a pillar frame member fixed to the foundation, a deceleration motor and transmission member, a sprocket and link member, a car carrying frame member, a charging pile, a flexible charging wire, a charging interface socket, a charging interface plug provided at a top center of the foundation, and an electric push rod provided below the charging interface plug and communicated with the parking garage workstation. The pillar frame member is provided with the deceleration motor and transmission member. During power-on, the deceleration motor and transmission member drives rotation of the sprocket and link member synchronously rotation of a plurality of car carrying frame members. Each car carrying frame members is provided with one charging pile and one charging interface socket. Adjacent two charging piles are communicated by flexible charging wires.

Abstract: A biodegradable cross-linked polymer and methods of preparing same are provided. The biodegradable cross-linked polymer is formed from a biodegradable polymeric material having two or more arms, which is a random copolymer formed of a first monomer and a second monomer different from the first monomer. The first monomer is selected from the group consisting of L-lactide, DL-lactide, glycolid, ?-caprolactone, trimethylene carbonate, p-dioxanone, amino acid-derived polycarbonates and polyorthoesters. The second monomer is one or two selected from the group consisting of D-lactide, DL-lactide, glycolide, ?-caprolactone, trimethyl carbonate, salicylic acid, carbonates, amino acids and derivatives thereof. The biodegradable polymeric material has a molecular weight of from 5,000 to 1,200,000 and an intrinsic viscosity of from 0.1 to 9.0 dl/g. Each of the terminal groups on the arms of the biodegradable polymeric material is selected from the group consisting of hydroxyl amino and carboxyl groups.

Abstract: A biodegradable cross-linked polymer and methods of preparing same are provided. The biodegradable cross-linked polymer is formed from a biodegradable polymeric material having two or more arms, which is a random copolymer formed of a first monomer and a second monomer different from the first monomer. The first monomer is selected from the group consisting of L-lactide, DL-lactide, glycolid, ?-caprolactone, trimethylene carbonate, p-dioxanone, amino acid-derived polycarbonates and polyorthoesters. The second monomer is one or two selected from the group consisting of D-lactide, DL-lactide, glycolide, ?-caprolactone, trimethyl carbonate, salicylic acid, carbonates, amino acids and derivatives thereof. The biodegradable polymeric material has a molecular weight of from 5,000 to 1,200,000 and an intrinsic viscosity of from 0.1 to 9.0 dl/g. Each of the terminal groups on the arms of the biodegradable polymeric material is selected from the group consisting of hydroxyl amino and carboxyl groups.

Abstract: The present invention relates to the field of medical instruments. Specifically, a biodegradable cross-linked polymer and a manufacturing method therefor are provided. The cross-linked polymer is obtained by bonding crosslinkable reactive groups to terminal groups of a biodegradable prepolymer having two or more arms and further subjecting the prepolymer to thermal polymerization and/or light irradiation. The cross-linked polymer has an elastic modulus of 10-4,500 MPa, and a degradation rate of 3-36 months. A biodegradable vascular stent and a preparation method therefor are also provided. The vascular stent is formed by laser cutting of polymeric tubing having a three-dimensional cross-linked network structure. The vascular stent has ample mechanical strength, a high elastic modulus at body temperature, and a regulatable degradation rate.

Abstract: The present invention relates to the field of medical instruments. Specifically, a biodegradable cross-linked polymer and a manufacturing method therefor are provided. The cross-linked polymer is obtained by bonding crosslinkable reactive groups to terminal groups of a biodegradable prepolymer having two or more arms and further subjecting the prepolymer to thermal polymerization and/or light irradiation. The cross-linked polymer has an elastic modulus of 10-4,500 MPa, and a degradation rate of 3-36 months. A biodegradable vascular stent and a preparation method therefor are also provided. The vascular stent is formed by laser cutting of polymeric tubing having a three-dimensional cross-linked network structure. The vascular stent has ample mechanical strength, a high elastic modulus at body temperature, and a regulatable degradation rate.

Abstract: A system including a content server and a plurality of instant messaging clients is configured to enable each client device to scan for malware on incoming or outgoing instant messages. The content server may receive malware configuration information and distribute the malware configuration information to each client device. Each client device may employ the malware configuration information to perform a number of actions, including determining one or more malware scanners to use, selectively scanning incoming or outgoing instant messages, reporting instances of malware that are detected, or selectively restricting one or more instant messaging functions. The system may include a malware information repository that receives and reports of detected malware, analyzes the reports, and determines sources of malware.

Abstract: A method and system of controlling contamination within an HDD with a surface modified MCM 41/48 material. The method includes encasing the hard disk drive and a mesoporous material in an enclosure of the hard disk drive, wherein the mesoporous material sorbs contaminants within said enclosure.

Abstract: Connecting a preamplifier to a printed circuit board assembly on a hard disk drive. The disk includes a housing, a head stack assembly coupled with the housing, a printed circuit board assembly comprising via holes, a preamplifier coupled with the head stack assembly, and at least one deformable pogo pin configured to mechanically and communicatively connect the printed circuit board assembly to the preamplifier upon insertion into the via holes, further configured to comprise a tip and a shaft, and further configured to deform upon insertion into the via holes.

Abstract: A method and system of controlling contamination within an HDD with a surface modified MCM 41/48 material. The method includes encasing the hard disk drive and a mesoporous material in an enclosure of the hard disk drive, wherein the mesoporous material sorbs contaminants within said enclosure.

Abstract: Connecting a preamplifier to a printed circuit board assembly on a hard disk drive. The disk includes a housing, a head stack assembly coupled with the housing, a printed circuit board assembly comprising via holes, a preamplifier coupled with the head stack assembly, and at least one deformable pogo pin configured to mechanically and communicatively connect the printed circuit board assembly to the preamplifier upon insertion into the via holes, further configured to comprise a tip and a shaft, and further configured to deform upon insertion into the via holes.

Abstract: The present invention concerns blends comprising at least one shape memory polymer and at least one thermoplastic polymer, wherein this thermoplastic polymer does not show shape memory properties. The present invention furthermore concerns methods for preparing such blends and the use of these blends in various applications, including additional products, household equipment etc.

Abstract: In accordance with certain aspects of the present invention, there is provided system and method for reducing the production cycle in the manufacturing of hard disk drives and a generic hard disk drive ready for customization. In one embodiment of the present invention a generic hard disk drive is provided. The generic disk drive includes a hard disk drive assembly and a printed circuit board having an electronic system for controlling the hard disk drive assembly with associated custom microcode specified by a customer during the customization of the generic disk drive.

Abstract: A system including a content server and a plurality of instant messaging clients is configured to enable each client device to scan for malware on incoming or outgoing instant messages. The content server may receive malware configuration information and distribute the malware configuration information to each client device. Each client device may employ the malware configuration information to perform a number of actions, including determining one or more malware scanners to use, selectively scanning incoming or outgoing instant messages, reporting instances of malware that are detected, or selectively restricting one or more instant messaging functions. The system may include a malware information repository that receives and reports of detected malware, analyzes the reports, and determines sources of malware.