Patents by Inventor Hong Zhu

Hong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING A STREPTOMYCES-BASED BIOLOGICAL CONTROL AGENT AND A FUNGICIDE
    Publication number: 20140228214
    Abstract: The present invention relates to a composition comprising at least one biological control agent selected from the group consisting of Streptomyces strains, preferably gougerotin-producing Streptomyces strains such as Streptomyces microflavus strain NRRL B-50550 and/or a mutant thereof having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens and at least one fungicide (I) in a synergistically effective amount, with the proviso that the biological control agent and fungicide (I) are not identical. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 14, 2014
    Applicant: BAYER CROPSCIENCE LP
    Inventors: Wolfram ANDERSCH, Damian CURTIS, Shaohua GUAN, Magalie GUILHABERT-GOYA, Reed Nathan ROYALTY, Frisby Davis SMITH, Bernd SPRINGER, Wolfgang THIELERT, Ulrike WACHENDORFF-NEUMANN, Hong ZHU
  • COMPOSITIONS COMPRISING A STREPTOMYCES-BASED BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE
    Publication number: 20140228213
    Abstract: The present invention relates to a composition comprising at least one biological control agent selected from the group consisting of Streptomyces microflavus strain NRRL B-50550 and/or a mutant thereof having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens and at least one insecticide in a synergistically effective amount, with the proviso that the biological control agent and the insecticide are not identical. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 14, 2014
    Applicant: BAYER CROPSCIENE LP
    Inventors: Wolfram ANDERSCH, Damian CURTIS, Shaohua GUAN, Magalie GUILHABERT-GOYA, Reed Nathan ROYALTY, Bernd Springer, Wolfgang THIELERT, Hong ZHU
  • INFUSION PUMP AND METHOD TO ENHANCE LONG TERM MEDICATION DELIVERY ACCURACY
    Publication number: 20140207057
    Abstract: An infusion pump is provided for pumping fluid though an administration set at a constant flow rate. The pump includes a pumping mechanism for pumping fluid and operates at a pulse frequency, and a controller controls the pulse frequency. Additionally, the pump has one or more sensors configured for measuring at least one characteristic value relating to a status of the infusion pump. The controller is configured for causing the pumping mechanism to operate at a first pulse frequency, and the one or more sensors measure the characteristic value intermittently. When the measured characteristic value meets a threshold value, the controller causes the pumping mechanism to operate at a second pulse frequency different from the first pulse frequency.
    Type: Application
    Filed: January 21, 2013
    Publication date: July 24, 2014
    Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.
    Inventor: Hong Zhu
  • NOVEL STRAINS OF STREPTOMYCES MICROFLAVUS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS
    Publication number: 20140107061
    Abstract: The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions, wherein the culture medium contains an amino acid at a concentration effective to achieve a gougerotin concentration of at least 1 g/L.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 17, 2014
    Applicant: Bayer CropScience LP
    Inventors: Damian CURTIS, Shaohua GUAN, Magalie GUILHABERT-GOYA, Jonathan S. MARGOLIS, Reed Nathan ROYALTY, Gerardo Bueno SALAZAR, David SESIN, Frisby Davis SMITH, Colleen TAYLOR, Hong ZHU
  • STREPTOMYCES MICROFLAVUS STRAINS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS
    Publication number: 20140105862
    Abstract: The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions, wherein the culture medium contains an amino acid at a concentration effective to achieve a gougerotin concentration of at least 1 g/L.
    Type: Application
    Filed: October 11, 2013
    Publication date: April 17, 2014
    Applicant: Bayer CropScience LP
    Inventors: Brian CAMPBELL, Damian CURTIS, Shaohua GUAN, Magalie GUILHABERT-GOYA, Daniel M. JOO, Tara LU, Jonathan S. MARGOLIS, Reed Nathan ROYALTY, Gerardo Bueno SALAZAR, David SESIN, Frisby Davis SMITH, Colleen TAYLOR, Hong ZHU
  • Cells useful for immuno-based botulinum toxin serotype a activity assays
    Patent number: 8691566
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: April 8, 2014
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays
    Publication number: 20140093957
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Application
    Filed: December 28, 2011
    Publication date: April 3, 2014
    Inventors: Hong Zhu, Joanne Wang, Birgitte P.S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • METHOD OF INCREASING ABIOTIC STRESS RESISTANCE OF A PLANT
    Publication number: 20140066302
    Abstract: The invention relates to a method of increasing abiotic stress resistance enhancing soil nutrition of a plant, the method comprising applying a composition comprising Bacillus subtilis or Bacillus pumilus or a mutant thereof, to the plant, to a part of the plant and/or to an area around the plant or plant part. The invention also is directed to a method of enhancing soil nutrition comprising applying a composition comprising Bacillus subtilis or a mutant thereof to the soil.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 6, 2014
    Applicant: Bayer CropScience LP
    Inventors: Magalie GUILHABERT-GOYA, Hong ZHU
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8663982
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: March 4, 2014
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8663983
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: March 4, 2014
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • INSECTICIDAL FERMENTATION BROTH FROM ACTINOMYCETES CONTAINING ENHANCED RATIO OF ACTIVE TO INACTIVE DUNAIMYCINS
    Publication number: 20130345442
    Abstract: Methods and compositions are provided for the preparation of insecticidal compositions.
    Type: Application
    Filed: August 21, 2013
    Publication date: December 26, 2013
    Applicant: Bayer CropScience LP
    Inventors: Hong ZHU, Jorge JIMENEZ, Colleen TAYLOR, Magalie GUILHABERT-GOYA, Jonathan MARGOLIS
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8603812
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: December 10, 2013
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8603813
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: December 10, 2013
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Immuno-Based Retargeted Endopeptidase Activity Assays
    Publication number: 20130267010
    Abstract: The present specification discloses a retargeted endopeptidase pharmaceutical wherein the activity has been determined by the methods disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 10, 2013
    Inventors: Joanne Wang, Hong Zhu, Dianne D. Hodges, Ester Femandez-Salas
  • Insecticidal fermentation broth from actinomycetes containing enhanced ratio of active to inactive dunaimycins
    Patent number: 8541216
    Abstract: The present invention provides an insecticidal fermentation broth of an actinomycete, where the fermentation broth contains an optimized ratio of active dunaimycins to inactive dunaimycins.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: September 24, 2013
    Assignee: Bayer CropScience LP
    Inventors: Hong Zhu, Jorge Jimenez, Colleen Taylor, Magalie Guilhabert-Goya, Jonathan Margolis
  • Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays
    Publication number: 20130236963
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Application
    Filed: December 28, 2011
    Publication date: September 12, 2013
    Inventors: Hong Zhu, Joanne Wang, Birgitte P.S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • CMOS image sensor with non-contact structure
    Patent number: 8513721
    Abstract: A complementary metal oxide semiconductor (CMOS) image sensor device includes a capacitive coupled photodiode that is formed within a region of a semiconductor substrate. The photodiode receives an incident light and generates a corresponding electric charge. The CMOS image sensor device includes a reset transistor coupled to the photodiode for reverse biasing the photodiode with a predetermined voltage. The CMOS image sensor device further includes a buffer circuit and a capacitor, which is interposed between the photodiode and the buffer circuit. The capacitor is configured to transfer the electric charge to the buffer circuit. The buffer circuit may include an emitter follower or a source follower transistor.
    Type: Grant
    Filed: October 11, 2010
    Date of Patent: August 20, 2013
    Assignees: Semiconductor Manufacturing International (Shanghai) Corporation, Semiconductor Manufacturing International (Bejing) Corporation
    Inventors: Hong Zhu, Liwei Wu, Jessy Xu, Samuel Leng, Celia Xin, Jim Yang
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8507271
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: August 13, 2013
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Cells useful for immuno-based botulinum toxin serotype A activity assays
    Patent number: 8501469
    Abstract: The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: August 6, 2013
    Assignee: Allergan, Inc.
    Inventors: Hong Zhu, Joanne Wang, Birgitte P. S. Jacky, D. Dianne Hodges, Fernandez-Salas Ester
  • Electronic device
    Patent number: D712406
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: September 2, 2014
    Assignee: Synergy Optoelectronics (Shenzhen) Co., Ltd.
    Inventors: Chien-Yu Tseng, Xing-Xing Yang, Zhi-Hong Zhu