Patents by Inventor Hong Zhuang
Hong Zhuang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11485705Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: GrantFiled: May 22, 2020Date of Patent: November 1, 2022Assignee: LUMOS PHARMA, INC.Inventors: Mario Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Hima Potturi, Hong Zhuang
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Patent number: 10780481Abstract: A bending and molding mechanism includes two bases, wherein the bases are provided with a transverse sliding rail, two transverse sliding bases are disposed on the transverse sliding rail in a sliding manner, the base is provided with a transverse driving device driving the transverse sliding bases, the base is provided with a central clamping device, the transverse sliding bases are provided with a longitudinal sliding rail, the longitudinal sliding rail is provided with a longitudinal sliding base, the transverse sliding bases are provided with a longitudinal driving device driving the longitudinal sliding base to slide, the longitudinal sliding base is provided with a bending and molding device, one side of the transverse sliding base at the left side is provided with a left clamping device, and one side of the transverse sliding base at the right side is provided with a right clamping device.Type: GrantFiled: February 22, 2016Date of Patent: September 22, 2020Assignees: JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE OF ZHANGJIAGANG, JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Wenxian Tang, Jian Zhang, Hongcai Lin, Yang Zhang, Shijie Su, Shifeng Hang, Hong Zhuang
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Publication number: 20200283385Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: ApplicationFiled: May 22, 2020Publication date: September 10, 2020Inventors: Mario MAUTINO, Sanjeev KUMAR, Firoz JAIPURI, Jesse WALDO, Hima POTTURI, Hong ZHUANG
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Patent number: 10623619Abstract: An image-capture-scope indication device for an image-capture apparatus. The image-capture-scope indication device includes: a light source, fixed on a surface of the image-capture apparatus on which a lens of the image-capture apparatus is provided; a light ray selection member, which is provided in front of the light source and has a light transmission portion; and a drive member. The drive member is configured for moving the light ray selection member so that a scope surrounded by light rays emitted from the light source and passing through the light transmission portion of the light ray selection member is provided that is consistent with an image-capture-scope of the image-capture apparatus.Type: GrantFiled: April 3, 2019Date of Patent: April 14, 2020Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Hao Chang, Yan Zheng Sun, Lijun Wei, Qing Hong Zhuang
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Patent number: 10596601Abstract: The image sorting system sorts normal chicken breast meat fillets from chicken fillets that exhibit wooden breast myopathy (i.e. WB fillets). In the preferred embodiment, a camera and associated controller gather data and construct a digital image of a chicken breast fillet as it travels on a conveyer belt. The digital image is used to calculate a centroid (i.e. center of mass) of the fillet. As the fillet moves over a nose of the conveyor belt and free-falls to a lower conveyor belt, the controller determines the distance between the fillet centroid and a reference point (preferably the conveyer belt axis of rotation). If the distance exceeds a predetermined minimum distance, the fillet is designated a WB fillet.Type: GrantFiled: May 15, 2018Date of Patent: March 24, 2020Assignee: The United States of America, as represented by the Secretary of AgricultureInventors: Seung C. Yoon, Brian C. Bowker, Hong Zhuang, Kurt C. Lawrence, Gerald W. Heitschmidt, Tae Sung Shin
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Patent number: 10450098Abstract: Disclosed is a synergistic sterilizing and preserving method for fresh meat with high voltage electric field plasma and nano photocatalysis, which belongs to the technical field of cold sterilization of food package. The method comprises the steps: uniformly mixing a photocatalyst, a coupling agent and coating liquid at a high speed, performing the coupling to obtain modified coating liquid, smearing the coating liquid onto the surface of a plastic packaging film to obtain a packaging material with a photocatalytic bacteriostatic function, packaging fresh meat in an MAP (modified atmosphere packing) manner by adopting the bacteriostatic packaging material, wherein a coating containing the photocatalytic material is disposed at the inner side of a package, placing the packed fresh meat between two electrodes of a plasma generating device, and performing the plasma sterilization under the condition of a high voltage electric field.Type: GrantFiled: October 21, 2014Date of Patent: October 22, 2019Assignee: NANJING AGRICULTURAL UNIVERSITYInventors: Jianhao Zhang, Jiamei Wang, Hong Zhuang
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Publication number: 20190248739Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: ApplicationFiled: February 15, 2019Publication date: August 15, 2019Inventors: Mario MAUTINO, Sanjeev KUMAR, Firoz JAIPURI, Jesse WALDO, Hima POTTURI, Hong ZHUANG
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Patent number: 10375281Abstract: An image-capture-scope indication device for an image-capture apparatus. The image-capture-scope indication device includes: a light source, fixed on a surface of the image-capture apparatus on which a lens of the image-capture apparatus is provided; a light ray selection member, which is provided in front of the light source and has a light transmission portion; and a drive member. The drive member is configured for moving the light ray selection member so that a scope surrounded by light rays emitted from the light source and passing through the light transmission portion of the light ray selection member is provided that is consistent with an image-capture-scope of the image-capture apparatus.Type: GrantFiled: October 20, 2015Date of Patent: August 6, 2019Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Hao Chang, Yan Zheng Sun, Lijun Wei, Qing Hong Zhuang
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Publication number: 20190230263Abstract: An image-capture-scope indication device for an image-capture apparatus. The image-capture-scope indication device includes: a light source, fixed on a surface of the image-capture apparatus on which a lens of the image-capture apparatus is provided; a light ray selection member, which is provided in front of the light source and has a light transmission portion; and a drive member. The drive member is configured for moving the light ray selection member so that a scope surrounded by light rays emitted from the light source and passing through the light transmission portion of the light ray selection member is provided that is consistent with an image-capture-scope of the image-capture apparatus.Type: ApplicationFiled: April 3, 2019Publication date: July 25, 2019Inventors: Hao CHANG, Yan Zheng SUN, Lijun WEI, Qing Hong ZHUANG
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Patent number: 10207990Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: GrantFiled: June 27, 2017Date of Patent: February 19, 2019Assignee: NEWLINK GENETICS CORPORATIONInventors: Mario Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Hima Potturi, Hong Zhuang
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Publication number: 20180333752Abstract: The image sorting system sorts normal chicken breast meat fillets from chicken fillets that exhibit wooden breast myopathy (i.e. WB fillets). In the preferred embodiment, a camera and associated controller gather data and construct a digital image of a chicken breast fillet as it travels on a conveyer belt. The digital image is used to calculate a centroid (i.e. center of mass) of the fillet. As the fillet moves over a nose of the conveyor belt and free-falls to a lower conveyor belt, the controller determines the distance between the fillet centroid and a reference point (preferably the conveyer belt axis of rotation). If the distance exceeds a predetermined minimum distance, the fillet is designated a WB fillet.Type: ApplicationFiled: May 15, 2018Publication date: November 22, 2018Inventors: SEUNG C. YOON, BRIAN C. BOWKER, HONG ZHUANG, KURT C. LAWRENCE, GERALD W. HEITSCHMIDT, TAE SUNG SHIN
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Publication number: 20180134658Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: ApplicationFiled: June 27, 2017Publication date: May 17, 2018Inventors: Mario Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Hima Potturi, Hong Zhuang
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Publication number: 20180036781Abstract: The present invention discloses a bending and molding mechanism, comprising a base, wherein the base is provide with a transverse sliding rail, two transverse sliding bases are disposed on the transverse sliding rail in a sliding manner, the base is provided with a transverse driving device driving the transverse sliding bases, the base is provided with a central clamping device which can clamp the wire and can rotate around a central axis of the wire between the two transverse sliding bases, the transverse sliding bases are provided with a longitudinal sliding rail, the longitudinal sliding rail is provided with a longitudinal sliding base, the transverse sliding bases are provided with a longitudinal driving device driving the longitudinal sliding base to slide, the longitudinal sliding base is provided with a bending and molding device, one side, close to the central clamping device, of the transverse sliding base at the left side is provided with a left clamping device capable of movably extending to clamType: ApplicationFiled: February 22, 2016Publication date: February 8, 2018Inventors: Wenxian TANG, Jian ZHANG, Hongcai LIN, Yang ZHANG, Shijie SU, Shifeng HANG, Hong ZHUANG
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Patent number: 9732035Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: GrantFiled: June 2, 2016Date of Patent: August 15, 2017Assignee: NEWLINK GENETICS CORPORATIONInventors: Mario Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Hima Potturi, Hong Zhuang
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Patent number: 9626497Abstract: A system for sharing a USB Key by multiple virtual machines located at different hosts including at least two virtual machine managers, each virtual machine manager including a virtual machine transceiver module which is configured to receive a request for accessing a USB Key from a virtual machine within its host; a storage module which is configured to store an association relationship between a USB Key and the virtual machine authenticated by the USB Key; a verification module which is configured to, in response to judging that the virtual machine of the received request can access the USB Key, transmit the request for accessing the USB Key to a USB Key transceiver module of a virtual machine manager of the host where the USB Key is located; and a USB Key transceiver module which is configured to receive a request for accessing a USB Key, and to transmit an access request to a connected USB Key.Type: GrantFiled: April 5, 2016Date of Patent: April 18, 2017Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Lijun Wei, Binqi Zhang, Qian Zhang, Qing Hong Zhuang
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Publication number: 20170043895Abstract: Disclosed is a synergistic sterilizing and preserving method for fresh meat with high voltage electric field plasma and nano photocatalysis, which belongs to the technical field of cold sterilization of food package. The method comprises the steps: uniformly mixing a photocatalyst, a coupling agent and coating liquid at a high speed, performing the coupling to obtain modified coating liquid, smearing the coating liquid onto fee surface of a plastic packaging film to obtain a packaging material with a photocatalytic bacteriostatic function, packaging fresh meat in an MAP (modified atmosphere packing) manner by adopting the bacteriostatic packaging material, wherein a coating containing fee photocatalytic material is disposed at the inner side of a package, placing the packed fresh meat between two electrodes of a plasma generating device, and performing the plasma sterilization under the condition of a high voltage electric field.Type: ApplicationFiled: October 21, 2014Publication date: February 16, 2017Applicant: NANJING AGRICULTURAL UNIVERSITYInventors: Jianhao ZHANG, Jiamei WANG, Hong ZHUANG
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Publication number: 20170022157Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.Type: ApplicationFiled: June 2, 2016Publication date: January 26, 2017Inventors: Mario MAUTINO, Sanjeev KUMAR, Firoz JAIPURI, Jesse WALDO, Hima POTTURI, Hong ZHUANG
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Publication number: 20160219041Abstract: A system for sharing a USB Key by multiple virtual machines located at different hosts including at least two virtual machine managers, each virtual machine manager including a virtual machine transceiver module which is configured to receive a request for accessing a USB Key from a virtual machine within its host; a storage module which is configured to store an association relationship between a USB Key and the virtual machine authenticated by the USB Key; a verification module which is configured to, in response to judging that the virtual machine of the received request can access the USB Key, transmit the request for accessing the USB Key to a USB Key transceiver module of a virtual machine manager of the host where the USB Key is located; and a USB Key transceiver module which is configured to receive a request for accessing a USB Key, and to transmit an access request to a connected USB Key.Type: ApplicationFiled: April 5, 2016Publication date: July 28, 2016Inventors: Lijun Wei, Binqi Zhang, Qian Zhang, Qing Hong Zhuang
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Publication number: 20160127622Abstract: An image-capture-scope indication device for an image-capture apparatus. The image-capture-scope indication device includes: a light source, fixed on a surface of the image-capture apparatus on which a lens of the image-capture apparatus is provided; a light ray selection member, which is provided in front of the light source and has a light transmission portion; and a drive member. The drive member is configured for moving the light ray selection member so that a scope surrounded by light rays emitted from the light source and passing through the light transmission portion of the light ray selection member is provided that is consistent with an image-capture-scope of the image-capture apparatus.Type: ApplicationFiled: October 20, 2015Publication date: May 5, 2016Inventors: Hao CHANG, Yan Zheng SUN, Lijun WEI, Qing Hong ZHUANG
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Patent number: 9311471Abstract: A system for sharing a USB Key by multiple virtual machines located at different hosts including at least two virtual machine managers, each virtual machine manager including a virtual machine transceiver module which is configured to receive a request for accessing a USB Key from a virtual machine within its host; a storage module which is configured to store an association relationship between a USB Key and the virtual machine authenticated by the USB Key; a verification module which is configured to, in response to judging that the virtual machine of the received request can access the USB Key, transmit the request for accessing the USB Key to a USB Key transceiver module of a virtual machine manager of the host where the USB Key is located; and a USB Key transceiver module which is configured to receive a request for accessing a USB Key, and to transmit an access request to a connected USB Key.Type: GrantFiled: June 17, 2014Date of Patent: April 12, 2016Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Lijun Wei, Binqi Zhang, Qian Zhang, Qing Hong Zhuang