Abstract: The present disclosure relates to a flexible pad and a display device. The flexible pad includes a bottom surface; a contact curved surface opposite to the bottom surface, wherein the contact curved surface is configured to be bonded with a display panel; a first side surface; a second side surface opposite to the first side surface; a third side surface; and a fourth side surface opposite to the third side surface; wherein a preset connecting line direction between the first side surface and the second side surface is a first direction, and in the first direction, a distance between the third side surface and the fourth side surface gradually increases from a middle to two sides.

Abstract: Disclosed in the present disclosure are a flood event identification method and apparatus, an electronic device, and a readable storage medium. The method includes: obtaining runoff time sequence data; obtaining initial peak occurrence time by using N continuous first-order difference values in a first-order difference sequence of the runoff time sequence data; obtaining initial start and end time by using M continuous first-order difference values in the first-order difference sequence; and screening out determined peak occurrence time from the initial peak occurrence time, and screening out start and end time corresponding to the peak occurrence time from the initial start and end time. With the technical solution provided by the present disclosure, flood events can be automatically selected with high efficiency and accuracy.

Abstract: A method for quickly optimizing key mining parameters of an outburst coal seam as provided includes steps of constructing a graphic basic information model of the coal mine, giving coal mine characteristic information, performing mining simulation, constructing a CNN-LSTM predicating model, obtaining changes under different mining conditions, constructing a Lorenz chaotic primer, and the like. The model can be improved with continuous breakthroughs in theory, so that the model has a strong learning ability and can adapt to the constantly changing complex geological environment. The method has very good predictability for the determination of coal seam group parameters, and can efficiently select and output a set of candidate parameters.

Abstract: An in-situ detection robot and method for geological information without disturbance of in-situ stress, including a sleeve, a drilling unit set at the top of the sleeve, a dumping unit set inside the sleeve, and a support propulsion unit is set outside the sleeve, the top of the dumping unit extends into the drilling unit, a detection unit is set between the drilling unit and the support propulsion unit, and the robot tail is connected to a control unit; the dumping unit is used to discharge soil drilled from a hole of the drilling unit to the ground, the support propulsion unit is used to realize support, the detection unit is used to detect geological information of surrounding environment of the robot, the control unit is used to control the drilling unit, the support propulsion unit and the detection unit, and the control unit collects and processes the geological information.

Abstract: The present invention discloses an optimization method for natural gas pipeline operation under the carbon neutrality target. From the perspective of energy structure adjustment, the present invention proposes a complete low-carbon and low-consumption optimization model of long-distance natural gas transmission network, which is used for fine calculation of multi-energy carbon emissions and energy consumption in the transportation process of natural gas pipeline network; according to different energy structure backgrounds, the corresponding objective function for minimum carbon emissions is established, the optimization algorithm is adopted to solve the objective function for minimum carbon emissions and work out the optimal scheduling scheme.

Abstract: The present disclosure relates to the technical field of vehicle steering, and provides an electrically adjustable steering column and an electric power steering system.

Abstract: Described herein are immune cells comprising: a T-cell receptor (TCR) and a chimeric stimulating receptor (CSR) that comprises (i) a ligand-binding module that is capable of binding or interacting with a target ligand; (ii) a transmembrane domain; and (iii) a CD30 costimulatory domain, in which the CSR in the immune cells lacks a functional primary signaling domain. Also provided herein are methods of using the same or components thereof (e.g., the CSR) for therapeutic treatment of cancers (e.g., solid tumor cancers).

Abstract: The present disclosure relates to the technical field of vehicle steering, and provides an electrically adjustable steering column and an electric power steering system.

Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.

Abstract: The present invention discloses an optimization method for natural gas pipeline operation under the carbon neutrality target. From the perspective of energy structure adjustment, the present invention proposes a complete low-carbon and low-consumption optimization model of long-distance natural gas transmission network, which is used for fine calculation of multi-energy carbon emissions and energy consumption in the transportation process of natural gas pipeline network; according to different energy structure backgrounds, the corresponding objective function for minimum carbon emissions is established, the optimization algorithm is adopted to solve the objective function for minimum carbon emissions and work out the optimal scheduling scheme.

Abstract: Provided herein are components (e.g., cells and soluble proteins), systems, and methods for assessing the biological activity of soluble proteins comprising an Fc domain and a CD28-binding domain (e.g., CD80 extracellular domain Fc fusion proteins).

Abstract: Described herein are immune cells comprising: a chimeric antigen receptor (CAR) that comprises (i) an extracellular target-binding domain comprising an antibody moiety; (ii) a transmembrane domain; and (iii) a primary signaling domain, and a chimeric stimulating receptor (CSR) that comprises (i) a ligand-binding module that is capable of binding or interacting with a target ligand; (ii) a transmembrane domain; and (iii) a CD30 costimulatory domain, in which the CSR in the immune cells lacks a functional primary signaling domain. Also provided herein are methods of using the same or compositions thereof for therapeutic treatment of cancers (e.g., hematological cancers or solid tumor cancers).

Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.

Abstract: The present application relates to compositions for preventing or treating viral and other microbial infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a pathogen that infects through a mucosa, and a positively charged mucoadhesive peptide fragment. Also provided are antibodies and constructs thereof that specifically binds to an S1 subunit of a spike protein of SARS-CoV-2. Compositions comprising the chimeric proteins, antibodies, or constructs described herein are useful for preventing or treating a microbial infection in an individual, such as a coronavirus infection.