Abstract: The present application provides methods of enhancing T cell function (e.g., expansion, persistence and/or effector functions), particularly by genetic modification of the Regnase-1, Batf, and additional genes (alone or in combination). The application also provides modified T cells manufactured using the methods provided by this invention and related pharmaceutical compositions. The application further provides methods of using the modified T cells for treating a disease (e.g., a cancer or an infectious disease).

Abstract: The present application is directed to a display device and an over-voltage protection method. As an example, the display device includes a power source assembly and an electric load. The power source assembly includes an LLC circuit, a transformer and a feedback circuit. An input end of the transformer is connected with a control end of the LLC circuit, a first output end of the transformer is connected with a supply end of the LLC circuit, a second output end of the transformer is connected with the electric load, and the transformer is configured to supply power to the LLC circuit and the electric load. A first end of the feedback circuit is connected with the second output end of the transformer, a second end of the feedback circuit is connected with the feedback end of the LLC circuit and the feedback circuit is configured to supply a voltage derived from the second output end of the transformer to the LLC circuit.

Abstract: The present application is directed to a display device and an over-voltage protection method. As an example, the display device includes a power source assembly and an electric load. The power source assembly includes an LLC circuit, a transformer and a feedback circuit. An input end of the transformer is connected with a control end of the LLC circuit, a first output end of the transformer is connected with a supply end of the LLC circuit, a second output end of the transformer is connected with the electric load, and the transformer is configured to supply power to the LLC circuit and the electric load. A first end of the feedback circuit is connected with the second output end of the transformer, a second end of the feedback circuit is connected with the feedback end of the LLC circuit and the feedback circuit is configured to supply a voltage derived from the second output end of the transformer to the LLC circuit.

Abstract: An LED backlight source drive circuit, an LED backlight source and a liquid crystal display device are provided. LED backlight source drive circuit includes a voltage input terminal, a coupling module, and a rectifier module. The coupling module is connected to the voltage input terminal for receiving a current complying with a total working voltage of two power consumption modules from the voltage input terminal, and converting the current into a current complying with a working voltage of one power consumption module. The rectifier module is connected to the coupling module for inputting the current complying with the working voltage of one power consumption module into two serially-connected power consumption modules, thereby supplying power to the power consumption modules. The LED backlight source and the liquid crystal display device include two power consumption modules and the above LED backlight source drive circuit.

Abstract: An LED backlight source drive circuit, an LED backlight source and a liquid crystal display device are provided. LED backlight source drive circuit includes a voltage input terminal, a coupling module, and a rectifier module. The coupling module is connected to the voltage input terminal for receiving a current complying with a total working voltage of two power consumption modules from the voltage input terminal, and converting the current into a current complying with a working voltage of one power consumption module. The rectifier module is connected to the coupling module for inputting the current complying with the working voltage of one power consumption module into two serially-connected power consumption modules, thereby supplying power to the power consumption modules. The LED backlight source and the liquid crystal display device include two power consumption modules and the above LED backlight source drive circuit.