Patents by Inventor Hongbo Qi

Hongbo Qi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Zwitterionic tachykinin receptor antagonists
    Patent number: 6479518
    Abstract: The present invention is directed to certain novel compounds represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R12, R13, Q, W, X, Y and Z are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of psychiatric disorders including depression and anxiety.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: November 12, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Paul E. Finke, Laura C. Meurer, Sander G. Mills, Malcolm MacCoss, Hongbo Qi
  • Zwitterionic tachykinin receptor antagonists
    Publication number: 20020042431
    Abstract: The present invention is directed to certain novel compounds represented by structural formula I: 1
    Type: Application
    Filed: September 21, 2001
    Publication date: April 11, 2002
    Inventors: Paul E. Finke, Laura C. Meurer, Sander G. Mills, Malcolm MacCoss, Hongbo Qi
  • Trypthophan ureas as neurokinnin antagonists
    Patent number: 5869489
    Abstract: Disclosed are Substituted azacycles of formula I ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.
    Type: Grant
    Filed: March 11, 1997
    Date of Patent: February 9, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Shrenik K. Shah, Hongbo Qi, Malcolm Maccoss
  • Spiro-substituted azacycles as tachykinin receptor antagonists
    Patent number: 5869496
    Abstract: Disclosed are spiro-substituted azacycles of formula (I), are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, emesis and asthma. In particular compounds of formula (I) are shown to be neurokinin antagonists.
    Type: Grant
    Filed: July 11, 1995
    Date of Patent: February 9, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Jeffrey J. Hale, Malcolm Maccoss, Sander G. Mills, Hongbo Qi, Shrenik K. Shah