Abstract: A substrate processing apparatus includes a chamber configure to provide a space for processing a substrate, a substrate support configured to support the substrate in the chamber, an upper supply port provided in an upper portion of the chamber and configured to supply a supercritical fluid on an upper surface of the substrate, a recess provided in an upper wall of the chamber and having a diffuser shape whose diameter gradually increases from an outlet of the upper supply port, and a fluidic baffle disposed in the recess between the upper supply port and the substrate and including unit cells repeatedly arranged in a space with same phases and geometric sizes and in fluid communication with each other.

Abstract: The present invention provides retrovirus-specific oligonucleotides and a method for measuring retroviral titer using same as primers in polymerase chain reaction (PCR). As the inventive method makes it possible to rapidly quantify measure retroviral DNA inserted into the genome of a target cell or the presence of retroviral RNA in a solution, it can be effectively used in the measurement of retroviral vector for gene therapy, the detection of replication competent retrovirus (RCR) in the sera of a subject receiving gene therapy, or the diagnosis of wild-type retrovirus.