Patents by Inventor Hongchang Ma

Hongchang Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Local enhancement for a medical image
    Patent number: 11617553
    Abstract: The present disclosure relates to locally enhancing medical images. In accordance with certain embodiments, a method includes determining a boundary of a region of interest in a displayed medical image, overlaying the boundary on the displayed medical image, adjusting a position of a collimator of a medical imaging system based on the determined boundary, enhancing image quality of the region of interest, and displaying the enhanced region of interest within the boundary.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: April 4, 2023
    Assignee: GE Precision Healthcare LLC
    Inventors: James Zhengshe Liu, Xiaosong Liu, Longjiang Yu, HongChang Ma, Jan D. Bruening, Todd W. Brown
  • LOCAL ENHANCEMENT FOR A MEDICAL IMAGE
    Publication number: 20230050772
    Abstract: The present disclosure relates to locally enhancing medical images. In accordance with certain embodiments, a method includes determining a boundary of a region of interest in a displayed medical image, overlaying the boundary on the displayed medical image, adjusting a position of a collimator of a medical imaging system based on the determined boundary, enhancing image quality of the region of interest, and displaying the enhanced region of interest within the boundary.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 16, 2023
    Inventors: James Zhengshe Liu, Xiaosong Liu, Longjiang Yu, HongChang Ma, Jan D. Bruening, Todd W. Brown
  • Crystal structure of the c-fms kinase domain: applications and use of heterologous substitutions of kinase insert domains for crystallization
    Publication number: 20060094081
    Abstract: The present invention includes a crystal structure of the kinase domain of c-fms and a methodology to produce diffraction quality crystals of the c-fms kinase domain by heterologous substitution of the kinase insert domain. Also included in the invention is the structure of the c-fms kinase domain in liganded form for use in the discovery of inhibitors of c-fms for the treatment of diseases caused by inappropriate activity of c-fms. The present invention includes descriptions of the X-ray diffraction patterns of the crystals. The diffraction patterns allow the three dimensional structure of c-fms to be determined at atomic resolution so that ligand binding sites on can be identified and the interactions of ligands with amino acid residues can be modeled.
    Type: Application
    Filed: October 20, 2005
    Publication date: May 4, 2006
    Inventors: Carsten Schubert, Barry Springer, Ingrid Deckman, Raymond Patch, Geoffrey Struble, Hongchang Ma, Celine Schalk-Hihi, Benjamin Brandt, Ioanna Petrounia
  • Transcription and gene expression regulators
    Patent number: 6559354
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a transcription or gene expression regulator. The invention also relates to the construction of a chimeric gene encoding all or a portion of the transcription or gene expression regulator, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the transcription or gene expression regulator in a transformed host cell.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: May 6, 2003
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Hongchang Ma, Omolayo O. Famodu nee Morakinyo, Joan T. Odell, Emil M. Orozco, Jr., J. Antoni Rafalski