Abstract: The present disclosure provides a structured nucleic acid particle comprising a scaffold strand and a plurality of staple strands hybridized to the scaffold, forming a structured nucleic acid particle having a first planar structure coupled to a first protruding structure extending from a face of the first planar structure. Also, the present disclosure provides a structured nucleic acid particle comprising a scaffold strand and a plurality of staple strands hybridized to the scaffold, forming a structured nucleic acid particle having a plurality of planar faces. In some instances, the structured nucleic acid particle has six planar faces.

Abstract: Methods and systems are provided for forming arrays of analytes, in which the arrays are characterized by a high site occupancy and optionally a low site co-occupancy, and in which the arrays are configured for single-analyte processes. Methods for effecting transport of binding entities to array sites are also provided.

Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.