Patents by Inventor Hongjie Li

Hongjie Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250186583
    Abstract: The present application provides a fusion protein, a method for preparing such fusion proteins and use thereof. The fusion protein comprises a Fab fragment capable of binding specifically to 4-lBB molecules and comprises CD40L capable of binding specifically to CD40 molecules; the N-terminus of the first CD40L is connected to the C-terminus of the light chain or heavy chain of the Fab fragment by means of a first peptide linker. The fusion protein of the CD137 antibody and CD40L of the present application is capable of binding specifically to CD40, has the effects of inducing dendritic cell maturation, activating lymphocytes, etc., and can be used for treating tumors and immune-related diseases; Meanwhile, the fusion protein of the CD137 antibody and CD40L can target 4-lBB and activate the signal transduction pathway of 4-lBB to enhance immune responses.
    Type: Application
    Filed: February 15, 2023
    Publication date: June 12, 2025
    Inventors: Yujie LIU, Xin GAO, Niliang QIAN, Guili XU, Jingjing WANG, Hongjie LI, Cuima YANG, Liting CHEN
  • Patent number: 12234325
    Abstract: A resin composition, comprising: a modified maleimide resin (A), an active ester resin (B), and an epoxy resin (C); the modified maleimide resin (A) is obtained by means of reacting a maleimide compound (M) having at least two maleimide groups/molecules with an amine compound (N1) having at least one primary amine group/molecule and an amine compound (N2) having at least two primary amine groups/molecules, and the molecular weight distribution is: molecules having a molecular weight between 1000 and 4500 account for 25-60% the total number of molecules.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: February 25, 2025
    Assignee: SHENGYI TECHNOLOGY CO., LTD.
    Inventors: Hongjie Li, Junqi Tang
  • Publication number: 20240352139
    Abstract: The present application provides a fusion protein, containing: an anti-CD137 antibody capable of specifically binding to a CD137 molecule or an antigen binding fragment thereof; an anti-CD3 antibody capable of specifically binding to a CD3 molecule or an antigen binding fragment thereof; and a first peptide linker and a second peptide linker. The present application also provides a nucleic acid encoding the fusion protein, an expression vector containing the nucleic acid, a host cell containing the nucleic acid or the expression vector, a method for preparing the fusion protein, a pharmaceutical composition containing the fusion protein, and a use of the fusion protein.
    Type: Application
    Filed: November 11, 2021
    Publication date: October 24, 2024
    Inventors: Xin GAO, Niliang QIAN, Xiujie PAN, Guili XU, Yujie LIU, Hongjie LI, Cuima YANG, Qinzhi XU, Xiaoqian DOU, Yunhui LIU, Zhenjun YU, Guijun BAI
  • Publication number: 20240046672
    Abstract: A target detection method includes inputting a to-be-detected image into a backbone included in a target detection model to determine that an output of the backbone is a feature corresponding to the to-be-detected image and inputting the feature corresponding to the to-be-detected image into a prediction head included in the target detection model to determine that an output of the prediction head is target information included in the to-be-detected image. The target information included in the to-be-detected image includes at least one of position information, size information, orientation information, depth information, or blocking information of a target in the to-be-detected image. The target detection model is trained and obtained based on a sample image including a target sub-area and a non-target sub-area.
    Type: Application
    Filed: January 25, 2023
    Publication date: February 8, 2024
    Inventor: Hongjie LI
  • Publication number: 20230384359
    Abstract: Provided are a device and a method for live detecting a partial discharge of an overhead line in a distribution network and equipment along the line, including: acquiring a second synchronous pulse signal and a first partial discharge signal via a master detection unit; acquiring a first synchronous pulse signal and a second partial discharge signal via a slave detection unit; analyzing the second synchronous pulse signal and the first synchronous pulse signal via a main control computer to obtain time data; and calculating a propagation time based on the time data, synchronously processing the time data based on the propagation time to obtain reference zeros, and calculating a partial discharge location according to the first partial discharge signal and the second partial discharge signal based on the reference zeros.
    Type: Application
    Filed: May 23, 2023
    Publication date: November 30, 2023
    Inventors: Yuan YAN, Hongjie LI, Lei JIN, Yinsong ZHAO
  • Publication number: 20230097451
    Abstract: A display panel, a touch display device, and a method for manufacturing a touch display device are provided in the present disclosure. The display panel includes a display area and a non-display area adjacent to the display area. The display panel includes a first substrate and a second substrate disposed opposite to each other; a first narrow border sealant located in the non-display area, and a liquid crystal layer located in the display area disposed between the first substrate and the second substrate; and a first reflective layer disposed on at least one side of the first narrow border sealant.
    Type: Application
    Filed: August 3, 2020
    Publication date: March 30, 2023
    Inventors: Dongchen HUANG, Chingyuan CHENG, Hongji LI, Yuexia LIN
  • Patent number: 11513374
    Abstract: The present invention provides a display panel and a display device. The display panel includes an array substrate, a color film substrate disposed on the array substrate, and a photochromic glass layer disposed on the color film substrate. A color change region is formed when an ultraviolet laser irradiates the photochromic glass layer, and the color change region filters passing lights. The display panel further includes a plurality of scattered particles distributed on the photochromic glass layer.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: November 29, 2022
    Assignee: HUIZHOU CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Dongchen Huang, Yuexia Lin, Hongji Li
  • Publication number: 20220227942
    Abstract: A resin composition, comprising: a modified maleimide resin (A), an active ester resin (B), and an epoxy resin (C); the modified maleimide resin (A) is obtained by means of reacting a maleimide compound (M) having at least two maleimide groups/molecules with an amine compound (N1) having at least one primary amine group/molecule and an amine compound (N2) having at least two primary amine groups/molecules, and the molecular weight distribution is: molecules having a molecular weight between 1000 and 4500 account for 25-60% the total number of molecules.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 21, 2022
    Inventors: Hongjie LI, Junqi TANG
  • Publication number: 20210124192
    Abstract: The present invention provides a display panel and a display device. The display panel includes an array substrate, a color film substrate disposed on the array substrate, and a photochromic glass layer disposed on the color film substrate. A color change region is formed when an ultraviolet laser irradiates the photochromic glass layer, and the color change region filters passing lights. The display panel further includes a plurality of scattered particles distributed on the photochromic glass layer.
    Type: Application
    Filed: November 8, 2019
    Publication date: April 29, 2021
    Inventors: Dongchen HUANG, Yuexia LIN, Hongji LI
  • Patent number: 10904064
    Abstract: Communication method and base stations are provided. One example includes determining, by a base station, that co-channel interference exists. For N consecutive symbols before a guard period (GP) in a special subframe in a radio frame, the base station sends a signal by using M1 middle resource blocks (RBs) of the N symbols, and reserves use of an RB other than the M1 RBs in the N symbols, where both N and M1 are positive integers.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: January 26, 2021
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Xinyu Wang, Ding Ding, Boyun Xie, Hongjie Li, Xing Huang
  • Patent number: 10518342
    Abstract: Hydraulic two-side rolling-cut shears, including: a front transport roller device, a rear transport roller device, a shear body, and a roller carrier. The front transport roller device includes a laser scriber, a magnetic alignment device, and a pinch roller device. The rear transport roller device includes a vertical guide roller. The laser scriber is disposed on the front end of the front transport roller device. The magnetic alignment device is disposed in the middle part of the front transport roller device. The pinch roller device is disposed on the rear end of the front transport roller device in front of the shear body. The roller carrier is disposed longitudinally in the middle of the shear body. The vertical guide roller is disposed on the rear transport roller device and behind the shear body.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: December 31, 2019
    Assignee: TAIYUAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qingxue Huang, Lifeng Ma, Jinli Meng, Zhibing Chu, Heyong Han, Hongjie Li, Yugui Li
  • Publication number: 20190372352
    Abstract: The present disclosure provides a method for controlling a solar energy system. The method includes: receiving component control information sent by an external control system, and executing a control operation corresponding to the component control information on a solar energy component connected to a junction box according to the component control information. A device for controlling a solar energy system, a central controller and a solar energy system are also provided.
    Type: Application
    Filed: September 20, 2018
    Publication date: December 5, 2019
    Inventors: Ya'nan XIAO, Wei PAN, Haifeng LI, Hongjie LI
  • Patent number: 10410292
    Abstract: The provided method includes: classifying damage assessing images of a same vehicle portion into one same image set; obtaining keypoint features of each image set, diving every two damage assessing images in each image set into one image group, matching multiple relevant keypoints from the damage assessing images in each image group; calculating a feature point transform matrix of each image, and converting one of the two damage assessing images in each image group to a to-be-verified image which has the same shooting angle as the other damage assessing image in the image group; matching feature parameters of the to-be-verified image with those of the other damage assessing image in the same image group; and generating reminder information, when there are unmatched parameters, to remind the user of frauds of the damage assessing images received from the terminal.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: September 10, 2019
    Assignee: Ping An Technology (Shenzhen) Co., Ltd.
    Inventors: Jianzong Wang, Hongjie Li, Jing Xiao
  • Publication number: 20190207798
    Abstract: Communication method and base stations are provided. One example includes determining, by a base station, that co-channel interference exists. For N consecutive symbols before a guard period (GP) in a special subframe in a radio frame, the base station sends a signal by using M1 middle resource blocks (RBs) of the N symbols, and reserves use of an RB other than the M1 RBs in the N symbols, where both N and M1 are positive integers.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Inventors: Xinyu WANG, Ding DING, Boyun XIE, Hongjie LI, Xing HUANG
  • Patent number: D980439
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: March 7, 2023
    Inventor: Hongji Li
  • Patent number: D982172
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: March 28, 2023
    Inventor: Hongji Li
  • Patent number: D984658
    Type: Grant
    Filed: November 1, 2022
    Date of Patent: April 25, 2023
    Inventor: Hongji Li
  • Patent number: D985146
    Type: Grant
    Filed: October 4, 2022
    Date of Patent: May 2, 2023
    Inventor: Hongji Li
  • Patent number: D1036681
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: July 23, 2024
    Inventor: Hongji Li
  • Patent number: D1050575
    Type: Grant
    Filed: May 9, 2023
    Date of Patent: November 5, 2024
    Assignee: Yixing Mei Sheng Microelectronics Technology Co., Ltd.
    Inventors: Jinong Zhao, Hongjie Li, Huaqiang Zhao, Weiguo Chen