Patents by Inventor Hongjie Pan

Hongjie Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250197490
    Abstract: Disclosed herein are antibodies and antigen-binding fragments thereof that specifically bind to corticotropin-releasing hormone (CRH). Also disclosed are methods and pharmaceutical compositions containing such antibodies and antigen-binding fragments, and the use of said anti-corticotropin-releasing hormone (CRH) antibodies and antigen-binding fragments thereof in treating congenital adrenal hyperplasia (CAH) and related disorders.
    Type: Application
    Filed: August 5, 2022
    Publication date: June 19, 2025
    Applicant: HBM ALPHA THERAPEUTICS, INC.
    Inventors: Joseph A. MAJZOUB, Lile LIU, Hongjie PAN, Qiang LV, Frank GROSVELD, Dubravka DRABEK, Rien VAN HAPEREN, Xiaoxiao WANG, Yun HE, Yongqiang WANG, Jin HUANG, Jung LEE, Jiuqiao ZHAO
  • Publication number: 20250154268
    Abstract: Disclosed in the present invention is an antibody targeting CD25 or a variant thereof. A monoclonal antibody targeting CD25 is a naturally occurring antibody, has an activity of binding to human CD25 and cynomolgus monkey CD25, and has a stronger ADCC effect after being modified with Fc. In-vitro experiments show that the antibody has the effect of clearing Treg and lymphoma cells without blocking an IL-2 signaling pathway.
    Type: Application
    Filed: January 16, 2023
    Publication date: May 15, 2025
    Inventors: Qiuming PAN, Chengen WANG, Jinqiu HE, Yan LI, Yuandong WANG, Yongqiang WANG, Chuchu ZHAO, Hongjie PAN, Yiping RONG, Haishan LUO
  • Patent number: D1001399
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: October 10, 2023
    Inventor: Hongjie Pan
  • Patent number: D1011656
    Type: Grant
    Filed: October 17, 2023
    Date of Patent: January 16, 2024
    Inventor: Hongjie Pan