Patents by Inventor Hongju Zhou

Hongju Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE SILENCING VIA GENOME EDITING
    Publication number: 20220010322
    Abstract: The present invention relates to methods and compositions for gene silencing by genome editing. In some embodiments, nucleases are provided selected from the group consisting of meganucleases (MNs), zinc-finger nucleases (ZFNs), transcription-activator like effector nucleases (TALENs), Cas9 nuclease, Cfp1 nuclease, dCas9-FokI, dCpf1-FokI, chimeric Cas9/Cpf1-cytidine deaminase, chimeric Cas9/Cpf1-adenine deaminase, chimeric FEN1-FokI, and Mega-TALs, a nickase Cas9 (nCas9), chimeric dCas9 non-FokI nuclease and dCpf1 non-FokI nuclease. Additionally, the present invention relates to methods and compositions for gene silencing by genome editing. Also provided are methods and compositions for rearranging a chromosome by genome editing.
    Type: Application
    Filed: November 26, 2019
    Publication date: January 13, 2022
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Jian LV, Xi CHEN, Kun YU, Dawei LIANG, Hongju ZHOU, Jianping XU
  • NOVEL WHEAT CENH3 ALLELES
    Publication number: 20210378192
    Abstract: The present invention relates to wheat plants comprising a mutation causing an alteration of the amino acid sequence in centromere histone H3 (CENH3), which have the biological activity of a haploid inducer. Further, the present invention provides methods of generating the wheat plants of the present invention and haploid and doubled haploid wheat plants obtainable by crossing the wheat plants of the present invention with wildtype wheat plants.
    Type: Application
    Filed: October 10, 2019
    Publication date: December 9, 2021
    Applicant: Syngenta Crop Protection AG
    Inventors: Jain LV, Kun YU, Juan WEI, Chunxia Liu, Hongju Zhou, Timothy Joseph Kelliher