Patents by Inventor Hongjuan Zhao
Hongjuan Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220059877Abstract: The embodiment claims an electrode assembly, its manufacturing method and battery cell made of such. The assembly unit from the top to bottom integrates first electrode plate, first separator plate, second electrode plate, second separator plate and another first electrode plate. The polarity of the first and second electrode plate is opposite to each other. The edges of the first and second separator plates join on one side forming U shape structure. The electrode assembly in this embodiment is a unit for multiple stacking of such to form the internal structure of a battery cell. Such design offers improved efficiency in cell manufacturing and achieves accurate alignments between positive and negative electrodes. The assembly unit upon numerous stacking would ensure overall alignments of positive and negative electrodes for cell quality improvement.Type: ApplicationFiled: December 13, 2018Publication date: February 24, 2022Applicant: Do Fluoride Jiaozuo New Energy Tech Co LtdInventors: Pan Wang, Hongtao Ma, Fei Xu, Yongfeng Zhao, Xingfu Liu, Hongjuan Zhao, Huifang Zhao, Yu Ma, Jing Zhao
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Patent number: 10745564Abstract: The present disclosure discloses a dye for industrialization of dyeing cotton fiber in supercritical carbon dioxide that can react with cotton fiber, wherein a preparation method therefor comprises the following steps: dissolving a hydroxyl-containing natural dye in an organic solvent, dropwise adding an alcohol compound containing a halogen group into a reaction system in the presence of an acid-binding agent, precipitating the product with another solvent after the reaction is completed, and then filtrating and drying to obtain the compound described. The obtained compound is used for dyeing cotton fiber in supercritical carbon dioxide. The dye provided by the present disclosure is capable of dyeing cotton fiber in supercritical carbon dioxide conditions, and has a better color fastness while dyeing the cotton fiber.Type: GrantFiled: October 19, 2017Date of Patent: August 18, 2020Assignee: DALIAN POLYTECHNIC UNIVERSITYInventors: Hongjuan Zhao, Laijiu Zheng, Huanda Zheng, Jun Yan, Xiaoqing Xiong, Miao Liu, Ju Wei
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Publication number: 20190233650Abstract: The present disclosure discloses a dye for industrialization of dyeing cotton fiber in supercritical carbon dioxide that can react with cotton fiber, wherein a preparation method therefor comprises the following steps: dissolving a hydroxyl-containing natural dye in an organic solvent, dropwise adding an alcohol compound containing a halogen group into a reaction system in the presence of an acid-binding agent, precipitating the product with another solvent after the reaction is completed, and then filtrating and drying to obtain the compound described. The obtained compound is used for dyeing cotton fiber in supercritical carbon dioxide. The dye provided by the present disclosure is capable of dyeing cotton fiber in supercritical carbon dioxide conditions, and has a better color fastness while dyeing the cotton fiber.Type: ApplicationFiled: October 19, 2017Publication date: August 1, 2019Inventors: Hongjuan ZHAO, Laijiu ZHENG, Huanda ZHENG, Jun YAN, Xiaoqing XIONG, Miao LIU, Ju WEI
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Patent number: 10005829Abstract: The invention relates to novel compositions comprising modified apelin-13 peptide sequences designed to treat cardiovascular disease in subjects to whom they are administered, and which exhibit greater resistance to degradation, and equivalent or greater bioactivity than their wild type counterparts. The invention also relates to methods of making said compositions and using said compositions as pharmaceutically active agents to treat cardiovascular disease.Type: GrantFiled: November 19, 2013Date of Patent: June 26, 2018Assignee: NOVARTIS AGInventors: Frederic Zecri, Kayo Yasoshima, Philipp Grosche, Jun Yuan, Hongjuan Zhao
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Patent number: 9982017Abstract: The invention provides a synthetic polypeptide of Formula I?: or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia.Type: GrantFiled: May 18, 2015Date of Patent: May 29, 2018Assignee: NOVARTIS AGInventors: Frederic Zecri, Andrei Golosov, Philipp Grosche, Hongjuan Zhao, Qi-Ying Hu, Hidetomo Imase
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Patent number: 9908919Abstract: The invention provides a synthetic polypeptide of Formula I (SEQ ID NO: 1): X1-R-X3-R-L-X6-X7-K-X9-P-X11-X12-X13??I or an amide, an ester, a salt thereof, or a bioconjugate thereof, wherein X1, X3, X6, X7, X9, X11, X12 and X13 are defined herein. The polypeptides and bioconjugates are agonist of the APJ receptor.Type: GrantFiled: July 21, 2014Date of Patent: March 6, 2018Assignee: NOVARTIS AGInventors: Frederic Zecri, Philipp Grosche, Kayo Yasoshima, Hongjuan Zhao, Jun Yuan
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Patent number: 9851259Abstract: Methods, systems, and apparatus, for an infrared detector are provided. In one aspect, an infrared detector is provided that includes a pyroelectric sensor; a controller for receiving a trigger signal outputted by the pyroelectric sensor; a thermopile sensor, wherein the controller starts the thermopile sensor after receiving the trigger signal output by the pyroelectric sensor; and an alarm, wherein the controller controls the alarm to generate an alarm signal in response to a determination that a difference between a current temperature and a background temperature detected by the thermopile sensor is larger than a threshold value and a determination that the areas of the thermopile sensor activated correspond to a human being.Type: GrantFiled: August 15, 2016Date of Patent: December 26, 2017Assignee: MivaLife Mobile Technology, Inc.Inventors: Hongjuan Zhao, Yueqiong Wang, Kai Li, Hangqiang Chen, Shangyu Guo, Shaodong Ma, Qin Yuan
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Publication number: 20170233443Abstract: The invention provides a cyclic polypeptide of Formula I (SEQ ID NO: 1): X1-R-X3-X4-L-S-X7-X8-X9-X10-X11-X12-X13??I or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein X1, X3, X4, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor.Type: ApplicationFiled: April 25, 2017Publication date: August 17, 2017Inventors: Alexandra Marshall BRUCE, Philipp GROSCHE, Carla GUIMARAES, Aaron KANTER, Changgang LOU, Aimee Richardson USERA, Kayo YASOSHIMA, Jun YUAN, Frederic Zecri, Hongjuan ZHAO
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Patent number: 9683018Abstract: The invention provides a synthetic polypeptide of Formula I?: X1-R-P-R-X5-X6-X7-K-X9-P-X11-X12-X13 or an amide, an ester, a salt or a bioconjugate thereof, wherein X1, X5, X6, X7, X9 and X11 to X13 are defined herein. The polypeptides and bioconjugates are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides or bioconjugates of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia.Type: GrantFiled: July 21, 2014Date of Patent: June 20, 2017Assignee: NOVARTIS AGInventors: Frederic Zecri, Philipp Grosche, Kayo Yasoshima, Hongjuan Zhao, Jun Yuan
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Patent number: 9683019Abstract: The invention provides a cyclic polypeptide of Formula I (SEQ ID NO: 1): X1-R-X3-X4-L-S-X7-X8-X9-X10-X11-X12-X13??I or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein X1, X3, X4, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor.Type: GrantFiled: December 9, 2015Date of Patent: June 20, 2017Assignee: NOVARTIS AGInventors: Frederic Zecri, Philipp Grosche, Kayo Yasoshima, Hongjuan Zhao, Jun Yuan, Aimee Richardson Usera, Changgang Lou, Aaron Kanter, Alexandra Marshall Bruce, Carla Guimaraes
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Publication number: 20170160140Abstract: Methods, systems, and apparatus, for an infrared detector are provided. In one aspect, an infrared detector is provided that includes a pyroelectric sensor; a controller for receiving a trigger signal outputted by the pyroelectric sensor; a thermopile sensor, wherein the controller starts the thermopile sensor after receiving the trigger signal output by the pyroelectric sensor; and an alarm, wherein the controller controls the alarm to generate an alarm signal in response to a determination that a difference between a current temperature and a background temperature detected by the thermopile sensor is larger than a threshold value and a determination that the areas of the thermopile sensor activated correspond to a human being.Type: ApplicationFiled: August 15, 2016Publication date: June 8, 2017Applicant: MivaLife Mobile Technology, Inc.Inventors: Hongjuan Zhao, Yueqiong Wang, Kai Li, Hangqiang Chen, Shangyu Guo, Shaodong Ma, Qin Yuan
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Patent number: 9418532Abstract: Methods, systems, and apparatus, for an infrared detector are provided. In one aspect, an infrared detector is provided that includes a pyroelectric sensor; a controller for receiving a trigger signal outputted by the pyroelectric sensor; a thermopile sensor, wherein the controller starts the thermopile sensor after receiving the trigger signal output by the pyroelectric sensor; and an alarm, wherein when the thermopile sensor determines that a difference between a current temperature and a background temperature is larger than a threshold value, the controller controls the alarm to generate an alarm signal.Type: GrantFiled: September 19, 2014Date of Patent: August 16, 2016Assignee: MivaLife Mobile Technology, Inc.Inventors: Hongjuan Zhao, Yueqiong Wang, Kai Li, Hangqiang Chen, Shangyu Guo, Shaodong Ma, Qin Yuan
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Publication number: 20160166634Abstract: The invention provides a bioconjugates comprising a synthetic polypeptide of Formula I? (SEQ ID NO: 1): or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein and a half-life extending moiety wherein the peptide and the half-life extending moiety are covalently linked or fuse, optionally via a linker. The polypeptides are agonist of the APJ receptor.Type: ApplicationFiled: February 25, 2016Publication date: June 16, 2016Applicant: NOVARTIS AGInventors: Shari Lynn CAPLAN, Andrei GOLOSOV, Philipp GROSCHE, Carla GUIMARAES, Aaron KANTER, Changgang LOU, David Thomas PARKER, Eric C. Peters, Aimee Richardson USERA, Kayo YASOSHIMA, Jun YUAN, Federic ZECRI, Hongjuan ZHAO
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Publication number: 20160159871Abstract: The invention provides a synthetic polypeptide of Formula I?: X1-R-X3-R-L-X6-X7-K-X9-P-X11-X12-X13 or an amide, an ester, a salt thereof, or a bioconjugate thereof, wherein X1, X3, X6, X7, X9, X11, X12 and X13 are defined herein. The polypeptides and bioconjugates are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides and bioconjugates of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia.Type: ApplicationFiled: July 21, 2014Publication date: June 9, 2016Applicant: Novartis AGInventors: Frédéric ZECRI, Philipp GROSCHE, Kayo YASOSHIMA, Hongjuan ZHAO, Jun YUAN
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Publication number: 20160145309Abstract: The invention provides a synthetic polypeptide of Formula I?: X1-R-P-R-X5-X6-X7-K-X9-P-X11-X12-X13 or an amide, an ester, a salt or a bioconjugate thereof, wherein X1, X5, X6, X7, X9 and X11 to X13 are defined herein. The polypeptides and bioconjugates are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides or bioconjugates of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia.Type: ApplicationFiled: July 21, 2014Publication date: May 26, 2016Applicant: NOVARTIS AGInventors: Frédéric ZECRI, Philipp GROSCHE, Kayo YASOSHIMA, Hongjuan ZHAO, Jun YUAN
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Patent number: 9340582Abstract: The invention provides a bioconjugates comprising a synthetic polypeptide of Formula I? (SEQ ID NO: 1): or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein and a half-life extending moiety wherein the peptide and the half-life extending moiety are covalently linked or fuse, optionally via a linker. The polypeptides are agonist of the APJ receptor.Type: GrantFiled: July 21, 2014Date of Patent: May 17, 2016Assignee: NOVARTIS AGInventors: Jun Yuan, Frederic Zecri, Philipp Grosche, Hongjuan Zhao, Eric Peters, Shari Lynn Caplan, Changgang Lou
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Publication number: 20160108091Abstract: The invention provides a cyclic polypeptide of Formula I (SEQ ID NO: 1): X1-R-X3-X4-L-S-X7-X8-X9-X10-X11-X12-X13??I or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein X1, X3, X4, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor.Type: ApplicationFiled: December 9, 2015Publication date: April 21, 2016Applicant: NOVARTIS AGInventors: Frederic ZECRI, Philipp GROSCHE, Kayo YASOSHIMA, Hongjuan ZHAO, Jun YUAN, Aimee Richardson USERA, Changgang LOU, Aaron KANTER, Alexandra Marshall BRUCE, Carla GUIMARAES
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Publication number: 20160093187Abstract: The sound wave and temperature sensor of the present disclosure can be used for detecting whether a fire accident occurs within a specific area without risking altering or damaging existing sensors, and can be a part of an intelligent home security system. One aspect is to provide an integrated sound wave and temperature sensor that can efficiently work together with the existing sensors. An example apparatus can include a sound sensor, a temperature sensor, a communication circuit, and a microcontroller. The microcontroller can be configured to, responsive to the sound sensor detecting an audible alarm emitted from an environmental detector, determine whether an ambient temperature exceeds a threshold value. Further, the microcontroller can, responsive to both the sound sensor detecting the audible alarm and the ambient temperature exceeding a threshold value, cause the communication circuit to transmit an alert to a recipient.Type: ApplicationFiled: September 25, 2015Publication date: March 31, 2016Inventors: Junmin Zhang, Xiang Yan, Yanyuan Huang, Hongjuan Zhao, Guohua Zhang, Zhanmin Wu, Qin Yuan
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Patent number: 9266925Abstract: The invention provides a cyclic polypeptide of Formula I (SEQ ID NO: 1): X1-R-X3-X4-L-S-X7-X8-X9-X10-X11-X12-X13??I or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein X1, X3, X4, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor.Type: GrantFiled: July 21, 2014Date of Patent: February 23, 2016Assignee: NOVARTIS AGInventors: Frederic Zecri, Philipp Grosche, Kayo Yasoshima, Hongjuan Zhao, Jun Yuan, Aimee Richardson Usera, Changgang Lou, Aaron Kanter, Alexandra Marshall Bruce, Carla Giumaraes
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Publication number: 20150284446Abstract: The invention relates to novel compositions comprising modified apelin-13 peptide sequences designed to treat cardiovascular disease in subjects to whom they are administered, and which exhibit greater resistance to degradation, and equivalent or greater bioactivity than their wild type counterparts. The invention also relates to methods of making said compositions and using said compositions as pharmaceutically active agents to treat cardiovascular disease.Type: ApplicationFiled: November 19, 2013Publication date: October 8, 2015Applicant: NOVARTIS AGInventors: Frédéric ZECRI, Kayo YASOSHIMA, Philipp GROSCHE, Jun YUAN, Hongjuan ZHAO