Patents by Inventor Hongjun Liang
Hongjun Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240112283Abstract: The present disclosure provides an ecological governance method based on erosion prevention and control for a gentle slope farmland and relates to the technical field of ecological governance of farmlands. The ecological governance method based on erosion prevention and control for a gentle slope farmland includes the following steps: sampling a gentle slope farmland to investigate erosion thereof; and determining erosion of a gentle slope cultivated land and selecting a corresponding recovery strategy based on a detection result of a sample, a soil quality index (SQI), and a comprehensive vegetation quality index (VQI), where the recovery strategy includes a natural recovery method and a biological-farming comprehensive recovery method; enclosing the gentle slope cultivated land, fallowing the gentle slope cultivated land and reducing tillage; exterminating insect pests and poisonous weeds in the enclosed area; and turning over straws under soil by a cultivator. The growth of poisonous weeds is inhibited.Type: ApplicationFiled: September 21, 2023Publication date: April 4, 2024Inventors: Weiping Yan, Shaofeng Bian, Yongjun Wang, Hongxiang Zhao, Lihua Zhang, Baoyu Chen, Hongjun Wang, Tiehua Cao, Xuanhe Liang, Guobo Tan, Ning Sun, Chen Xu, Fei Li, Xiangmeng Meng, Jinghua Wang, Qingge Wang
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Patent number: 11937444Abstract: Provided are a flexible display substrate, a display panel, a display device, and a manufacturing method, relating to the technical field of display. The flexible display substrate is provided with a first bonding and a second bonding region. The first bonding region and the second bonding region are configured to be bonded to an electronic component, and a thickness of the flexible display substrate in the first bonding region is greater than a thickness of the flexible display substrate in the second bonding region in a direction perpendicular to the flexible display substrate.Type: GrantFiled: March 19, 2020Date of Patent: March 19, 2024Assignees: CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Hongjun Zhou, Hengzhen Liang
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Patent number: 11936571Abstract: Examples described herein relate to offload reliable transport management to a network interface device and store packets to be resent, based on received packet receipt acknowledgements (ACKs), into one or more kernel space queues that are also accessible in user space.Type: GrantFiled: November 4, 2022Date of Patent: March 19, 2024Assignee: Intel CorporationInventors: Shaopeng He, Cunming Liang, Jiang Yu, Ziye Yang, Ping Yu, Bo Cui, Jingjing Wu, Liang Ma, Hongjun Ni, Zhiguo Wen, Changpeng Liu, Anjali Singhai Jain, Daniel Daly, Yadong Li
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Publication number: 20230417751Abstract: Provided herein is a method and system for detecting kinase activity, comprising: providing one or more mutated kinases, wherein the one or more mutated kinases comprise a mutation that enlarges an ATP binding pocket of the kinase; contacting the one or more mutated kinases with an ATP or ADP analog-nanoparticle conjugate capable of intracellular delivery of the ATP or ADP analog-nanoparticle conjugate, wherein the ATP or ADP analog comprises a detectable label; assaying the one or more mutated kinases under conditions in which the ATP or ADP analog-nanoparticle conjugate contacts the one or more mutated kinases, wherein the one or more kinases react to transfer the detectable label to the substrate, wherein the ATP analog only fluoresces upon contact with the ATP binding pocket of the kinase.Type: ApplicationFiled: May 24, 2023Publication date: December 28, 2023Inventors: Degeng Wang, Leaf Huang, Hongjun Liang, Weimin Gao
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Publication number: 20220364143Abstract: The present invention includes method and system for detecting kinase activity in vivo, comprising: providing a cell that comprises one or more mutated kinases, wherein the one or more mutated kinases comprise a mutation that enlarges an ATP binding pocket of the kinase; contacting the cell with an ATP analog-nanoparticle conjugate capable of intracellular delivery of the ATP analog-nanoparticle conjugate, wherein the ATP analog comprises a detectable label; culturing the cells under conditions in which the ATP analog-nanoparticle conjugate contacts the one or more mutated kinases in cellulo, wherein the detectable label is transferred from the ATP analog-nanoparticle conjugate to a substrate of the one or more mutated kinases, wherein the one or more kinases react to transfer the detectable label to the substrate.Type: ApplicationFiled: May 11, 2022Publication date: November 17, 2022Inventors: Degeng Wang, Leaf Huang, Hongjun Liang, Fengqian Chen, Weimin Gao
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Patent number: 11471411Abstract: The present invention includes compositions, methods, and methods of making and using a nanoscale discoidal membrane comprising: an amphiphilic membrane patch comprising self-assembled molecular amphiphiles capable of supporting one or more membrane proteins in the amphiphilic membrane patch; and one or more amphipathic scaffold macromolecules that encase the nanoscale discoidal membrane.Type: GrantFiled: September 18, 2018Date of Patent: October 18, 2022Assignee: Texas Tech University SystemInventors: Guillermo A. Altenberg, Hongjun Liang
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Patent number: 11395804Abstract: The present invention includes compositions and methods of making hydrophilic nanostructured antibiotics (i.e. nanoantibiotics), including nanoantibiotics that use environmentally degradable biomolecules as the backbone building blocks, wherein the backbone building blocks can include spherical backbones such as sucroses, cyclodextrins, glycogens, and phytoglycogen with different diameters, or rod-like backbone building blocks such as dextrins, amyloses, and celluloses with different lengths. These hydrophilic nanoantibiotics with well-defined sizes and shapes can selectively disrupt bacterial membranes (i.e., serve as membrane-active antimicrobials) while being benign to mammalian cells. Depending on the size and shape difference of the hydrophilic nanoantibiotics, they can also selectively kill one type of bacteria (e.g., gram-negative) over another type (e.g., gram-positive).Type: GrantFiled: February 1, 2019Date of Patent: July 26, 2022Assignee: Texas Tech University SystemInventor: Hongjun Liang
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Patent number: 11332555Abstract: The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.Type: GrantFiled: October 7, 2020Date of Patent: May 17, 2022Assignee: Texas Tech University SystemInventors: Guillermo A. Altenberg, Hongjun Liang
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Publication number: 20210253453Abstract: The disclosure claims a magnetizing device and method for preparing magnetized water for dust fall of an underground coal mine. The device is formed by a plurality of magnetic drums in a parallel connection with connecting elbows in a āUā-shaped arrangement manner. Each magnetic drum consists of an external magnet, an internal magnet, a hollow pressure pipe, a spiral blade, a screen magnet cover, a connecting steel column, a pressure pipe, a closed nut and a flange plate. According to the disclosure, the internal and external magnets are arranged on a spiral flow channel consisting of the hollow pressure pipe, the spiral blade and the pressure blade by means of an alternating arrangement, thereby building an efficient magnetization environment combined by pulse cutting magnetization and spiral turbulence, enabling that the water for dust fall flowing through is magnetized continuously and efficiently.Type: ApplicationFiled: August 19, 2017Publication date: August 19, 2021Inventors: Botao QIN, Qun ZHOU, Jun WANG, Hongjun LIANG, Anliang WANG, Ang GAO, Yuan GAO, Jin HOU
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Publication number: 20210171673Abstract: The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.Type: ApplicationFiled: October 7, 2020Publication date: June 10, 2021Inventors: Guillermo A. Altenberg, Hongjun Liang
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Patent number: 10829571Abstract: The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.Type: GrantFiled: August 30, 2018Date of Patent: November 10, 2020Assignee: Texas Tech University SystemInventors: Guillermo A. Altenberg, Hongjun Liang
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Publication number: 20200281855Abstract: The present invention includes compositions, methods, and methods of making and using a nanoscale discoidal membrane comprising: an amphiphilic membrane patch comprising self-assembled molecular amphiphiles capable of supporting one or more membrane proteins in the amphiphilic membrane patch; and one or more amphipathic scaffold macromolecules that encase the nanoscale discoidal membrane.Type: ApplicationFiled: September 18, 2018Publication date: September 10, 2020Inventors: Guillermo A. Altenberg, Hongjun Liang
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Publication number: 20190231703Abstract: The present invention includes compositions and methods of making hydrophilic nanostructured antibiotics (i.e. nanoantibiotics), including nanoantibiotics that use environmentally degradable biomolecules as the backbone building blocks, wherein the backbone building blocks can include spherical backbones such as sucroses, cyclodextrins, glycogens, and phytoglycogen with different diameters, or rod-like backbone building blocks such as dextrins, amyloses, and celluloses with different lengths. These hydrophilic nanoantibiotics with well-defined sizes and shapes can selectively disrupt bacterial membranes (i.e., serve as membrane-active antimicrobials) while being benign to mammalian cells. Depending on the size and shape difference of the hydrophilic nanoantibiotics, they can also selectively kill one type of bacteria (e.g., gram-negative) over another type (e.g., gram-positive).Type: ApplicationFiled: February 1, 2019Publication date: August 1, 2019Inventor: Hongjun Liang
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Publication number: 20190062469Abstract: The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.Type: ApplicationFiled: August 30, 2018Publication date: February 28, 2019Inventors: Guillermo A. Altenberg, Hongjun Liang
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Patent number: 9464268Abstract: A reusable composite paramagnetic particle may comprise a paramagnetic core encased by a protective material to which is grafted a tendril layer comprising a plurality of polymeric chains. The polymeric chains may be designed to interact with a microorganism. The interaction between the microorganism and the polymeric chain may be electrostatic. The nanoparticle may be used in a method to isolate or recover microorganisms from solutions using an externally applied magnetic field.Type: GrantFiled: December 1, 2014Date of Patent: October 11, 2016Assignee: COLORADO SCHOOL OF MINESInventor: Hongjun Liang
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Publication number: 20150152376Abstract: A reusable composite paramagnetic particle may comprise a paramagnetic core encased by a protective material to which is grafted a tendril layer comprising a plurality of polymeric chains. The polymeric chains may be designed to interact with a microorganism. The interaction between the microorganism and the polymeric chain may be electrostatic. The nanoparticle may be used in a method to isolate or recover microorganisms from solutions using an externally applied magnetic field.Type: ApplicationFiled: December 1, 2014Publication date: June 4, 2015Inventor: Hongjun Liang
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Publication number: 20140141089Abstract: The disclosure is directed to a nanoparticle comprising a porous framework core including a porous framework material and a compound, and a lipid layer disposed on the surface of the porous framework core.Type: ApplicationFiled: February 11, 2010Publication date: May 22, 2014Applicant: Colorado School of MinesInventor: Hongjun Liang
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Publication number: 20120037840Abstract: Methods and compositions for removing a contaminant from its environment. The method includes forming a magnetic composition comprising the contaminant and an amphiphilic substance, and applying a magnetic field to the magnetic composition so as to separate the magnetic composition from the environment. One composition includes a micelle array confined in a magnetic mesoporous framework. Another composition is formed by adhering an amphiphilic material comprising functional surface groups to a contaminant, then interacting a magnetic material with the functional surface groups of the amphiphilic material. In various versions, the contaminant can be a hydrophobic organic compound, or a fullerene-related nanoparticle. The methods can also be used to purify hydrophobic organic compounds or fullerene-related nanoparticles.Type: ApplicationFiled: February 25, 2009Publication date: February 16, 2012Inventors: Galen Stucky, Arturo A. Keller, Yifeng Shi, Peng Wang, Qihui Shi, Hongjun Liang
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Publication number: 20110201076Abstract: A reusable composite paramagnetic particle may comprise a paramagnetic core encased by a protective material to which is grafted a tendril layer comprising a plurality of polymeric chains. The polymeric chains may be designed to interact with a microorganism. The interaction between the microorganism and the polymeric chain may be electrostatic. The nanoparticle may be used in a method to isolate or recover microorganisms from solutions using an externally applied magnetic field.Type: ApplicationFiled: January 21, 2011Publication date: August 18, 2011Applicant: COLORADO SCHOOL OF MINESInventor: Hongjun Liang