Patents by Inventor Hongjun Zhang

Hongjun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12275729
    Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: April 15, 2025
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Yongqi Deng, Abdelghani Achab, David Jonathan Bennett, Indu Bharathan, Xavier Fradera, Craig Gibeau, Yongxin Han, Derun Li, Kun Liu, Qinglin Pu, Sulagna Sanyal, David Sloman, Wensheng Yu, Hongjun Zhang
  • Patent number: 12257737
    Abstract: Provided are an ecological slope anti-corrosion timber pile and a treatment device and method therefor, belonging to the field of ecological engineering. The device includes a gasification furnace, and first, second and third carbonization chambers, each internally provided with a main gas pipeline, and multiple rows of radially distributed branch gas pipes are vertically disposed thereon and provided with electronic igniters. Multiple rows of radially distributed timber piles are vertically inside the carbonization chambers and between the branch gas pipes. The gasification furnace is connected to the main gas pipeline of the first carbonization chamber through a gas booster pump. The first carbonization chamber is connected to an air blower, the first and second carbonization chambers are connected through a joint pipe, the second and third carbonization chambers are connected through a pipeline, and the third carbonization chamber is connected to the gasification furnace through a gas delivery pipe.
    Type: Grant
    Filed: October 1, 2024
    Date of Patent: March 25, 2025
    Assignee: Harbin Normal University
    Inventors: Hanxi Wang, Shuying Zang, Hongjun Zhang
  • Patent number: 12240867
    Abstract: Described herein are compounds of Formula (I), or a pharmaceutically acceptable salt thereof. The compounds of Formula (I) act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: March 4, 2025
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Abdelghani Abe Achab, Matthew L. Childers, Jared N. Cumming, Symon Gathiaka, Charles A. Lesburg, Derun Li, Min Lu, Matthew J. Mitcheltree, Anandan Palani, Rachel L. Palte, Hongjun Zhang
  • Publication number: 20250067424
    Abstract: The present invention patent relates to the technical field of children's toys, in particular to a tap light. The tap light includes a lamp holder and a lampshade. A side of the lampshade is provided with a first opening that communicates with its internal space. The lamp holder is clamped at the first opening of the lampshade. An annular clamping groove is defined between base bodies for clamping the connection part. Since the annular clamping groove clamps the connection part, the two will form a seal, effectively preventing water from the external environment from entering the tap light through the gap between the lamp holder and the lampshade. Even if the child puts the tap light into the bathtub or basin while playing, or directly rinses the tap light at the sink, it will not cause the tap light to fail due to water ingress.
    Type: Application
    Filed: September 3, 2024
    Publication date: February 27, 2025
    Inventor: Hongjun Zhang
  • Patent number: 12215116
    Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 4, 2025
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Abdelghani Abe Achab, Matthew L. Childers, Jared N. Cumming, Christian Fischer, Symon Gathiaka, Hakan Gunaydin, Charles A. Lesburg, Derun Li, Min Lu, Anandan Palani, Rachel L. Palte, Qinglin Pu, David L. Sloman, Sung-Sau So, Chunrui Sun, Hongjun Zhang
  • Patent number: 12213818
    Abstract: The present disclosure may provide a radiation system including a first rotation portion, a second rotation portion, a treatment head, one or more imaging sources, and at least one detector. At least a portion of the treatment head may be disposed in the first rotation portion. At least one of the one or more imaging sources may be disposed in the second rotation portion. The second rotation portion may be able to rotate independently from the first rotation portion.
    Type: Grant
    Filed: March 8, 2023
    Date of Patent: February 4, 2025
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Buliang Sun, Cheng Ni, Wei Zhang, Li Wang, Hongjun Zhang, Jian Zhang, Tao Liu, Can Liao
  • Publication number: 20250018596
    Abstract: Provided are an ecological slope anti-corrosion timber pile and a treatment device and method therefor, belonging to the field of ecological engineering. The device includes a gasification furnace, and first, second and third carbonization chambers, each internally provided with a main gas pipeline, and multiple rows of radially distributed branch gas pipes are vertically disposed thereon and provided with electronic igniters. Multiple rows of radially distributed timber piles are vertically inside the carbonization chambers and between the branch gas pipes. The gasification furnace is connected to the main gas pipeline of the first carbonization chamber through a gas booster pump. The first carbonization chamber is connected to an air blower, the first and second carbonization chambers are connected through a joint pipe, the second and third carbonization chambers are connected through a pipeline, and the third carbonization chamber is connected to the gasification furnace through a gas delivery pipe.
    Type: Application
    Filed: October 1, 2024
    Publication date: January 16, 2025
    Inventors: Hanxi WANG, Shuying ZANG, Hongjun ZHANG
  • Patent number: 12186118
    Abstract: A system and method relating to a radiation based imaging are provided. The system may include a radiation source, a detector, a first grid, and a second grid. The detector may include a plurality of detector cells. The first grid may be located between the radiation source and the detector and include a plurality of first radiation transmitting sections. The second grid may be located between the first grid and the detector and include a plurality of second radiation transmitting sections. An extending direction of at least one of the plurality of first radiation transmitting sections may be different from that of at least one of the plurality of second radiation transmitting sections.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: January 7, 2025
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventor: Hongjun Zhang
  • Publication number: 20240425524
    Abstract: Described herein are compounds of Formula I; and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, m, n, and p are as defined herein. The compounds of Formula I, and pharmaceutically acceptable salts thereof, act as RIPK1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for RIPK1-related diseases.
    Type: Application
    Filed: October 24, 2022
    Publication date: December 26, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Abdelghani Abe Achab, Jenny Lorena Rico Duque, Xavier Fradera, Joey L. Methot, Phieng Siliphaivanh, Brandon A. Vara, Hongjun Zhang
  • Patent number: 12157727
    Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: December 3, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Yongxin Han, Yongqi Deng, Hua Zhou, Meredeth A. McGowan, Hongjun Zhang, Wensheng Yu, Brett A. Hopkins, Xavier Fradera, Nunzio Sciammetta
  • Patent number: 12117150
    Abstract: The present invention patent relates to the technical field of children's toys, in particular to a tap light. The tap light includes a lamp holder and a lampshade. A side of the lampshade is provided with a first opening that communicates with its internal space. The lamp holder is clamped at the first opening of the lampshade. An annular clamping groove is defined between base bodies for clamping the connection part. Since the annular clamping groove clamps the connection part, the two will form a seal, effectively preventing water from the external environment from entering the tap light through the gap between the lamp holder and the lampshade. Even if the child puts the tap light into the bathtub or basin while playing, or directly rinses the tap light at the sink, it will not cause the tap light to fail due to water ingress.
    Type: Grant
    Filed: December 29, 2023
    Date of Patent: October 15, 2024
    Assignee: Shenzhen Huamingjun Rubber Co., Ltd
    Inventor: Hongjun Zhang
  • Patent number: 12091676
    Abstract: Provided for the first time in the present invention is a method for preparing a non-human primate somatic cell cloned animal, which method specifically comprises the steps of: (i) providing a reconstructed egg, wherein the egg comes from the non-human primate (ii) activating the reconstructed egg to form an activated reconstructed egg or activated reconstructed embryo formed by the reconstructed egg; (iii) reprogramming (a) the activated reconstructed egg or (b) embryonic cells of the activated reconstructed embryo to obtain a reprogrammed reconstructed egg or reprogrammed reconstructed embryo; and (iv) regenerating the reprogrammed reconstructed egg or reprogrammed reconstructed embryo to obtain the non-human primate somatic cell cloned animal. The method of the present invention can significantly improve the developmental capacity of nucleus-transplanted embryos in non-human primates (such as monkeys).
    Type: Grant
    Filed: December 25, 2018
    Date of Patent: September 17, 2024
    Assignee: CENTER FOR EXCELLENCE IN BRAIN SCIENCE AND INTELLIGENCE TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Qiang Sun, Zhen Liu, Hongjun Zhang, Yijun Cai, Zhaodi Liao, Yuting Xu, Yan Wang, Yanhong Nie
  • Patent number: 12065438
    Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Formula (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: August 20, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Yongxin Han, David Jonathan Bennett, Indu Bharathan, Liangqin Guo, Brett A. Hopkins, Xianhai Huang, Derun Li, Min Lu, Alexander Pasternak, David L. Sloman, Hongjun Zhang, Hua Zhou
  • Patent number: 12035751
    Abstract: Disclosed are an atomizing head, an atomizer, and an electronic cigarette. The atomizing head includes a contacting member, an atomizing core and a core seat, wherein an atomizing cavity is formed in the core seat, the atomizing core is connected to the core seat, the atomizing core is a porous ceramic body, the atomizing core is provided with a conductive member, and the contacting member is in contact with the conductive member so as to realize an electrical connection between the contacting member and the atomizing core. The atomizing head, the atomizer and the electronic cigarette are easily assembled, thereby improving the assembly efficiency and reducing the production cost.
    Type: Grant
    Filed: June 14, 2021
    Date of Patent: July 16, 2024
    Assignee: CHANGZHOU PATENT ELECTRONIC TECHNOLOGY CO., LTD
    Inventors: Weihua Qiu, Hongjun Zhang
  • Patent number: 11992489
    Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: May 28, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Dane Clausen, Xavier Fradera, Yongxin Han, Alexander Pasternak, Li Xiao, Hongjun Zhang
  • Publication number: 20230329664
    Abstract: The present disclosure relates to a slip ring assembly. The slip ring assembly may include a first slip ring, a second slip ring, and a transmission component. The transmission component may be configured to facilitate at least one of: data transmission of the first slip ring, data transmission of the second slip ring, power transmission of the first slip ring, or power transmission of the second slip ring.
    Type: Application
    Filed: June 12, 2023
    Publication date: October 19, 2023
    Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Hongtao WANG, Tao LIU, Cheng NI, Li WANG, Hongjun ZHANG, Wei ZHANG, Tuota XING, Buliang SUN, Yansi YANG, Hualing WANG, Shaomin XIAO
  • Patent number: 11708616
    Abstract: The present disclosure provides methods and materials for determining if antibiotic resistant H. pylori is present in a sample. The methods may comprise obtaining a threshold level of H. pylori DNA from the sample, amplifying a region of the H. pylori DNA to generate multiple copies of the region of the H. pylori DNA, sequencing the multiple copies of the region of the H. pylori DNA, comparing sequences of multiple copies of the region of the H. pylori DNA to a reference sequence, identifying the presence of a mutation in multiple copies of the region of the H. pylori DNA, and determining a number of the multiple copies of the region of the H. pylori DNA with the mutation, wherein antibiotic resistant H. pylori is present in the sample when the number of the multiple copies of the region of the H. pylori DNA with the mutation is above a predetermined amount.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: July 25, 2023
    Assignee: AMERICAN MOLECULAR LABORATORIES INC.
    Inventors: Hongjun Zhang, Yi Zhou, Rajarao Kakuturu
  • Patent number: D1034830
    Type: Grant
    Filed: April 12, 2023
    Date of Patent: July 9, 2024
    Assignee: SHENZHEN HUAMINGJUN RUBBER CO., LTD
    Inventor: Hongjun Zhang
  • Patent number: D1066989
    Type: Grant
    Filed: May 3, 2023
    Date of Patent: March 18, 2025
    Assignee: SHENZHEN HUAMINGJUN RUBBER CO., LTD
    Inventor: Hongjun Zhang
  • Patent number: D1069153
    Type: Grant
    Filed: November 16, 2022
    Date of Patent: April 1, 2025
    Assignee: AMERICAN MOLECULAR LABORATORIES INC.
    Inventor: Hongjun Zhang