Patents by Inventor Hongjun Zhang
Hongjun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12275729Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: October 29, 2018Date of Patent: April 15, 2025Assignee: Merck Sharp & Dohme LLCInventors: Yongqi Deng, Abdelghani Achab, David Jonathan Bennett, Indu Bharathan, Xavier Fradera, Craig Gibeau, Yongxin Han, Derun Li, Kun Liu, Qinglin Pu, Sulagna Sanyal, David Sloman, Wensheng Yu, Hongjun Zhang
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Patent number: 12257737Abstract: Provided are an ecological slope anti-corrosion timber pile and a treatment device and method therefor, belonging to the field of ecological engineering. The device includes a gasification furnace, and first, second and third carbonization chambers, each internally provided with a main gas pipeline, and multiple rows of radially distributed branch gas pipes are vertically disposed thereon and provided with electronic igniters. Multiple rows of radially distributed timber piles are vertically inside the carbonization chambers and between the branch gas pipes. The gasification furnace is connected to the main gas pipeline of the first carbonization chamber through a gas booster pump. The first carbonization chamber is connected to an air blower, the first and second carbonization chambers are connected through a joint pipe, the second and third carbonization chambers are connected through a pipeline, and the third carbonization chamber is connected to the gasification furnace through a gas delivery pipe.Type: GrantFiled: October 1, 2024Date of Patent: March 25, 2025Assignee: Harbin Normal UniversityInventors: Hanxi Wang, Shuying Zang, Hongjun Zhang
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Patent number: 12240867Abstract: Described herein are compounds of Formula (I), or a pharmaceutically acceptable salt thereof. The compounds of Formula (I) act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.Type: GrantFiled: December 13, 2019Date of Patent: March 4, 2025Assignee: Merck Sharp & Dohme LLCInventors: Abdelghani Abe Achab, Matthew L. Childers, Jared N. Cumming, Symon Gathiaka, Charles A. Lesburg, Derun Li, Min Lu, Matthew J. Mitcheltree, Anandan Palani, Rachel L. Palte, Hongjun Zhang
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Publication number: 20250067424Abstract: The present invention patent relates to the technical field of children's toys, in particular to a tap light. The tap light includes a lamp holder and a lampshade. A side of the lampshade is provided with a first opening that communicates with its internal space. The lamp holder is clamped at the first opening of the lampshade. An annular clamping groove is defined between base bodies for clamping the connection part. Since the annular clamping groove clamps the connection part, the two will form a seal, effectively preventing water from the external environment from entering the tap light through the gap between the lamp holder and the lampshade. Even if the child puts the tap light into the bathtub or basin while playing, or directly rinses the tap light at the sink, it will not cause the tap light to fail due to water ingress.Type: ApplicationFiled: September 3, 2024Publication date: February 27, 2025Inventor: Hongjun Zhang
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Patent number: 12215116Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.Type: GrantFiled: March 8, 2019Date of Patent: February 4, 2025Assignee: Merck Sharp & Dohme LLCInventors: Abdelghani Abe Achab, Matthew L. Childers, Jared N. Cumming, Christian Fischer, Symon Gathiaka, Hakan Gunaydin, Charles A. Lesburg, Derun Li, Min Lu, Anandan Palani, Rachel L. Palte, Qinglin Pu, David L. Sloman, Sung-Sau So, Chunrui Sun, Hongjun Zhang
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Patent number: 12213818Abstract: The present disclosure may provide a radiation system including a first rotation portion, a second rotation portion, a treatment head, one or more imaging sources, and at least one detector. At least a portion of the treatment head may be disposed in the first rotation portion. At least one of the one or more imaging sources may be disposed in the second rotation portion. The second rotation portion may be able to rotate independently from the first rotation portion.Type: GrantFiled: March 8, 2023Date of Patent: February 4, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Buliang Sun, Cheng Ni, Wei Zhang, Li Wang, Hongjun Zhang, Jian Zhang, Tao Liu, Can Liao
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Publication number: 20250018596Abstract: Provided are an ecological slope anti-corrosion timber pile and a treatment device and method therefor, belonging to the field of ecological engineering. The device includes a gasification furnace, and first, second and third carbonization chambers, each internally provided with a main gas pipeline, and multiple rows of radially distributed branch gas pipes are vertically disposed thereon and provided with electronic igniters. Multiple rows of radially distributed timber piles are vertically inside the carbonization chambers and between the branch gas pipes. The gasification furnace is connected to the main gas pipeline of the first carbonization chamber through a gas booster pump. The first carbonization chamber is connected to an air blower, the first and second carbonization chambers are connected through a joint pipe, the second and third carbonization chambers are connected through a pipeline, and the third carbonization chamber is connected to the gasification furnace through a gas delivery pipe.Type: ApplicationFiled: October 1, 2024Publication date: January 16, 2025Inventors: Hanxi WANG, Shuying ZANG, Hongjun ZHANG
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Patent number: 12186118Abstract: A system and method relating to a radiation based imaging are provided. The system may include a radiation source, a detector, a first grid, and a second grid. The detector may include a plurality of detector cells. The first grid may be located between the radiation source and the detector and include a plurality of first radiation transmitting sections. The second grid may be located between the first grid and the detector and include a plurality of second radiation transmitting sections. An extending direction of at least one of the plurality of first radiation transmitting sections may be different from that of at least one of the plurality of second radiation transmitting sections.Type: GrantFiled: February 28, 2022Date of Patent: January 7, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Hongjun Zhang
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Publication number: 20240425524Abstract: Described herein are compounds of Formula I; and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, m, n, and p are as defined herein. The compounds of Formula I, and pharmaceutically acceptable salts thereof, act as RIPK1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for RIPK1-related diseases.Type: ApplicationFiled: October 24, 2022Publication date: December 26, 2024Applicant: Merck Sharp & Dohme LLCInventors: Abdelghani Abe Achab, Jenny Lorena Rico Duque, Xavier Fradera, Joey L. Methot, Phieng Siliphaivanh, Brandon A. Vara, Hongjun Zhang
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Patent number: 12157727Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: June 8, 2020Date of Patent: December 3, 2024Assignee: Merck Sharp & Dohme LLCInventors: Yongxin Han, Yongqi Deng, Hua Zhou, Meredeth A. McGowan, Hongjun Zhang, Wensheng Yu, Brett A. Hopkins, Xavier Fradera, Nunzio Sciammetta
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Patent number: 12117150Abstract: The present invention patent relates to the technical field of children's toys, in particular to a tap light. The tap light includes a lamp holder and a lampshade. A side of the lampshade is provided with a first opening that communicates with its internal space. The lamp holder is clamped at the first opening of the lampshade. An annular clamping groove is defined between base bodies for clamping the connection part. Since the annular clamping groove clamps the connection part, the two will form a seal, effectively preventing water from the external environment from entering the tap light through the gap between the lamp holder and the lampshade. Even if the child puts the tap light into the bathtub or basin while playing, or directly rinses the tap light at the sink, it will not cause the tap light to fail due to water ingress.Type: GrantFiled: December 29, 2023Date of Patent: October 15, 2024Assignee: Shenzhen Huamingjun Rubber Co., LtdInventor: Hongjun Zhang
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Patent number: 12091676Abstract: Provided for the first time in the present invention is a method for preparing a non-human primate somatic cell cloned animal, which method specifically comprises the steps of: (i) providing a reconstructed egg, wherein the egg comes from the non-human primate (ii) activating the reconstructed egg to form an activated reconstructed egg or activated reconstructed embryo formed by the reconstructed egg; (iii) reprogramming (a) the activated reconstructed egg or (b) embryonic cells of the activated reconstructed embryo to obtain a reprogrammed reconstructed egg or reprogrammed reconstructed embryo; and (iv) regenerating the reprogrammed reconstructed egg or reprogrammed reconstructed embryo to obtain the non-human primate somatic cell cloned animal. The method of the present invention can significantly improve the developmental capacity of nucleus-transplanted embryos in non-human primates (such as monkeys).Type: GrantFiled: December 25, 2018Date of Patent: September 17, 2024Assignee: CENTER FOR EXCELLENCE IN BRAIN SCIENCE AND INTELLIGENCE TECHNOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Qiang Sun, Zhen Liu, Hongjun Zhang, Yijun Cai, Zhaodi Liao, Yuting Xu, Yan Wang, Yanhong Nie
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Patent number: 12065438Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Formula (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: November 1, 2019Date of Patent: August 20, 2024Assignee: Merck Sharp & Dohme LLCInventors: Yongxin Han, David Jonathan Bennett, Indu Bharathan, Liangqin Guo, Brett A. Hopkins, Xianhai Huang, Derun Li, Min Lu, Alexander Pasternak, David L. Sloman, Hongjun Zhang, Hua Zhou
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Patent number: 12035751Abstract: Disclosed are an atomizing head, an atomizer, and an electronic cigarette. The atomizing head includes a contacting member, an atomizing core and a core seat, wherein an atomizing cavity is formed in the core seat, the atomizing core is connected to the core seat, the atomizing core is a porous ceramic body, the atomizing core is provided with a conductive member, and the contacting member is in contact with the conductive member so as to realize an electrical connection between the contacting member and the atomizing core. The atomizing head, the atomizer and the electronic cigarette are easily assembled, thereby improving the assembly efficiency and reducing the production cost.Type: GrantFiled: June 14, 2021Date of Patent: July 16, 2024Assignee: CHANGZHOU PATENT ELECTRONIC TECHNOLOGY CO., LTDInventors: Weihua Qiu, Hongjun Zhang
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Patent number: 11992489Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: August 12, 2019Date of Patent: May 28, 2024Assignee: Merck Sharp & Dohme LLCInventors: Dane Clausen, Xavier Fradera, Yongxin Han, Alexander Pasternak, Li Xiao, Hongjun Zhang
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Publication number: 20230329664Abstract: The present disclosure relates to a slip ring assembly. The slip ring assembly may include a first slip ring, a second slip ring, and a transmission component. The transmission component may be configured to facilitate at least one of: data transmission of the first slip ring, data transmission of the second slip ring, power transmission of the first slip ring, or power transmission of the second slip ring.Type: ApplicationFiled: June 12, 2023Publication date: October 19, 2023Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Hongtao WANG, Tao LIU, Cheng NI, Li WANG, Hongjun ZHANG, Wei ZHANG, Tuota XING, Buliang SUN, Yansi YANG, Hualing WANG, Shaomin XIAO
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Patent number: 11708616Abstract: The present disclosure provides methods and materials for determining if antibiotic resistant H. pylori is present in a sample. The methods may comprise obtaining a threshold level of H. pylori DNA from the sample, amplifying a region of the H. pylori DNA to generate multiple copies of the region of the H. pylori DNA, sequencing the multiple copies of the region of the H. pylori DNA, comparing sequences of multiple copies of the region of the H. pylori DNA to a reference sequence, identifying the presence of a mutation in multiple copies of the region of the H. pylori DNA, and determining a number of the multiple copies of the region of the H. pylori DNA with the mutation, wherein antibiotic resistant H. pylori is present in the sample when the number of the multiple copies of the region of the H. pylori DNA with the mutation is above a predetermined amount.Type: GrantFiled: November 16, 2018Date of Patent: July 25, 2023Assignee: AMERICAN MOLECULAR LABORATORIES INC.Inventors: Hongjun Zhang, Yi Zhou, Rajarao Kakuturu
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Patent number: D1034830Type: GrantFiled: April 12, 2023Date of Patent: July 9, 2024Assignee: SHENZHEN HUAMINGJUN RUBBER CO., LTDInventor: Hongjun Zhang
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Patent number: D1066989Type: GrantFiled: May 3, 2023Date of Patent: March 18, 2025Assignee: SHENZHEN HUAMINGJUN RUBBER CO., LTDInventor: Hongjun Zhang
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Patent number: D1069153Type: GrantFiled: November 16, 2022Date of Patent: April 1, 2025Assignee: AMERICAN MOLECULAR LABORATORIES INC.Inventor: Hongjun Zhang