Patents by Inventor Hongkui WANG

Hongkui WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11110202
    Abstract: A differential tissue-engineered nerve including motor-like nerves and sensory-like nerves. The motor-like nerve and the sensory-like nerve respectively includes a motor-like nerve outer tube and a motor-like nerve fiber in the outer tube as well as a sensory-like nerve outer tube and a sensory-like nerve fiber in the outer tube. Schwann cells and/or fibroblasts derived from motor nerves and sensory nerves are respectively contained in surfaces or pores of the motor-like and sensory-like nerve outer tubes. Transsynaptic signal molecules Neuroligin-1 and Neuroligin-2 are contained in surfaces or pores of the motor-like and sensory-like nerve fibers. Neuroligin-1 is selectively used to specifically promote synaptic remodeling of motor neurons, while Neuroligin-2 is selectively used to specifically promote synaptic remodeling of sensory neurons, so that repair efficiency of motor nerve cells and sensory nerve cells is improved.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: September 7, 2021
    Assignee: NANTONG UNIVERSITY
    Inventors: Xin Tang, Cheng Sun, Gang Chen, Xiaosong Gu, Yumin Yang, Fei Ding, Yanpei Gong, Qianru He, Hongkui Wang, Mi Shen
  • Publication number: 20210268149
    Abstract: A differential tissue-engineered nerve including motor-like nerves and sensory-like nerves. The motor-like nerve and the sensory-like nerve respectively includes a motor-like nerve outer tube and a motor-like nerve fiber in the outer tube as well as a sensory-like nerve outer tube and a sensory-like nerve fiber in the outer tube. Schwann cells and/or fibroblasts derived from motor nerves and sensory nerves are respectively contained in surfaces or pores of the motor-like and sensory-like nerve outer tubes. Transsynaptic signal molecules Neuroligin-1 and Neuroligin-2 are contained in surfaces or pores of the motor-like and sensory-like nerve fibers. Neuroligin-1 is selectively used to specifically promote synaptic remodeling of motor neurons, while Neuroligin-2 is selectively used to specifically promote synaptic remodeling of sensory neurons, so that repair efficiency of motor nerve cells and sensory nerve cells is improved.
    Type: Application
    Filed: September 11, 2019
    Publication date: September 2, 2021
    Inventors: Xin TANG, Cheng SUN, Gang CHEN, Xiaosong GU, Yumin YANG, Fei DING, Yanpei GONG, Qianru HE, Hongkui WANG, Mi SHEN
  • Patent number: 10736695
    Abstract: The present invention provides a visual fractional laser instrument, which comprises: an positioning cannula, the positioning cannula being a hollow tube with openings at both ends so as to locate a lesion site and define a path of the laser; a beam combiner component, the beam combiner component being a hollow tube with openings at both ends, and a side opening is provided on a side of the beam combiner component, wherein one end of the beam combiner component is connected to one end of the positioning cannula; a camera connected to the beam combiner component by the side opening to image the lesion site; a laser scanning component connected to another end of the beam combiner component for generating a laser beam used to scan the lesion site according to the image of the lesion site; and a control system connected to the laser scanning component and the camera, respectively.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: August 11, 2020
    Assignee: ZWXG (BEIJING) TECHNOLOGY CO., LTD
    Inventors: Kefei Zhang, Hongwei Wang, Yu Zhang, Shenghua Zheng, Ning Bao, Hongkui Wang, Hong Zheng, Yuguan Zhang, Rong Zheng, Jian Zhao, Heyi Zhang
  • Publication number: 20180092694
    Abstract: The present invention provides a visual fractional laser instrument, which comprises: an positioning cannula, the positioning cannula being a hollow tube with openings at both ends so as to locate a lesion site and define a path of the laser; a beam combiner component, the beam combiner component being a hollow tube with openings at both ends, and a side opening is provided on a side of the beam combiner component, wherein one end of the beam combiner component is connected to one end of the positioning cannula; a camera connected to the beam combiner component by the side opening to image the lesion site; a laser scanning component connected to another end of the beam combiner component for generating a laser beam used to scan the lesion site according to the image of the lesion site; and a control system connected to the laser scanning component and the camera, respectively.
    Type: Application
    Filed: March 1, 2016
    Publication date: April 5, 2018
    Inventors: Kefei ZHANG, Hongwei WANG, Yu ZHANG, Shenghua ZHENG, Ning BAO, Hongkui WANG, Hong ZHENG, Yuguan ZHANG, Rong ZHENG, Jian ZHAO, Heyi ZHANG
  • Patent number: 9918786
    Abstract: Devices, components, apparatus, and/or methods for using and making a combination spinal disk herniation repositioning and radiofrequency apparatus (RFA) or device that uses one or more repositioning probes and one or more needles/electrodes, wherein the device's probe repositions, and the electrode or needle treats or ablates, an injured, torn, herniated, or displaced vertebral disc propulus and/or nucleus, and wherein one or more side probes or needles are used to reposition or treat the spinal disk herniation, optionally followed by medicine/ozone therapy of the disc being treated.
    Type: Grant
    Filed: October 6, 2013
    Date of Patent: March 20, 2018
    Inventors: Hongkui Wang, Jinsheng Wang
  • Publication number: 20150100052
    Abstract: Devices, components, apparatus, and/or methods for using and making a combination spinal disk herniation repositioning and radiofrequency apparatus (RFA) or device that uses one or more repositioning probes and one or more needles/electrodes, wherein the device's probe repositions, and the electrode or needle treats or ablates, an injured, torn, herniated, or displaced vertebral disc propulus and/or nucleus, and wherein one or more side probes or needles are used to reposition or treat the spinal disk herniation, optionally followed by medicine/ozone therapy of the disc being treated.
    Type: Application
    Filed: October 6, 2013
    Publication date: April 9, 2015
    Inventors: Jinsheng WANG, Hongkui WANG