Abstract: The present invention relates to a polyvinyl alcohol/sodium alginate/hydroxyapatite composite fibrous membrane, and a preparation method and an application thereof. The preparation method of the composite fibrous membrane includes the following steps: firstly, reacting a diammonium hydrogen phosphate with a calcium nitrate to prepare a hydroxyapatite, and performing ultrasonic dispersion on the hydroxyapatite with a sodium alginate to form a stable hydroxyapatite suspension; separately preparing a sodium alginate solution of which the mass fraction is 2% and a polyvinyl alcohol solution of which the mass fraction is 18% using the above stable hydroxyapatite suspension; and finally, proportionally and uniformly mixing the two solutions, and performing electrospinning.

Abstract: The present invention relates to a polyvinyl alcohol/sodium alginate/hydroxyapatite composite fibrous membrane, and a preparation method and an application thereof. The preparation method of the composite fibrous membrane includes the following steps: firstly, reacting a diammonium hydrogen phosphate with a calcium nitrate to prepare a hydroxyapatite, and performing ultrasonic dispersion on the hydroxyapatite with a sodium alginate to form a stable hydroxyapatite suspension; separately preparing a sodium alginate solution of which the mass fraction is 2% and a polyvinyl alcohol solution of which the mass fraction is 18% using the above stable hydroxyapatite suspension; and finally, proportionally and uniformly mixing the two solutions, and performing electrospinning.

Abstract: The invention relates to compositions, implantable devices and methods related to tissue engineering. Provided is a composition comprising (i) at least one biocompatible polymer suitable for use in tissue-engineering scaffolds and (ii) at least one metal peroxide. Also provided is an implantable device comprising said composition, and methods for tissue engineering comprising the use of the device.

Abstract: An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/?-tricalcium phosphate composite material is composed of ?-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) with mass ratio of 1:10-1:100, in which the ?-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix. The preparation method includes that poly (glycolic acid-L-lysine-L-lactic acid) is polymerized with GRGDY short peptide (glycin-arginine-glycin-aspartic acid-tyrosine sequence) to obtain RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), and then RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is compounded with ?-tricalcium phosphate particles.

Abstract: An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/?-tricalcium phosphate composite material is composed of ?-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) with mass ratio of 1:10-1:100, in which the ?-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix. The preparation method includes that poly (glycolic acid-L-lysine-L-lactic acid) is polymerized with GRGDY short peptide (glycin-arginine-glycin-aspartic acid-tyrosine sequence) to obtain RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), and then RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is compounded with ?-tricalcium phosphate particles.