Patents by Inventor Hongling SHI

Hongling SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12002551
    Abstract: The present invention discloses a method of constructing a pharmacophore to determine whether a molecule is a peroxisome proliferator-activated receptor ? full agonist, partial agonist or antagonist in terms of a binding energy or a free energy surface comprising: providing a protein receptor mimicking said peroxisome proliferator-activated receptor ? and a corresponding ligand; docking the corresponding ligand and the protein receptor to form a docked conformation; performing at least two rounds of molecular dynamic simulation to obtain at least one trajectory and at least one free energy surface; inputting the trajectory to construct at least one pharmacophore and obtaining the binding energy of the corresponding ligand; comparing the molecule with the corresponding ligand in terms of the binding energy thereof to the protein receptor in order to determine whether the molecule is the peroxisome proliferator-activated receptor ? full agonist, partial agonist or antagonist.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: June 4, 2024
    Assignee: Nanjing University
    Inventors: Hongling Liu, Laihao Shi
  • Publication number: 20240083677
    Abstract: An apparatus of salt cavern gas storage without cushion gas includes: a salt cavern; sediments; a drainage assembly; a gas injection and production pipe; a debrining string, one end of which is connected to the drainage assembly, and the other end of which protrudes from the ground to be connected to a water source assembly; a communicating assembly, which is used to make the gas injection and production pipe be in communication with the debrining string on the ground. A closed loop is formed by making the gas injection and production pipe and the debrining string be in communication with each other on the ground through the communicating assembly, thus the non-cushion gas injection-production operation of sediment particles in the salt cavern is realized.
    Type: Application
    Filed: November 5, 2022
    Publication date: March 14, 2024
    Applicant: INSTITUTE OF ROCK AND SOIL MECHANICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Xilin SHI, Xinxing WEI, Yinping LI, Hongling MA, Peng LI, Chunhe YANG, Weizheng BAI
  • Patent number: 11326318
    Abstract: Provided is a lateral water intake structure for preventing silting of bed load and floating debris, which is provided at a river bank. The lateral water intake structure includes: a diversion canal, a guiding wall structure, a shaft-shaped water intaking space, and a trash rack. The lateral water intake structure functions to prevent the floating debris from gathering at the surface of the trash rack and reduce a risk that the trash rack is damaged by water pressure and hitting of the floating debris. Meanwhile, by using a water flow in the watercourse to continuously wash the floating debris near the trash rack, maintenance costs of removing the floating debris at the trash rack manually or mechanically can be reduced.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: May 10, 2022
    Assignees: China Institute of Water Resources and Hydropower Research, China Yangtze Power Co., Ltd.
    Inventors: Dangwei Wang, Anjun Deng, Ye Yin, Qingchao Guo, Xinlei Guo, Tianjie Lei, Hantao Wang, Cuihua Chen, Hongling Shi, Qin Lu
  • Publication number: 20220064888
    Abstract: Provided is a lateral water intake structure for preventing silting of bed load and floating debris, which is provided at a river bank. The lateral water intake structure includes: a diversion canal, a guiding wall structure, a shaft-shaped water intaking space, and a trash rack. The lateral water intake structure functions to prevent the floating debris from gathering at the surface of the trash rack and reduce a risk that the trash rack is damaged by water pressure and hitting of the floating debris. Meanwhile, by using a water flow in the watercourse to continuously wash the floating debris near the trash rack, maintenance costs of removing the floating debris at the trash rack manually or mechanically can be reduced.
    Type: Application
    Filed: January 14, 2021
    Publication date: March 3, 2022
    Inventors: Dangwei Wang, Anjun Deng, Ye Yin, Qingchao Guo, Xinlei Guo, Tianjie Lei, Hantao Wang, Cuihua Chen, Hongling Shi, Qin Lu
  • Publication number: 20210133005
    Abstract: This operating system (101) for a sensor of sensor network is configured in a manner which comprises, in addition to a plurality of generic system functionalities for virtualisation of hardware resources of the sensor, comprising in particular radio-communication functionalities (112) and routing functionalities (114), a plurality of application functionalities (122), each functionality being defined by a software actor (124, 126), each software actor consisting of a finite state automaton, the execution of the various actors being defined in a predetermined scheduling sequence determining the temporal order of the call up of each actor during the course of an execution cycle.
    Type: Application
    Filed: February 16, 2017
    Publication date: May 6, 2021
    Inventors: Kun Mean HOU, Christophe DE VAULX, Xunxing DIAO, Hongling SHI