Abstract: Provided is a binding molecule specific for LIF and use thereof. Specifically, provided is an isolated antibody or an antigen-binding fragment thereof that binds to LIF and inhibits the activity of LIF. Also provided are uses of the isolated antibody or the antigen-binding fragment thereof in treatment of diseases.

Abstract: Provided herein are compound-linker constructs and antibody-drug-conjugates of compounds of formula (Y-1), (Y-2), (Y-3), (A), (B), (C), I, II, III, IV or V that are useful as modulators of STING (Stimulator of Interferon Genes). Also provided are synthesis, compositions and uses of such compound-linker constructs and antibody-drug-conjugates.

Abstract: The present application relates to the technical field of electrophoretic particles, more particularly to an electrophoretic particle, a preparation method therefor, and an application thereof. The electrophoretic particle includes a shell layer and a core layer, which is wrapped in the shell layer. The core layer includes a plurality of core particles, and the density of the core particles is lower than a density of the shell layer. The structure of the plurality of the core particles makes the shell layer wrapping on surfaces of the plurality of the core particles form a folded structure, thus increasing a surface area of the core layer and improving the bonding tightness between the shell layer and the core layer, and making the shell layer of the resulting electrophoretic particle have relatively strong tightness.

Abstract: A method for detecting the monosaccharide and oligosaccharide content and fingerprint spectrum of a compound Sophora flavescens injection, comprising: carrying out detection by using a high-performance liquid chromatography-evaporation light scattering detection method, wherein the monosaccharides and oligosaccharides are D-anhydrous glucose, D-fructose, sucrose and pinitol. The present method is an improved method for detecting monosaccharides and oligosaccharides of a compound Sophora flavescens injection, and can measure four saccharide components in the compound Sophora flavescens injection at the same time, and constructs an HPLC-ELSD fingerprint spectrum to provide a technical method for the quality control of the saccharide components in the compound Sophora flavescens injection.

Abstract: Provided is a binding molecule specifically for CD39 and the use thereof. Specifically, provided is an antibody that binds to CD39 and inhibits the activity of CD39 or an antigen binding part thereof, the use of the antibody or the antigen binding part thereof in the treatment of diseases, a nucleic acid molecule encoding the antibody or the antigen binding part thereof, an expression vector for expressing the antibody or the antigen binding part thereof, a host cell, and a preparation method.

Abstract: A binding molecule specific for CD73 and a use of the binding molecule. Specifically, provided are a separate antibody binding CD73 and inhibiting the activity of CD73 or an antigen binding part of the separate antibody, and a use of the separate antibody or the antigen binding part thereof in treatment of diseases; also provided are a nucleic acid molecule encoding the separate antibody or the antigen binding part thereof, an expression vector for expressing the separate antibody or the antigen binding part thereof, a host cell, and a preparation method.

Abstract: Provided is a binding molecule specific for LIF and use thereof. Specifically, provided is an isolated antibody or an antigen-binding fragment thereof that binds to LIF and inhibits the activity of LIF. Also provided are uses of the isolated antibody or the antigen-binding fragment thereof in treatment of diseases.

Abstract: A binding molecule specific for CD73 and a use of the binding molecule. Specifically, provided are a separate antibody binding CD73 and inhibiting the activity of CD73 or an antigen binding part of the separate antibody, and a use of the separate antibody or the antigen binding part thereof in treatment of diseases; also provided are a nucleic acid molecule encoding the separate antibody or the antigen binding part thereof, an expression vector for expressing the separate antibody or the antigen binding part thereof, a host cell, and a preparation method.

Abstract: A binding molecule specific for CD73 and a use of the binding molecule. Specifically, provided are a separate antibody binding CD73 and inhibiting the activity of CD73 or an antigen binding part of the separate antibody, and a use of the separate antibody or the antigen binding part thereof in treatment of diseases; also provided are a nucleic acid molecule encoding the separate antibody or the antigen binding part thereof, an expression vector for expressing the separate antibody or the antigen binding part thereof, a host cell, and a preparation method.

Abstract: The present disclosure provides an image processing apparatus, an image processing method and a display apparatus. Where the image processing method includes: receiving a signal of an image to be displayed; correcting the grayscale of each pixel in the image to be displayed according to a pre-created correction data table including pixel positions, display correction data and edge correction data; and displaying according to the corrected grayscale of each pixel.

Abstract: A method to improve display performance at edges of a circular display screen is provided. The method comprises determining an edge area and a central area of the circular display screen, the edge area surrounding the central area; along a direction from a geometric center of the circular display screen to the edge area of the circular display screen, dividing the edge area into n display regions each having a different luminance-level, where n is a positive integer larger than 1; and according to luminance of pixels in the central area and the luminance-level of each of the n display regions, adjusting the luminance of the pixels in each of the n display regions to corresponding target luminance. Along the direction from the geometric center to the edge area of the circular display screen, the corresponding target luminance of the pixels in the n display regions sequentially decreases.

Abstract: The present disclosure provides an image processing apparatus, an image processing method and a display apparatus. Where the image processing method includes: receiving a signal of an image to be displayed; correcting the grayscale of each pixel in the image to be displayed according to a pre-created correction data table including pixel positions, display correction data and edge correction data; and displaying according to the corrected grayscale of each pixel.

Abstract: A method to improve display performance at edges of a circular display screen is provided. The method comprises determining an edge area and a central area of the circular display screen, the edge area surrounding the central area; along a direction from a geometric center of the circular display screen to the edge area of the circular display screen, dividing the edge area into n display regions each having a different luminance-level, where n is a positive integer larger than 1; and according to luminance of pixels in the central area and the luminance-level of each of the n display regions, adjusting the luminance of the pixels in each of the n display regions to corresponding target luminance. Along the direction from the geometric center to the edge area of the circular display screen, the corresponding target luminance of the pixels in the n display regions sequentially decreases.