Abstract: Disclosed is a compound of formula (I) and (II) or a pharmaceutically acceptable salt, prodrug, tautomer or stereoisomer, and solvate thereof. The compound can be applied to treatment of cancers and inflammations of mammals. Further disclosed are a preparation method for the compound of formula (I) and (II) and a pharmaceutical composition containing the compound.

Abstract: A comprehensive geological-engineering classification evaluation method for low-permeability reservoirs, includes: constructing geological classification evaluation indexes of a reservoir: adopting gray correlation method to obtain main controlling factors of reservoir geology of the low-permeability reservoirs that affects fracturing effects; based on the main controlling factors of the reservoir geology, constructing the geological classification evaluation indexes of low-permeability reservoirs by principal component analysis; constructing engineering classification evaluation indexes of the reservoir: adopting gray correlation method to obtain main controlling factors of geomechanics of the low-permeability reservoirs that affects fracturing effects; based on the main controlling factors of geomechanics, constructing the engineering classification evaluation indexes of low-permeability reservoirs by an analytic hierarchy process; and according to classification limit values of the geological classificatio

Abstract: A one-machine multi-control method is provided. The method is applied to a master control terminal, including: in response to a touch operation on a graphical user interface of the master control terminal, converting an operation event corresponding to the touch operation into an operation protocol packet by means of a master toolkit; and sending a message to a slave control terminal, the message carrying the operation protocol packet to trigger the slave control terminal to perform the touch operation on the basis of the operation protocol packet by means of a salve toolkit.

Abstract: The present disclosure provides use of transferrin, a transferrin receptor and an antibody thereof in the preparation of an anti-SARS-CoV-2 drug. Use of the transferrin, the transferrin receptor or the transferrin receptor antibody in the preparation of an anti-SARS-CoV-2 drug is provided. Both surface plasmon resonance (SPR) and immunofluorescence confirm that the SARS-CoV-2 binds to the transferrin receptor through SARS-CoV-2 spike protein; the transferrin and/or the transferrin receptor antibody competitively bind(s) to the transferrin receptor of the body, or the transferrin receptor competitively binds to a site of the SARS-CoV-2 to inhibit binding of the SARS-CoV-2 to the transferrin receptor of the body; thus, the opportunity that the SARS-CoV-2 infects cells is blocked, and the antiviral effect of the body is realized.

Abstract: A comprehensive geological-engineering classification evaluation method for low-permeability reservoirs, includes: constructing geological classification evaluation indexes of a reservoir: adopting gray correlation method to obtain main controlling factors of reservoir geology of the low-permeability reservoirs that affects fracturing effects; based on the main controlling factors of the reservoir geology, constructing the geological classification evaluation indexes of low-permeability reservoirs by principal component analysis; constructing engineering classification evaluation indexes of the reservoir: adopting gray correlation method to obtain main controlling factors of geomechanics of the low-permeability reservoirs that affects fracturing effects; based on the main controlling factors of geomechanics, constructing the engineering classification evaluation indexes of low-permeability reservoirs by an analytic hierarchy process; and according to classification limit values of the geological classificatio

Abstract: The present disclosure provides a fine identification method of a tight reservoir fracture based on conventional logging data. The method includes: eliminating a logging interference factor from a non-fracture response, choosing a basic lithological background for fracture identification, analyzing logging response features on different fracture scales, analyzing fracture aperture and filling features on a scale that can be identified by conventional logging data, identifying occurrence of an open fracture, and identifying a development degree of a fracture through a relative amplitude difference between a deep resistivity and a bedrock resistivity. The method of the present disclosure is suited for fine evaluation of a tight reservoir fracture.

Abstract: A method of treating intrauterine inflammation in a subject associated with intrauterine bacterial infection includes administering to the subject a therapeutically effective amount of a toll-like receptor 4 antagonist. The therapeutically effective amount administered to the subject is an amount effective in reducing intrauterine inflammation in the subject.

Abstract: A method of treating intrauterine inflammation in a subject associated with intrauterine bacterial infection includes administering to the subject a therapeutically effective amount of a toll-like receptor 4 antagonist. The therapeutically effective amount administered to the subject is an amount effective in reducing intrauterine inflammation in the subject.