Patents by Inventor Hongtao Lu

Hongtao Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240380027
    Abstract: A liquid-cooling pipeline for an energy storage system, a liquid-cooling system for an energy storage system, and an energy storage device are provided in the present invention.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 14, 2024
    Inventors: Hongtao Lu, Nina Wen
  • Publication number: 20240336686
    Abstract: The present disclosure provides multi-specific molecules specific for SIPR-alpha and one or more target antigens, isolated polynucleotide encoding the same, pharmaceutical compositions comprising the same, and the uses thereof. The present disclosure provides the multi-specific molecule provided comprises a SIRP-alpha binding domain, an activating receptor-binding domain comprising an Fc domain, and a target antigen binding domain.
    Type: Application
    Filed: July 28, 2022
    Publication date: October 10, 2024
    Inventors: Hongtao LU, Dawei SUN, Yanan GENG, Jing WANG, Haixia JIANG, Zhihao WU, Rui GAO, Xiaofeng NIU, Yangsheng QIU
  • Publication number: 20240270839
    Abstract: Provided are anti-CLDN18 (in particular, anti-CLDN18.2) antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical composition comprising the same and the uses thereof.
    Type: Application
    Filed: September 26, 2021
    Publication date: August 15, 2024
    Inventors: Yangsheng QIU, Hongtao LU, Roumei XING, Jingfeng YU, Rui GAO
  • Publication number: 20230416394
    Abstract: Provided are conjugate molecules comprising a CD39 inhibitory portion capable of interfering interaction between CD39 and its substrate, and a TGF ? inhibitory portion capable of interfering interaction between TGF ? and its receptor, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: November 25, 2021
    Publication date: December 28, 2023
    Inventors: Dawei SUN, Zhihao WU, Jun SUN, Yanan GENG, Rui GAO, Lili TANG, Qinglin DU, Yangsheng QIU, Robert H. ARCH, Hongtao LU
  • Patent number: 11267885
    Abstract: Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: March 8, 2022
    Assignee: ZLIP HOLDING LIMITED
    Inventors: Yangsheng Qiu, Jing Li, Honghai Gao, Fenglan Wu, Xu Fang, Shou Li, Hongtao Lu, James S. Yan, Lei Shi
  • Patent number: 11207628
    Abstract: Sulphuric acid plants, separators for separating entrainment for process gas, and gas treatment processes for generating sulphuric acid are provided. The sulphuric acid plant comprises a source of process gas, an entrainment eliminator, a gas rotator located downstream of the gas-liquid contactor, and a separator located downstream of the entrainment eliminator and upstream of the gas rotator. The separator comprises a plurality of passages. Each passage comprises a vane extending longitudinally along the passage, wherein each vane rotates a process gas flowing through the separator. The process comprises transferring process gas from an entrainment eliminator to a separator located downstream of the entrainment eliminator, rotating the process gas through the separator to separate entrainment, and transferring the separated process gas from the separator to rotating equipment located downstream of the separator.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: December 28, 2021
    Assignee: NORAM Engineering and Constructors Ltd.
    Inventors: Christopher Lane, Hongtao Lu, Brian Robert Ferris, Andrés Mahecha-Botero, Bradley Wayne Morrison, Jatinderpal Singh Sandhu, Inez Karina Tanu, Charles Guy Cooper
  • Publication number: 20210388105
    Abstract: Provided are anti-CD39 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 16, 2021
    Inventors: Yangsheng QIU, Meiling SUN, Roumei XING, Dan XU, Yufei SHI, Jinfeng ZHAO, Qinglin DU, Zhihao WU, Rui GAO, Robert H. ARCH, Hongtao LU
  • Publication number: 20210347908
    Abstract: Provided are anti-SIRP? antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 18, 2020
    Publication date: November 11, 2021
    Inventors: Xiaofeng NIU, Jingfeng YU, Jinfeng ZHAO, Fengli WANG, Dan XU, Roumei XING, Zhihao WU, Qinglin DU, Yangsheng QIU, Robert H. ARCH, Hongtao LU
  • Patent number: 10778570
    Abstract: In a network protection method, a network node, and a communications system provided in embodiments of the present disclosure, when signal degrade or signal fail occurs in a service transmission path, a communication status of a source node of a current protection segment is obtained, and whether to perform protection switching is determined according to the communication status of the source node and a communication status of a local communication path. This can avoid erroneous switching to some extent, thereby improving protection switching accuracy of a communications network.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: September 15, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jun Yan, Zhiquan Liao, Tianhai Chang, Hongtao Lu, Min Chen, Qian Xiong
  • Publication number: 20200247886
    Abstract: Disclosed herein are antigen binding units that specifically bind to CD47. Further disclosed herein are polynucleic acids encoding said antigen binding units, vectors comprising said polynucleic acids, and hybridomas and host cells comprising said vectors. Further provided herein are methods for inducing phagocytosis of CD47-expressing cells.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 6, 2020
    Inventors: Yangsheng QIU, Jing LI, Honghai GAO, Fenglan WU, Xu FANG, Shou LI, Hongtao Lu, James S. YAN, Lei SHI
  • Publication number: 20200101407
    Abstract: Sulphuric acid plants, separators for separating entrainment for process gas, and gas treatment processes for generating sulphuric acid are provided. The sulphuric acid plant comprises a source of process gas, an entrainment eliminator, a gas rotator located downstream of the gas-liquid contactor, and a separator located downstream of the entrainment eliminator and upstream of the gas rotator. The separator comprises a plurality of passages. Each passage comprises a vane extending longitudinally along the passage, wherein each vane rotates a process gas flowing through the separator. The process comprises transferring process gas from an entrainment eliminator to a separator located downstream of the entrainment eliminator, rotating the process gas through the separator to separate entrainment, and transferring the separated process gas from the separator to rotating equipment located downstream of the separator.
    Type: Application
    Filed: September 26, 2019
    Publication date: April 2, 2020
    Inventors: Christopher LANE, Hongtao LU, Brian Robert FERRIS, Andrés MAHECHA-BOTERO, Bradley Wayne MORRISON, Jatinderpal Singh SANDHU, Inez Karina TANU, Charles Guy COOPER
  • Publication number: 20180109445
    Abstract: In a network protection method, a network node, and a communications system provided in embodiments of the present disclosure, when signal degrade or signal fail occurs in a service transmission path, a communication status of a source node of a current protection segment is obtained, and whether to perform protection switching is determined according to the communication status of the source node and a communication status of a local communication path. This can avoid erroneous switching to some extent, thereby improving protection switching accuracy of a communications network.
    Type: Application
    Filed: December 7, 2017
    Publication date: April 19, 2018
    Inventors: Jun Yan, Zhiquan Liao, Tianhai Chang, Hongtao Lu, Min Chen, Qian Xiong
  • Publication number: 20150080380
    Abstract: This invention relates to novel therapeutic uses for compounds which are inverse agonists of the H3 receptor. In particular this invention relates to therapeutic use of these compounds in the treatment of Multiple Sclerosis.
    Type: Application
    Filed: January 15, 2013
    Publication date: March 19, 2015
    Inventors: Hongtao Lu, Rong Wang
  • Publication number: 20110287000
    Abstract: The present invention provides novel methods of treatment of multiple sclerosis and other autoimmune diseases or inflammatory disorders, and antagonists, including isolated binding proteins for use in the novel methods. There is provided a method of treating multiple sclerosis comprising the neutralization of the biological activity of IL-7 by binding to CD127 or IL-7. The isolated binding proteins may also neutralize the biological activity of TSLP.
    Type: Application
    Filed: August 7, 2009
    Publication date: November 24, 2011
    Inventors: Stewart Leung, Lixin Li, Xuebin Liu, Hongtao Lu, Ping Tsui, Jingwu Zang
  • Publication number: 20100040616
    Abstract: The present invention provides novel methods of treatment of multiple sclerosis and other autoimmune diseases or inflammatory disorders, and antagonists, including isolated binding proteins for use in the novel methods. There is provided a method of treating multiple sclerosis comprising the neutralization of the biological activity of IL-7 by binding to CD127 or IL-7. The isolated binding proteins may also neutralize the biological activity of TSLP.
    Type: Application
    Filed: August 7, 2009
    Publication date: February 18, 2010
    Inventors: Stewart LEUNG, Lixin Li, Xuebin Liu, Hongtao Lu, Ping Tsui, Jingwu Zang
  • Publication number: 20050016882
    Abstract: An optometric trial lens set, a bifurcated case therefor, and method of use thereof are disclosed. Preferably, the case includes a first compartment, a second compartment, and a divider caddy therebetween. The first compartment is preferably configured to retain the trial lens set whereas the second compartment and the divider caddy are configured to retain a plurality of optometric instruments. Optionally, an electroluminance lamp index system is provided to enable an eye-care professional to identify components of the trial lens set in partial or complete darkness.
    Type: Application
    Filed: July 7, 2003
    Publication date: January 27, 2005
    Inventors: Ravindra Kankaria, Hongtao Lu