Patents by Inventor Hongwei Gu
Hongwei Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156689Abstract: A pressed powder product and a method for preparing the same are provided. The pressed powder product includes a pressed powder layer, an ink absorbing layer and a pattern layer. The pattern layer is obtained by printing. The ink absorbing layer is formed by spraying an ink-absorbing paint on the pressed powder layer. The ink-absorbing paint includes 0.5% to 10% by weight of an oil controlling agent, 0.5% to 20% by weight of a color developing agent, 55% to 98.5% by weight of a solvent, and 0.5% to 10% by weight of a stabilizer. The method for preparing the pressed powder product includes: uniformly mixing an oil controlling agent, a color developing agent, a solvent, and a stabilizer to obtain the mixture; spraying the mixture on a pressed powder layer, and drying to obtain a semi-manufactured pressed powder product; and, printing a pattern on the semi-manufactured pressed powder product.Type: ApplicationFiled: May 25, 2023Publication date: May 16, 2024Inventors: Hongwei GU, Haifeng QIN, Huaicheng YU
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Patent number: 10273481Abstract: Provided is an siRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia, and particularly, provided are a method of a tandem expression for siRNA of BTK, and an siRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia.Type: GrantFiled: January 29, 2015Date of Patent: April 30, 2019Assignee: Jiangsu Mircromedmark Biotech Co., LTD.Inventors: Chenyu Zhang, Ke Zeng, Hongwei Gu, Xueliang Wang
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Patent number: 9909127Abstract: Provided is non-coded RNA of in-vivo infected microorganisms, parasitic microorganisms, symbiotic microorganisms and identification and application thereof. Also provided is a method of identifying the non-coded RNA of in-vivo pathogen sources. The invention also provided a pharmaceutical composition containing an inhibitor for specifically inhibiting or blocking a RNA sequence and a method to treat a pathogen infectious disease or parasitic disease by administering an inhibitor, which inhibits a non-coding RNA sequence derived from a pathogen in the body of an animal, to an animal subject in need thereof.Type: GrantFiled: December 9, 2014Date of Patent: March 6, 2018Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu Zhang, Ke Zeng, Jin Wang, Xihan Li, Hongwei Gu
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Patent number: 9903002Abstract: The present invention provides Salmonella non-coding RNA and the identification and application thereof. In particular, the present invention proves through experiments that a Salmonella bacterium delivers non-coding RNAs (ncRNAs) encoded by the bacterium itself into a host cell, generates milRNAs similar to microRNAs by means of a microRNA splicing system in the cell, regulates the immune system with the milRNAs, and further protects the Salmonella bacterium from being cleared by the host. Adsorbing milRNAs using milRNA inhibitors can effectively inhibit the survival ability of the bacterium in the cell, leading to a reduced vitality of the bacterium. The present invention further provides relevant reagents and methods for effective detection of, treatment to and study on Salmonella bacteria or Salmonella infectious diseases.Type: GrantFiled: December 9, 2014Date of Patent: February 27, 2018Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.Inventors: Ke Zeng, Hongwei Gu, Chenyu Zhang, Tianfu Zhang
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Publication number: 20170044549Abstract: Provided is an siRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia, and particularly, provided are a method of a tandem expression for siRNA of BTK, and an siRNA in tandem expression and uses thereof in treating chronic lymphocytic leukemia.Type: ApplicationFiled: January 29, 2015Publication date: February 16, 2017Applicant: Jiangsu Micromedmark Biotech Co., LTD.Inventors: Chenyu Zhang, Ke Zeng, Hongwei Gu, Xueliang Wang
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Publication number: 20160319332Abstract: The present invention provides Salmonella non-coding RNA and the identification and application thereof. In particular, the present invention proves through experiments that a Salmonella bacterium delivers non-coding RNAs (ncRNAs) encoded by the bacterium itself into a host cell, generates milRNAs similar to microRNAs by means of a microRNA splicing system in the cell, regulates the immune system with the milRNAs, and further protects the Salmonella bacterium from being cleared by the host. Adsorbing milRNAs using milRNA inhibitors can effectively inhibit the survival ability of the bacterium in the cell, leading to a reduced vitality of the bacterium. The present invention further provides relevant reagents and methods for effective detection of, treatment to and study on Salmonella bacteria or Salmonella infectious diseases.Type: ApplicationFiled: December 9, 2014Publication date: November 3, 2016Applicant: JIANGSU MICROMEDMARK BIOTECH CO. LTD.Inventors: Ke ZENG, Hongwei GU, Chenyu ZHANG, Tianfu ZHANG
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Publication number: 20160312221Abstract: Provided is non-coded RNA of in-vivo infected microorganisms, parasitic microorganisms, symbiotic microorganisms and identification and application thereof. Also provided is a method of identifying the non-coded RNA of in-vivo pathogen sources.Type: ApplicationFiled: December 9, 2014Publication date: October 27, 2016Applicant: JIANGSU MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu ZHANG, Ke ZENG, Jin WANG, Xihan LI, Hongwei GU
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Patent number: 9421167Abstract: The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a preparation method of the drug.Type: GrantFiled: December 9, 2010Date of Patent: August 23, 2016Assignee: Micromedmark Biotech Co. Ltd.Inventors: Chenyu Zhang, Ke Zeng, Hongwei Gu, Minghui Cao, Liming Li
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Patent number: 9376679Abstract: Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.Type: GrantFiled: May 26, 2010Date of Patent: June 28, 2016Assignee: Micromedmark Biotech Co. Ltd.Inventors: Chenyu Zhang, Ke Zeng, Danqing Liu, Yujing Zhang, Hongwei Gu
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Publication number: 20140302119Abstract: Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.Type: ApplicationFiled: May 26, 2010Publication date: October 9, 2014Applicant: Micromedmark Biotech Co. Ltd.Inventors: Chenyu Zhang, Ke Zeng, Danqing Liu, Yujing Zhang, Hongwei Gu
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Publication number: 20130209544Abstract: Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles containing interfering RNAs are also provided. Microvesicles containing interfering RNAs, pharmaceutical compositions and kits comprising such microvesicles can be used to study the effects of interfering RNAs on receptor cells. As microvesicles containing interfering RNAs can stably, high efficiently and specifically deliver interfering RNAs, microvesicles containing interfering RNAs can be used to treat related diseases.Type: ApplicationFiled: May 26, 2010Publication date: August 15, 2013Applicants: JIANGSU MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu Zhang, Ke Zeng, Danqing Liu, Yujing Zhang, Hongwei Gu
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Publication number: 20130203837Abstract: The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a preparation method of the drug.Type: ApplicationFiled: December 9, 2010Publication date: August 8, 2013Inventors: Chenyu Zhang, Ke Zeng, Hongwei Gu, Minghui Cao, Liming Li
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Patent number: 8456073Abstract: The present invention provides devices comprising an assembly of carbon nanotubes, and related methods. In some cases, the carbon nanotubes may have enhanced alignment. Devices of the invention may comprise features and/or components which may enhance the emission of electrons and may lower the operating voltage of the devices. Using methods described herein, carbon nanotube assemblies may be manufactured rapidly, at low cost, and over a large surface area. Such devices may be useful in display applications such as field emission devices, or other applications requiring high image quality, low power consumption, and stability over a wide temperature range.Type: GrantFiled: May 29, 2009Date of Patent: June 4, 2013Assignee: Massachusetts Institute of TechnologyInventors: Timothy M. Swager, Hongwei Gu
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Publication number: 20130113359Abstract: The present invention provides devices comprising an assembly of carbon nanotubes, and related methods. In some cases, the carbon nanotubes may have enhanced alignment. Devices of the invention may comprise features and/or components which may enhance the emission of electrons and may lower the operating voltage of the devices. Using methods described herein, carbon nanotube assemblies may be manufactured rapidly, at low cost, and over a large surface area. Such devices may be useful in display applications such as field emission devices, or other applications requiring high image quality, low power consumption, and stability over a wide to temperature range.Type: ApplicationFiled: May 29, 2009Publication date: May 9, 2013Applicant: Massachusetts Institute of TechnologyInventors: Timothy M. Swager, Hongwei Gu
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Publication number: 20120136164Abstract: The invention relates to a nanoparticulate material comprising long ultrathin metal nanowires, and to processes for making it. The nanoparticulate material may be used as a catalyst and, in the presence of a chiral modifier, can catalyse enantioselective reactions.Type: ApplicationFiled: March 30, 2010Publication date: May 31, 2012Applicant: Agency for Science, Technology and ResearchInventors: Jackie Y. Ying, Nandanan Erathodiyil, Hongwei Gu, Huilin Shao, Jiang Jiang
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MAGNETITE-SILVER HETERODIMER NANOPARTICLES AND THEIR PREPARATION AND USE FOR TWO-PHOTON FLUORESCENCE
Publication number: 20110233427Abstract: A heterodimer particle is provided which comprises a first component particle comprising magnetite and a second component particle comprising silver. The second component particle may have a structure and a particle size selected to generate two-photon fluorescence emission. The heterodimer particle may be irradiated with light of a wavelength selected to induce two-photon fluorescence emission, which is then detected. Tetramethylammonium hydroxide may be bonded to the surface of the first component and glutathione may be bonded to the surface of the second component. The heterodimer particle may be formed by preparing a magnetite particle and growing a silver particle on the magnetite particle, in the presence of 1,2-dodecanediol as a reducing agent.Type: ApplicationFiled: December 18, 2008Publication date: September 29, 2011Inventors: Jackie Y. Ying, Jiang Jiang, Hongwei Gu, Huilin Shao -
Patent number: 7754444Abstract: This invention provides a method of detecting pathogens comprising the steps of: (a) contacting a sufficient amount of biofunctional magnetic nanoparticles with an appropriate sample for an appropriate period of time to permit the formation of complexes between the pathogens in the sample and the nanoparticles; (b) using a magnetic field to aggregate said complexes; and (c) detecting said complexes. The method may further comprise the additional step of removing said complexes. The biofunctional magnetic nanoparticles are preferably a conjugate of vancomycin and FePt. The pathogens may be bacteria or viruses, and the sample may be a solid, liquid, or gas. Detection may involve conventional fluorescence assay, enzyme-linked immunosorbent assay (ELISA), optical microscope, electron microscope, or a combination thereof. The sensitivity of detection for the method is at least as low as 10 colony forming units (cfu) of the pathogens in one milliliter of solution within one hour.Type: GrantFiled: June 23, 2005Date of Patent: July 13, 2010Assignee: The Hong Kong University of Science and TechnologyInventors: Bing Xu, Pak Leung Ho, Hongwei Gu
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Publication number: 20060292555Abstract: This invention provides a method of detecting pathogens comprising the steps of: (a) contacting a sufficient amount of biofunctional magnetic nanoparticles with an appropriate sample for an appropriate period of time to permit the formation of complexes between the pathogens in the sample and the nanoparticles; (b) using a magnetic field to aggregate said complexes; and (c) detecting said complexes. The method may further comprise the additional step of removing said complexes. The biofunctional magnetic nanoparticles are preferably a conjugate of vancomycin and FePt. The pathogens may be bacteria or viruses, and the sample may be a solid, liquid, or gas. Detection may involve conventional fluorescence assay, enzyme-linked immunosorbent assay (ELISA), optical microscope, electron microscope, or a combination thereof. The sensitivity of detection for the method is at least as low as 10 colony forming units (cfu) of the pathogens in one milliliter of solution within one hour.Type: ApplicationFiled: June 23, 2005Publication date: December 28, 2006Inventors: Bing Xu, Pak Ho, Hongwei Gu