Abstract: A system and method measuring data, from user devices, regarding user interactions with a Software-as-a-Service (SaaS) product installed in each of the user devices, using a measurement module in the processor to generate measured data. The measured data is then modeled as a graph, using a graphing application in the processor, wherein the graph includes a plurality of varying metrics, each representing different attributes of a structure of the graph. A viral effectiveness index (VEI) as a single metric summarizing core graph attributes of the graph is determined from the plurality of the varying metrics of the graph using a viral effectiveness index (VEI) module in an analytics application in the processor.

Abstract: A system and method measuring data, from user devices, regarding user interactions with a Software-as-a-Service (SaaS) product installed in each of the user devices, using a measurement module in the processor to generate measured data. The measured data is then modeled as a graph, using a graphing application in the processor, wherein the graph includes a plurality of varying metrics, each representing different attributes of a structure of the graph. A viral effectiveness index (VEI) as a single metric summarizing core graph attributes of the graph is determined from the plurality of the varying metrics of the graph using a viral effectiveness index (VEI) module in an analytics application in the processor.

Abstract: A method may include accessing, from a data store, telemetry data for an application, the telemetry data identifying actions executed by the application for a set of users of the application; retrieving an engagement index for the application using the telemetry data based on an engagement index profile, the engagement index profile identifying a selection of actions and a set of calculation dimensions; and presenting a user interface, the user interface including: a first portion identifying the selection of actions; a second portion identifying the set of calculation dimensions; a third portion identifying an original value of an action of the selection of actions with respect to a dimension in the set of calculation dimensions; and a fourth portion identifying a weighted composite value of the action with respect to set of calculation dimensions.

Abstract: A method may include accessing, from a data store, telemetry data for an application, the telemetry data identifying actions executed by the application for a set of users of the application; retrieving an engagement index for the application using the telemetry data based on an engagement index profile, the engagement index profile identifying a selection of actions and a set of calculation dimensions; and presenting a user interface, the user interface including: a first portion identifying the selection of actions; a second portion identifying the set of calculation dimensions; a third portion identifying an original value of an action of the selection of actions with respect to a dimension in the set of calculation dimensions; and a fourth portion identifying a weighted composite value of the action with respect to set of calculation dimensions.

Abstract: A multi-targeted siRNA for treating cancers is disclosed. Specifically, an siRNA composition is provided, comprising: a first siRNA molecule that reduces the expression of the first target gene; optionally, a coding sequence targeting a peptide element; and optionally, a second siRNA molecule that reduces the expression of the second target gene, wherein the first target gene is selected from the group consisting of EGFR, KRAS, or a combination thereof, and the siRNA composition reduces the expression of two or more genes. The siRNA or vector provided can be directly injected into the body to treat cancers. A multi-targeted siRNA for treating cancers is disclosed.

Abstract: Provided are a precursor miRNA and application thereof in a tumor treatment. The precursor miRNA from the 5? end to 3? end has a structure presented as formula I: B1 is anti-miRNA-214-5p; B2 is an essentially complementary sequence or a totally complementary sequence to B1, and B2 and C are not complementary; C is a sequence having a stem-loop structure; A1 and A2 are respectively RNA sequences having no or 4-5 bases freely selected bases respectively; the precursor miRNA shown can be processed to form anti-miRNA-214 in a host, and only anti-miRNA-214-5p but not anti-miRNA-214-3p is expressed in the anti-miRNA-214.

Abstract: Provided are an EGFR gene expression-suppressing siRNA, a precursor sequence of same, and uses thereof.

Abstract: The present invention discloses an siRNA that inhibits K-RAS gene expression, and the precursor sequences and applications thereof. The K-RAS siRNA and its precursor sequences provided by the present invention can efficiently inhibit the expression of the K-RAS gene, and in vivo experiments have shown that the K-RAS siRNA has a certain inhibitory effect on tumours highly expressing K-RAS. The precursor of the siRNA of the invention and its vector can form a stable siRNA that functions in a host.

Abstract: The present invention belongs to the field of semiconductor materials preparation technology, and relates to a preparation method of gallium oxide/copper gallium oxide heterojunction. In this method, the gallium oxide is pre-treated before the copper source is deposited on the pre-treated gallium oxide, or directly cover the copper source layer on the pretreated gallium oxide. Then, the gallium oxide with copper source is placed in a high temperature furnace in proper form and then heat treated for a certain time under certain conditions, so that the copper atomics can be controlled to diffuse into gallium oxide to form corresponding copper-gallium-oxygen alloys. Further the copper-gallium-oxygen alloys forms gallium oxide/copper gallium oxide heterojunction having good interfacial properties with gallium oxide which does not undergo copper diffusion. The advantage is that the high quality copper gallium oxide material can be prepared. The required equipment and process are simple and controllable.

Abstract: An X-ray detector based on silicon carbide single crystal as well as its preparation method. The detector mainly includes: high resistivity silicon carbide single crystal, high electron concentration n-type silicon carbide layer, low electron concentration n-type silicon carbide layer, high hole concentration p-type silicon carbide layer, low hole concentration p-type silicon carbide layer, silicon dioxide protection layer, p-type silicon carbide ohmic contact electrode, n-type silicon carbide ohmic contact electrode, and gold lead electrode. The invention provides an effective and simple process manufacturing technology, solves the preparation problem of silicon carbide-based high-energy X-ray detector, and realizes the development of a new silicon carbide radiation detector.

Abstract: An X-ray detector based on silicon carbide single crystal as well as its preparation method. The detector mainly includes: high resistivity silicon carbide single crystal, high electron concentration n-type silicon carbide layer, low electron concentration n-type silicon carbide layer, high hole concentration p-type silicon carbide layer, low hole concentration p-type silicon carbide layer, silicon dioxide protection layer, p-type silicon carbide ohmic contact electrode, n-type silicon carbide ohmic contact electrode, and gold lead electrode. The invention provides an effective and simple process manufacturing technology, solves the preparation problem of silicon carbide-based high-energy X-ray detector, and realizes the development of a new silicon carbide radiation detector.

Abstract: The invention belongs to the technical field of semiconductor material preparation, and in particular provides a preparation method of tin doped n-type gallium oxide. To pre-deposit the appropriate tin doping source on gallium oxide materials in proper ways. The gallium oxide material is then placed in a high temperature tube in an appropriate manner. Then the tin atoms can be controlled to diffuse into the gallium oxide material by heat treatment at a certain temperature for a period of time. Then the tin atoms can be activated as an effective donor to realize the n-type doping of the gallium oxide material. In this invention, the doping can be realized after the preparation of the gallium oxide material is completed, and the necessary equipment and process are simple, and the doping controllability is high.

Abstract: Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5?- to 3?-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.

Abstract: The present invention discloses an siRNA that inhibits K-RAS gene expression, and the precursor sequences and applications thereof. The K-RAS siRNA and its precursor sequences provided by the present invention can efficiently inhibit the expression of the K-RAS gene, and in vivo experiments have shown that the K-RAS siRNA has a certain inhibitory effect on tumours highly expressing K-RAS. The precursor of the siRNA of the invention and its vector can form a stable siRNA that functions in a host.

Abstract: Provided are an EGFR gene expression-suppressing siRNA, a precursor sequence of same, and uses thereof.

Abstract: The invention belongs to the technical field of semiconductor material preparation, and in particular provides a preparation method of tin doped n-type gallium oxide. To pre-deposit the appropriate tin doping source on gallium oxide materials in proper ways. The gallium oxide material is then placed in a high temperature tube in an appropriate manner. Then the tin atoms can be controlled to diffuse into the gallium oxide material by heat treatment at a certain temperature for a period of time. Then the tin atoms can be activated as an effective donor to realize the n-type doping of the gallium oxide material. In this invention, the doping can be realized after the preparation of the gallium oxide material is completed, and the necessary equipment and process are simple, and the doping controllability is high.

Abstract: Provided are a method and use of microRNA MiR-2911 in regulating an ebola virus. Particularly provided are a method and use of isolated microRNA MiR-2911 in regulating an ebola virus protein gene.

Abstract: Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5?- to 3?-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.

Abstract: Provided are a precursor miRNA and application thereof in a tumor treatment. The precursor miRNA from the 5? end to 3? end has a structure presented as formula I: B1 is anti-miRNA-214-5p; B2 is an essentially complementary sequence or a totally complementary sequence to B1, and B2 and C are not complementary; C is a sequence having a stem-loop structure; A1 and A2 are respectively RNA sequences having no or 4-5 bases freely selected bases respectively; the precursor miRNA shown can be processed to form anti-miRNA-214 in a host, and only anti-miRNA-214-5p but not anti-miRNA-214-3p is expressed in the anti-miRNA-214.

Abstract: Provided are a method and use of microRNA MiR-2911 in regulating an ebola virus. Particularly provided are a method and use of isolated microRNA MiR-2911 in regulating an ebola virus protein gene.