Abstract: A battery module including a battery unit and a conductive unit. The battery unit includes at least one cell, and each cell of the battery unit includes a first tab and a second tab having opposite polarities. The conductive unit includes a first conductive member and a second conductive member spaced apart from the first conductive member in a thickness direction of the cell, the first conductive member is electrically connected with the first tab of any cell, and the second conductive member is electrically connected with the second tab of any cell. The battery module is configured that the first conductive member and the second conductive member are in conductive contact through the swelling of the cell.

Abstract: A battery pack is disclosed, including a cover plate, a cell module, a second resin layer, a battery pack housing, and an insulation assembly. The cell module is accommodated in the battery pack housing and fixed by the second resin layer. The cell module includes a plurality of cells. Each of the cells includes a first end and a second end disposed opposite to each other along a first direction. The insulation assembly is disposed at second ends of at least two of the cells. The insulation assembly and the second ends of the at least two cells form a first space. The first space communicates with a clearance between the at least two cells. The insulation assembly closes off one side of the first space. The insulation assembly and the first space form an exhaust passage. The exhaust passage communicates with an outside of the battery pack.

Abstract: A battery pack includes a cell module, a covering, a first resin layer, and at least one first structural member. The cell module includes a plurality of cell assemblies stacked along a first direction, a first surface, a second surface, a first lateral face and a second lateral face, a first region and a second region located on two sides of the covering respectively along a second direction. The covering includes a first section, a second section, and a third section. The first section covers at least a part of the first lateral face. The second section covers at least a part of the second lateral face. The third section covers the first surface. The first resin layer is disposed in the first region. The first structural member is disposed between two adjacent cell assemblies to partition the two adjacent cell assemblies.

Abstract: A battery pack includes: a cover plate, a cell module, a first resin layer, a battery pack housing, and at least one first monitoring member. The cell module is accommodated inside the battery pack housing and fastened by the first resin layer, the cover plate is fastened to the battery pack housing, the cell module includes a plurality of cells stacked in a first direction. Each cell includes an electrode assembly, a cell housing configured to accommodate the electrode assembly, and a tab electrically connected to the electrode assembly. The cell housing includes a sealing portion, and the tab extends out of the cell housing from the sealing portion in a second direction. One of the at least one first monitoring member is disposed between sealing portions of the adjacent cells. The first monitoring member is connected to the cell module and monitor temperature of the tab of the cell.

Abstract: A battery including a housing and a cell assembly disposed inside the housing, and the cell assembly includes a plurality of stacked cell units. The cell assembly further includes a fastening band, a first separator, and a fixing plate. The fastening band is disposed on an exterior surface of the cell assembly and is configured to limit an external expansion volume of the cell assembly. The first separator and the fixing plate are disposed on two opposite side surfaces of the cell assembly along a stacking direction of the cell units and are located on an exterior surface of the fastening band, and the first separator is sandwiched between the fastening band and the fixing plat.

Abstract: A battery cell module includes a plurality of stacked battery cells, a collection member, and a bracket. The battery cell includes tabs and a cell body; and the collection member is connected to the tabs; where in two adjacent battery cells, a first battery cell includes a first tab and a second tab, the second battery cell includes a third tab and a fourth tab, and the first tab is connected to the third tab. The bracket includes a fixing plate and a first barrier provided on the fixing plate, where the collection member is provided between the fixing plate and the cell body; and the first barrier is provided between the second tab of the first battery cell and the fourth tab of the second battery cell.

Abstract: A battery pack with a pressure relief structure, including a housing provided with an accommodating cavity; a cell assembly accommodated in the accommodating cavity; a spacer arranged between a first side of the cell assembly and the housing and provided with an air vent; a pressure relief part arranged on the housing, the pressure relief part being in contact with the spacer or an air channel being formed therebetween; and glue, filled in a gap between at least partial regions outside the first side of the cell assembly and the housing and used for fixing the cell assembly and the housing. The battery pack is provided with the spacer with the air vent, the spacer is arranged between the first side of the cell assembly and the housing.

Abstract: Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

Abstract: The present application relates to a positive-working heat-sensitive lithographic plate. The infrared heat-sensitive image recording composition of the plate comprises a resin having self-dissolution inhibiting property and an infrared absorber. The resin having self-dissolution inhibiting property is an alkali-soluble resin that contains phenolic hydroxyl group, and carbamate or thiocarbamate group that has strong electron-absorbing ability. The advantage of the present application is that it requires no dissolution inhibitor when preparing the infrared positive-working heat-sensitive CTP plate. The mechanism could be understood but not limited to that the carbamate or thiocarbamate group contained in the resin has a dissolution inhibiting effect on the phenolic hydroxyl group in the resin, reducing the solubility of the resin in an alkali solution.

Abstract: Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

Abstract: Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

Abstract: Compounds useful as immunosuppressive, anti-inflammatory and anticancer agents and methods of their preparation and use are described. The compounds are analogs or derivatives of triptolide and related compounds, modified at the 5- and/or 6-position relative to the naturally occurring compounds.

Abstract: Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

Abstract: Compounds useful as immunosuppressive, anti-inflammatory and anticancer agents and methods of their preparation and use are described. The compounds are analogs or derivatives of triptolide and related compounds, modified at the 5- and/or 6-position relative to the naturally occurring compounds.

Abstract: The present invention relates to methods of preparation and use of coumarin and chromene compounds for treating or preventing viral infections.

Abstract: Compounds useful in immunosuppressive, anti-inflammatory and anticancer treatment are described. The compounds are triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.

Abstract: The present invention relates to methods for preparing 2,2-dimethyl-5-acyloxy -10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (5) and 2,2-dimethyl-5-hydroxy-10 -propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (6) and their use as intermediates for the synthesis of antiviral calanolide compounds. For example, Fries rearrangement on compound 5 or Friedel-Crafts reaction on 6, yields intermediate 2,2-dimethyl-5-hydroxy -6-propionyl-10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (4), which, in turn, can be converted to (+)-calanolide A and (−)-calanolide B. The coupling of compound 6 with the appropriate chiral molecule under Mitsunobu or nucleophilic displacement leads to the asymmetric synthesis of antiviral calanolide compounds.

Abstract: The present invention relates to methods for preparing 2,2-dimethyl-5-acyloxy-10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (5) and 2,2-dimethyl-5-hydroxy-10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (6) and their use as intermediates for the synthesis of antiviral calanolide compounds. For example, Fries rearrangement on compound 5 or Friedel-Crafts reaction on 6, yields intermediate 2,2-dimethyl-5-hydroxy-6-propionyl-10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (4), which, in turn, can be converted to (+)-calanolide A and (−)-calanolide B. The coupling of compound 6 with the appropriate chiral molecule under Mitsunobu or nucleophilic displacement leads to the asymmetric synthesis of antiviral calanolide compounds.

Abstract: The present invention relates to methods for preparing 2,2-dimethyl-5-acyloxy-10-propyl-2H,8H-benzo[ 1,2-b:3,4-b ′]dipyran-8-one (5) and 2,2-dimethyl-5-hydroxy- 10-propyl-2H,8H-benzo[1,2-b:3,4-b ′]dipyran-8-one (6) and their use as intermediates for the synthesis of antiviral calanolide compounds. For example, Fries rearrangement on compound 5 or Friedel-Crafts reaction on 6, yields intermediate 2,2-dimethyl-5-hydroxy-6-propionyl-10-propyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-8-one (4), which, in turn, can be converted to (+)-calanolide A and (−)-calanolide B. The coupling of compound 6 with the appropriate chiral molecule under Mitsunobu or nucleophilic displacement leads to the asymmetric synthesis of antiviral calanolide compounds.