Patents by Inventor Hongwu Liu

Hongwu Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250057999
    Abstract: Provided is a glutamic acid (Glu)-urea compound and a preparation method and use thereof. The Glu-urea compound and the nuclide-targeted probe have excellent in vivo biological properties and show a high specific uptake in lesions with high expression of a prostate-specific membrane antigen (PSMA) protein. The compound and probe have a high target/non-target ratio, low non-specific background activity, and significantly-enhanced tumor uptake and retention time. The compound and probe are suitable for use in the nuclide therapy and imaging of tumors, and can also reduce unnecessary radiation damage to normal tissues and organs. The compound and probe can also overcome the shortcomings such as low target organ uptake and short retention time of small-molecule PSMA, and improve the effects of PSMA-targeted nuclide therapy and imaging, thus exhibiting a potential to be widely used in clinical applications.
    Type: Application
    Filed: September 23, 2024
    Publication date: February 20, 2025
    Inventors: Zhide GUO, Xingxing CHENG, Xianzhong ZHANG, Hongwu LIU, Xueqi WANG
  • Patent number: 11795635
    Abstract: An intelligent integrated anti-collision system and method for a pier, including: a radar sensing device disposed at the joint between the pier and a girder, image collection devices disposed around the pier, control system, hydraulic system and execution device, where the radar sensing and image collection devices transmit collected signals to the control system, which uses the hydraulic system to control the action of the execution device; the execution device is disposed at a middle part of the pier and includes a plurality of sections of steel-reinforced rubber concrete girder connected end to end through pulleys, the hydraulic system can drive the pulleys to rotate to enable the sections to be located on the same horizontal line, and an energy dissipation apparatus is disposed at the tail end of the last section to realize energy dissipation of the energy generated by impact when an object impacts the energy dissipation apparatus.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: October 24, 2023
    Assignee: SHANDONG UNIVERSITY
    Inventors: Zeying Yang, Jianbo Qu, Shucai Li, Qingsong Zhang, Zhi Ge, Xiaoyan Ding, Hongwu Liu, Fengjin Zhao, Yuhui Shan, Xiaobin Fan, Peng Zhang, Xinghua Xi, Youzhi Wang, Hetao Hou, Li Tian, Ke Wu, Yongye Qu, Yalei Zhang
  • Publication number: 20230146650
    Abstract: An intelligent integrated anti-collision system and method for a pier, including: a radar sensing device disposed at the joint between the pier and a girder, image collection devices disposed around the pier, control system, hydraulic system and execution device, where the radar sensing and image collection devices transmit collected signals to the control system, which uses the hydraulic system to control the action of the execution device; the execution device is disposed at a middle part of the pier and includes a plurality of sections of steel-reinforced rubber concrete girder connected end to end through pulleys, the hydraulic system can drive the pulleys to rotate to enable the sections to be located on the same horizontal line, and an energy dissipation apparatus is disposed at the tail end of the last section to realize energy dissipation of the energy generated by impact when an object impacts the energy dissipation apparatus.
    Type: Application
    Filed: June 19, 2019
    Publication date: May 11, 2023
    Applicant: SHANDONG UNIVERSITY
    Inventors: Zeying YANG, Jianbo QU, Shucai LI, Qingsong ZHANG, Zhi GE, Xiaoyan DING, Hongwu LIU, Fengjin ZHAO, Yuhui SHAN, Xiaobin FAN, Peng ZHANG, Xinghua XI, Youzhi WANG, Hetao HOU, Li TIAN, Ke WU, Yongye QU, Yalei ZHANG
  • Patent number: 9310449
    Abstract: Provided is a total electrical nuclear-spin polarization device that is applicable to many narrow-gap semiconductor two-dimensional quantum structures such as InSb with a large g-factor and with a mobility having a normal value. A nuclear-spin polarization device 1 creates a state where the Landau-level separation and the Zeeman-level separation in a sample are equal to each other in a magnetic field, thereby crossing different spin states, and detects nuclear-spin polarization from a resistance change at the crossing point caused by the nuclear-spin polarization.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: April 12, 2016
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Hongwu Liu, Kaifeng Yang, Yoshiro Hirayama
  • Publication number: 20120256629
    Abstract: Provided is a total electrical nuclear-spin polarization device that is applicable to many narrow-gap semiconductor two-dimensional quantum structures such as InSb with a large g-factor and with a mobility having a normal value. A nuclear-spin polarization device 1 creates a state where the Landau-level separation and the Zeeman-level separation in a sample are equal to each other in a magnetic field, thereby crossing different spin states, and detects nuclear-spin polarization from a resistance change at the crossing point caused by the nuclear-spin polarization.
    Type: Application
    Filed: December 14, 2010
    Publication date: October 11, 2012
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Hongwu Liu, Kaifeng Yang, Yoshiro Hirayama