Patents by Inventor Hongwu TANG

Hongwu TANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIARYL MONOBACTAM COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20200361928
    Abstract: The present invention relates to biaryl monobactam compounds of Formula I and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A1, Q, A2, M, W, RX and Rz are as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.
    Type: Application
    Filed: June 25, 2020
    Publication date: November 19, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Haifeng Tang, Weiguo Liu, Fa-Xiang Ding, Wanying Sun, Yi Zang, Weidong Pan, Anthony Ogawa, Linda Brockunier, Xianhai Huang, Hongwu Wang, Rudrajit Mal, Tesfaye Biftu, Min Park, Yan Guo, Jinlong Jiang, Helen Y. Chen, Christopher W. Plummer
  • Device for measuring adsorption/desorption characteristic of surface bed sediments on contaminants and method of using the device
    Patent number: 10545128
    Abstract: The present invention discloses a device for measuring adsorption/desorption of contaminants onto surface bed sediments and a method of using the device. The measurement device includes a sediment sample disc, a sample holder, a reaction cylinder, a liquid collection cylinder, and a liquid circulating member from inside to outside, the liquid circulating member consisting of rubber pipes and a peristaltic pump.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: January 28, 2020
    Assignee: Hohai University
    Inventors: Hongwu Tang, Qingxia Li, Yang Xiao, Zhiwei Li, Saiyu Yuan
  • Bicyclic aryl monobactam compounds and methods of use thereof for the treatment of bacterial infections
    Patent number: 10407421
    Abstract: The present invention relates to bicyclic aryl monobactam compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein A1, L, M, W, X, Y, Z, RX and Rz are as defined herein. The present invention also relates to compositions which comprise a bicyclic aryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of one or more beta-lactamase inhibitor compounds.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: September 10, 2019
    Assignee: Merck Sharp & Dohme Corp
    Inventors: Weiguo Liu, Fa-Xiang Ding, Wanying Sun, Reynalda Keh Dejesus, Haifeng Tang, Xianhai Huang, Jinlong Jiang, Yan Guo, Hongwu Wang
  • DEVICE FOR MEASURING ADSORPTION/DESORPTION CHARACTERISTIC OF SURFACE BED SEDIMENTS ON CONTAMINANTS AND METHOD OF USING THE DEVICE
    Publication number: 20190212318
    Abstract: The present invention discloses a device for measuring adsorption/desorption of contaminants onto surface bed sediments and a method of using the device. The measurement device includes a sediment sample disc, a sample holder, a reaction cylinder, a liquid collection cylinder, and a liquid circulating member from inside to outside, the liquid circulating member consisting of rubber pipes and a peristaltic pump.
    Type: Application
    Filed: October 10, 2017
    Publication date: July 11, 2019
    Applicant: Hohai University
    Inventors: Hongwu TANG, Qingxia LI, Yang XIAO, Zhiwei LI, Saiyu YUAN