Patents by Inventor Hongyan Zhong

Hongyan Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CARDIOVASCULAR DISEASES
    Publication number: 20180155447
    Abstract: Provided herein are methods that relate to a novel therapeutic strategy for treatment of heart and/or cardiovascular diseases. The method includes administration of LOXL2 inhibitors for treating, preventing, or ameliorating at least one symptom associated with heart and/or cardiovascular diseases.
    Type: Application
    Filed: October 19, 2017
    Publication date: June 7, 2018
    Inventors: Peidong Fan, Jong Kang, Amanda Mikels-Vigdal, Lina Yao, Hongyan Zhong
  • METHODS FOR TREATING CARDIOVASCULAR DISEASES
    Publication number: 20150361182
    Abstract: Provided herein are methods that relate to a novel therapeutic strategy for treatment of heart and/or cardiovascular diseases. The method includes administration of LOXL2 inhibitors for treating, preventing, or ameliorating at least one symptom associated with heart and/or cardiovascular diseases.
    Type: Application
    Filed: June 4, 2015
    Publication date: December 17, 2015
    Inventors: Peidong Fan, Jong Kang, Amanda Mikels-Vigdal, Lina Yao, Hongyan Zhong
  • METHOD OF PREVENTING AND TREATING HEPATIC DISEASE USING A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20140243358
    Abstract: The invention is related to methods of preventing and treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Application
    Filed: October 4, 2013
    Publication date: August 28, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • Method of inhibiting hepatic fibrosis as a result of liver replacement or repair using Aadenosine receptor antagonists
    Patent number: 8609671
    Abstract: The invention is related to methods of inhibiting hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: December 17, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • USE OF A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING HEART FAILURE AND ARRHYTHMIA IN POST-MYOCARDIAL INFARCTION PATIENTS
    Publication number: 20120258974
    Abstract: Provided are methods of improving the cardiac condition of post-myocardial infarction (MI) patients and reducing cardiovascular death and hospitalization due to heart failure or arrhythmias, by administering a therapeutically effective amount of an A2B adenosine receptor antagonist.
    Type: Application
    Filed: April 5, 2012
    Publication date: October 11, 2012
    Inventors: Luiz Belardinelli, Hongyan Zhong, Dewan Zeng
  • METHOD OF PREVENTING AND TREATING HEPATIC DISEASE USING A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20120220608
    Abstract: The invention is related to methods of preventing and treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Application
    Filed: February 28, 2012
    Publication date: August 30, 2012
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • Method of decreasing hepatotoxic side effects using Aadenosine receptor antagonists
    Patent number: 8188099
    Abstract: The invention is related to a method of decreasing hepatotoxic side effects using an A2B adenosine receptor antagonist and utility in the treatment of liver damage caused by undergoing hepatotoxic treatment, such as chemotherapy or radiation. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: May 29, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • Use of A2B Adenosine Receptor Antagonists for Treating Pulmonary Hypertension
    Publication number: 20120003329
    Abstract: This disclosure relates generally to treating patients having pulmonary hypertension, or symptoms associated therewith, by administering a therapeutically effective amount of an A2B receptor antagonist to the patient.
    Type: Application
    Filed: June 29, 2011
    Publication date: January 5, 2012
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • METHOD OF TREATING HEPATIC DISEASE USING A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20110184002
    Abstract: The invention is related to methods of preventing and treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Application
    Filed: August 10, 2010
    Publication date: July 28, 2011
    Applicant: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Dewan Zeng, Hongyan Zhong
  • Method of treating hepatic disease using Aadenosine receptor antagonists
    Patent number: 7795268
    Abstract: The invention is related to methods of treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: September 14, 2010
    Assignee: Gilead Palo Alto, Inc.
    Inventors: Dewan Zeng, Hongyan Zhong, Luiz Belardinelli
  • A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20080318983
    Abstract: Disclosed are methods for treating asthma, inflammatory gastrointestinal tract disorders, cancer, cardiovascular diseases, neurological disorders, and diseases related to undesirable angiogenesis using A2B adenosine receptor antagonists having the structure of Formula I or Formula II:
    Type: Application
    Filed: June 26, 2008
    Publication date: December 25, 2008
    Inventors: Rao Kalla, Thao Perry, Elfatih Elzein, Vaibhav Varkhedkar, Xiaofen Li, Prabha Ibrahim, Venkata Palle, Dengming Xiao, Jeff Zablocki, Dewan Zeng, Hongyan Zhong
  • A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20080194593
    Abstract: Disclosed are methods for treating asthma, inflammatory gastrointestinal tract disorders, cancer, cardiovascular diseases, neurological disorders, and diseases related to undesirable angiogenesis using A2B adenosine receptor antagonists having the structure of Formula I or Formula II:
    Type: Application
    Filed: January 11, 2008
    Publication date: August 14, 2008
    Inventors: Rao Kalla, Thao Perry, Elfatih Elzein, Xiaofen Li, Jeff Zablocki, Dewan Zeng, Dengming Xiao, Vaibhav Varkhedkar, Prabha Ibrahim, Venkata Palle, Hongyan Zhong
  • METHOD OF PREVENTING AND TREATING HEPATIC DISEASE USING A2B ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20070219221
    Abstract: The invention is related to methods of preventing and treating hepatic fibrosis using A2B adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method.
    Type: Application
    Filed: March 16, 2007
    Publication date: September 20, 2007
    Inventors: Dewan Zeng, Hongyan Zhong, Luiz Belardinelli