Patents by Inventor Hongyi Yu

Hongyi Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolopyrimidine derivatives as PI3 kinase inhibitors
    Patent number: 9096605
    Abstract: PI3K? selective compounds having the structure
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: August 4, 2015
    Assignee: GlaxoSmithKline LLC
    Inventors: Hong Lin, Juan Ignacio Luengo, Michael Lee Moore, Junya Qu, Ralph A. Rivero, Rosanna Tedesco, Hongyi Yu
  • Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors
    Publication number: 20140187545
    Abstract: PI3K? selective compounds having the structure
    Type: Application
    Filed: June 29, 2012
    Publication date: July 3, 2014
    Applicant: GlaxoSmithKline LLC
    Inventors: Hong Lin, Juan Luengo, Michael Lee Moore, Junya Qu, Ralph A. Rivero, Rosanna Tedesco, Hongyi Yu
  • IL-8 receptor antagonists
    Patent number: 8044075
    Abstract: This invention relates to novel compounds, compositions and combinations thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: October 25, 2011
    Assignee: GlaxoSmithKline
    Inventors: Gregory L. Adams, James A. Brackley, III, Jakob Busch-Petersen, Jianghe Deng, Wei Fu, Huijie Li, Jack J. Taggart, Feng Wang, Yonghui Wang, Katherine Louisa Widdowson, Hongyi Yu
  • PROLYL HYDROXYLASE INHIBITORS
    Publication number: 20110098324
    Abstract: The invention described herein relates to certain pyrimidinedione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
    Type: Application
    Filed: June 23, 2009
    Publication date: April 28, 2011
    Inventors: James A. Brackley, III, Antony Nicholas Shaw, Rosanna Tedesco, Yonghui Wang, Kenneth J. Wiggall, Hongyi Yu
  • PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME
    Publication number: 20080039455
    Abstract: The invention relates to pyrazolopyrimidines according to the general formula (I): and salts thereof, to pharmaceutical compositions comprising said pyrazolopyrimidines and to a method of preparing said pyrazolopyrimidines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment or prophylaxis of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth
    Type: Application
    Filed: June 20, 2007
    Publication date: February 14, 2008
    Inventors: Stuart Ince, Olaf Prien, Shoufu Lu, Hongyi Yu, Manfred Husemann, Karina Schuck
  • Indolinone derivatives and their use in treating disease-states such as cancer
    Patent number: 7105563
    Abstract: Indolinone derivatives, such as compounds of the formula (I): wherein A, m, n, R1, R2, R3, R5 and R6 are described herein, are disclosed herein as being useful in treating mammal having disease-states alleviated by the inhibition of PDK-1 activity.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: September 12, 2006
    Assignee: Schering Aktiengesellschaft
    Inventors: Damian Arnaiz, Judi Bryant, Yuo-Ling Chou, Richard Feldman, Paul Hrvatin, Imadul Islam, Monica Kochanny, Wheeseong Lee, Mark Polokoff, Hongyi Yu, Shendong Yuan
  • Piperidine derivatives and their use as anti-inflammatory agents
    Publication number: 20060167044
    Abstract: Piperidine derivatives of the following formulae I and II: and their pharmaceutically acceptable salts, which are functional antagonists of the CC chemokine receptor CCR1 and are thus useful as anti-inflammatory agents, a pharmaceutical compositions containing said piperidine derivatives or their pharmaceutically acceptable salts, and methods of their use.
    Type: Application
    Filed: December 19, 2005
    Publication date: July 27, 2006
    Inventors: Damian Arnaiz, Yuo-Ling Chou, Monica Kochanny, Wheeseong Lee, Shou-Fu Lu, Anne Mengel, Gary Phillips, Guo Wei, Hongyi Yu
  • Indolinone derivatives and their use in treating disease-states such as cancer
    Publication number: 20050090541
    Abstract: Indolinone derivatives, such as compounds of the formula (I): wherein A, m, n, R1, R2, R3, R5 and R6 are described herein, are disclosed herein as being useful in treating mammal having disease-states alleviated by the inhibition of PDK-1 activity.
    Type: Application
    Filed: October 22, 2004
    Publication date: April 28, 2005
    Applicant: Schering Aktiengesellschaft
    Inventors: Damian Arnaiz, Judi Bryant, Yuo-Ling Chou, Richard Feldman, Paul Hrvatin, Imadul Islam, Monica Kochanny, Wheeseong Lee, Mark Polokoff, Hongyi Yu, Shendong Yuan