Patents by Inventor Hongying HUANG
Hongying HUANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240066112Abstract: Provided is a GII.4 norovirus virus-like particle or active fragment thereof, and use thereof, the virus-like particle comprising or being composed of an amino acid sequence shown as SEQ ID NO: 4. Further, provided is a composition or a kit comprising the GII.4 norovirus virus-like particle, and use thereof. The objective of covering multiple genotypes is achieved by using a single antigen of the invention, the process difficulty of the preparation for a pharmaceutical composition or a vaccine can be reduced, and the production cost is decreased. Also, provided is a norovirus immune composition or a kit comprising GII.2, GII.4, GII.6, and GII.17 norovirus virus-like particles or active fragments thereof, and use thereof.Type: ApplicationFiled: December 21, 2021Publication date: February 29, 2024Applicant: GRAND THERAVAC LIFE SCIENCE (NANJING) CO., LTD.Inventors: Jianqiang Li, Jun Ge, Xiaodong Wang, Changyao Tan, Sulin Ren, Tong Zhou, Yue Gu, Yue Chen, Hongying Huang, Xiaoxiao Chen
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Patent number: 11633714Abstract: A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water.Type: GrantFiled: November 26, 2018Date of Patent: April 25, 2023Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCESInventors: Enhui Sun, Hongying Huang, Hongmei Jin, Guofeng Wu, Zhizhou Chang, Xiaomei Ye, Yueding Xu, Cheng Yong
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Publication number: 20230073321Abstract: The present invention belongs to the field of biopharmaceutics and in particular relates to a pharmaceutical composition. The pharmaceutical composition comprises a hepatitis B surface antigen, a hepatitis B core antigen, and an immunostimulatory composition, wherein the immunostimulatory composition comprises a saponin and a CpG oligodeoxynucleotide, or consists of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide.Type: ApplicationFiled: December 11, 2020Publication date: March 9, 2023Applicant: GRAND THERAVAC LIFE SCIENCE (NANJING) CO., LTD.Inventors: Jianqiang Li, Jun Ge, Jiaojiao Sun, Tong Zhou, Sulin Ren, Changyao Tan, Yue Gu, Hongying Huang, Shiwei Wang, Xiaoxiao Chen, Jingfeng Huang, Xaiodong Wang, Yue Chen
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Publication number: 20230040021Abstract: Provided is an immunostimulatory composition, comprising a saponin and a CpG oligodeoxynucleotide, or consisting of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide, wherein the sequence of the CpG oligodeoxynucleotide has two or more copies of 5?-TTCGTT-3? motif or 5?-TCGTCGTCG-3? motif. Also provided is use of the immunostimulatory composition in the preparation of a medication for treating diseases.Type: ApplicationFiled: December 11, 2020Publication date: February 9, 2023Applicant: GRAND THERAVAC LIFE SCIENCE (NANJING) CO., LTD.Inventors: Jun Ge, Jianqiang Li, Jiaojiao Sun, Tong Zhou, Sulin Ren, Yue Gu, Hongying Huang, Shiwei Wang, Jingfeng Huang
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Publication number: 20220088188Abstract: The present invention discloses a pharmaceutical preparation for treating hepatitis B, a preparation method and use thereof. The pharmaceutical preparation comprises a solution of hepatitis B surface antigen, further a solution of hepatitis B core antigen, and furthermore an oligodeoxynucleotide solution. The pharmaceutical preparation is free of saccharide, has a simple composition and a good antigen stability, without the adverse reactions caused by aluminum adjuvants, and shows good preservation effects in long-term stability experiments.Type: ApplicationFiled: November 15, 2019Publication date: March 24, 2022Applicant: GRAND THERAVAC LIFE SCIENCE (NANJING) CO., LTD.Inventors: Jianqiang Li, Jun Ge, Sulin Ren, Hongying Huang, Jiaojiao Sun, Honglin Sun, Tong Zhou, Yue Gu, Xiaoxiao Chen, Xue Zhou
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Malic acid and KMnO-based combined and modified cow dung biogas residue hydrochar preparation method
Patent number: 11235305Abstract: A malic acid and KMnO4-based combined and modified cow dung biogas residue hydrochar preparation method, comprising: mixing a cow dung biogas residue with malic acid, and performing ultrasonic treatment to obtain a malic acid modified cow dung biogas residue; performing a hydrothermal reaction with KMnO4 in a high-temperature high-pressure reactor to obtain a combined and modified cow dung biogas residue hydrochar material.Type: GrantFiled: July 2, 2018Date of Patent: February 1, 2022Inventors: Hongmei Jin, Ning Zhu, Yonglan Xi, Enhui Sun, Jing Du, Hongying Huang, Xiaomei Ye, Mengjie Zheng, Danyang Li -
Publication number: 20210274727Abstract: A straw-based pot body blanket seedling growth substrate using straw fibres as a framework, utilising an enhancer, a retention aid and a wet strength agent as additives, and being prepared from composite decomposed livestock manure, perlite and vermiculite, the addition amount of the straw fibres being 60-70 v/v %, the addition amount of the decomposed livestock manure being 5-10 v/v %, the addition amount of the perlite being 5-10 v/v %, the addition amount of the vermiculite being 5-10 v/v %. The pot body blanket seedling growth substrate is suitable for cutting and easily implementing fully automated transplantation, is beneficial for root growth, shortens seeding growth periods, and increases seedling growth bed emergence rates. The pot body blanket seedling growth substrate may be applied to solanaceae seedling growth, and can also provide a block-shaped substrate for landscape flowers and plants in a three-dimensional arrangements.Type: ApplicationFiled: November 7, 2018Publication date: September 9, 2021Inventors: Ping QU, Hongying HUANG, Enhui SUN, Yun CAO, Huashan WU, Yueding XU
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Patent number: 11104648Abstract: A pyrazole derivative having the following formula stru-1: The pyrazole derivative is used for prevention and control of pests.Type: GrantFiled: May 22, 2018Date of Patent: August 31, 2021Assignees: ZHEJIANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD., SINOCHEM LANTIAN CO., LTD.Inventors: Tianming Xu, Jiahua Xing, Liangkun Zhong, Dongsong Hu, Youchang Wei, Hongying Huang, Jiping Yu, Weili Peng
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Publication number: 20200339515Abstract: A pyrazole derivative having the following formula stru-1: The pyrazole derivative is used for prevention and control of pests.Type: ApplicationFiled: May 22, 2018Publication date: October 29, 2020Inventors: Tianming XU, Jiahua XING, Liangkun ZHONG, Dongsong HU, Youchang WEI, Hongying HUANG, Jiping YU, Weili PENG
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Publication number: 20200298202Abstract: A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water.Type: ApplicationFiled: November 26, 2018Publication date: September 24, 2020Inventors: Enhui SUN, Hongying HUANG, Hongmei JIN, Guofeng WU, Zhizhou CHANG, Xiaomei YE, Yueding XU, Cheng YONG
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Publication number: 20200038834Abstract: A malic acid and KMnO4-based combined and modified cow dung biogas residue hydrochar preparation method, comprising: mixing a cow dung biogas residue with malic acid, and performing ultrasonic treatment to obtain a malic acid modified cow dung biogas residue; performing a hydrothermal reaction with KMnO4 in a high-temperature high-pressure reactor to obtain a combined and modified cow dung biogas residue hydrochar material.Type: ApplicationFiled: July 2, 2018Publication date: February 6, 2020Inventors: Hongmei JIN, Ning ZHU, Yonglan XI, Enhui SUN, Jing DU, Hongying HUANG, Xiaomei YE, Mengjie ZHENG, Danyang LI
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Patent number: 9878035Abstract: Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5?-NTCGTT-3? motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.Type: GrantFiled: February 26, 2014Date of Patent: January 30, 2018Assignee: JIANGSU THERAVAC BIO-PHARMACEUTICAL CO., LTD.Inventors: Sean Xiaohan Du, Jun Ge, Xiaoqian Zhuang, Tong Zhou, Jianqiang Li, Cuiling Song, Ying Sun, Meiju Wang, Yue Gu, Honglin Sun, Zhenxing Xu, Hongying Huang, Xiaoxiao Chen
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Publication number: 20160136264Abstract: Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5?-NTCGTT-3? motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.Type: ApplicationFiled: February 26, 2014Publication date: May 19, 2016Applicant: JIANGSU THERAVAC BIO-PHARMACEUTICAL CO., LTD.Inventors: Sean Xiaohan DU, Jun GE, Xiaoqian ZHUANG, Tong ZHOU, Jianqiang LI, Cuiling SONG, Ying SUN, Meiju WANG, Yue GU, Honglin SUN, Zhenxing XU, Hongying HUANG, Xiaoxiao CHEN