Patents by Inventor HongYing Wang
HongYing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250082827Abstract: The invention relates to a double-microenvironment three-layer bionic hydrogel scaffold and a preparation method and application thereof, which are characterized in that includes a cartilage layer GL-HPKGN, an intermediate layer GL-GMA, and a bone layer GL-HP/GMAAT; by an enzymatic crosslinking reaction based on hydroxyphenylpropionic acid (HPA), kartogenin (KGN) is grafted onto gelatin to form a cartilage-specific microenvironment in GL-HPKGN; Based on hydroxyphenylpropionic acid (HPA), a dual crosslinking network was formed by enzyme crosslinking reaction and methacryloyl-glycidyl dimethicone (GMA) photo-crosslinking reaction, which was used to graft atorvastatin (AT) onto gelatin, forming GL-HP/GMAAT with bone-specific microenvironment; the intermediate layer GL-GMA was beneficial for forming a clear and defined cartilage-bone integrated structure. The introduction of the tide-line intermediate layer GL-GMA facilitated the formation of well-defined chondro-bone integrated structures.Type: ApplicationFiled: November 25, 2024Publication date: March 13, 2025Inventors: Yongkun Sun, Wenjie Ren, Zhengnan Zhang, Guangdong Zhou, Xianwei Wang, Xiaomeng Li, Yujie Hua, Shuhong Zhang, Zhikun Guo, Hongying Chen, Weiwei Zhao, Huanhuan Li, Zihan Zhao
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Publication number: 20250031643Abstract: The present application discloses a semi-dominant molecular marker related to maize dwarf and an application thereof, and relates to the technical field of maize molecular breeding. The molecular marker related to the maize dwarf is caused by a non-synonymous mutation from G to A in a maize gene Zm00001d013465, and the molecular marker is a nucleotide sequence composed of the non-synonymous mutation site and its upstream and downstream bases. The present application identifies a dwarf mutant, coded as E5779, from an EMS mutation population with maize B73 as the genetic background. By genome resequencing and Mutmap mapping, it is found that the mutant is caused by the non-synonymous mutation from G to A in the gene Zm00001d013465. The molecular marker is developed based on this, and the analysis and utilization of E5779 are helpful to improve the maize plant height and density-tolerant breeding, it has an important breeding application potential.Type: ApplicationFiled: October 10, 2024Publication date: January 30, 2025Applicants: ANHUI AGRICULTURAL UNIVERSITY, CHINA NATIONAL SEED GROUP CO., LTD.Inventors: Yang ZHAO, Qing MA, Xiaoduo LU, Yixiao WANG, Hongying WU
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Publication number: 20250029479Abstract: The present invention discloses a method and a system for improving the alarm reliability of a smoke fire detector. The method comprises the following steps: S1, Set an updated background threshold, an alarm threshold and an aerosol type threshold. S2, Initialize the background value of the smoke detector. S3, Regularly update the detection value. S4, Regularly update the long-period background value. S5, Update the short-period background value according to the threshold method. S6, Identify the aerosol type. S7, Give an alarm of fire smoke alarm. S8, Give an alarm of interfering substances.Type: ApplicationFiled: June 4, 2024Publication date: January 23, 2025Applicant: BENGBU EI FIRE ELECTRONICS CO., LTD.Inventors: Hongying ZHANG, Zhenfei HAN, Jianjun WANG, Guangbiao ZHANG, Chao JI, Hongchi MA, Shuai HAO
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Publication number: 20240309273Abstract: A surfactant composition includes 60 wt % or greater of a surfactant based on a total weight of the surfactant composition. 0.01 wt % to 1 wt % of an antioxidant, and 0.01 wt % to 5 wt % of a hydroxyl amine having structure (I) based on the total weight of the surfactant composition wherein R1, R2 and R3 of Structure (I) are independently selected from the group consisting of H, an alkanolamine, or a hydroxyl alkyl group with linear or branched carbon chain having from 1 to 8 carbons, and R4 of Structure (I) is selected from the group consisting of an alkanolamine, or a hydroxyl alkyl group with linear or branched carbon chain having from 1 to 8 carbons.Type: ApplicationFiled: October 6, 2021Publication date: September 19, 2024Inventors: Qianyuan Shan, Cheng Shen, Jian Zou, Zhouhua Ji, Shuyu Duan, Hongying Wang
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Publication number: 20230416181Abstract: An odor removal composition for oxygenated solvents comprising an alcohol amine.Type: ApplicationFiled: December 18, 2020Publication date: December 28, 2023Inventors: Cheng Shen, Jian Zou, Shuyu Duan, Hongying Wang, Jing Ji
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Publication number: 20230346896Abstract: Provided is a method for preparing a polyethylene glycol-modified urate oxidase, at least 11 of the following amino acid sites of the polyethylene glycol-modified urate oxidase have a PEG modification: T1, K3, K4, K30, K35, K76, K79, K97, K112, K116, K120, K152, K179, K222, K231, K266, K272, K285, K291, and K293, and the preparation method includes: performing a coupling reaction between urate oxidase and polyethylene glycol, wherein the polyethylene glycol is provided in the form of an acidic solution, and a molar ratio of the urate oxidase to the polyethylene glycol is 1: (56 to 94), to obtain the polyethylene glycol-modified urate oxidase.Type: ApplicationFiled: May 4, 2023Publication date: November 2, 2023Applicant: HANGZHOU GRAND BIOLOGIC PHARMACEUTICAL INC.Inventors: RIYONG LIU, Zhiming WANG, Yunfeng HE, Yu WANG, Zhicheng FU, Tianwen YAN, Chunlan HU, Guowei SU, Changcheng TAN, Xupeng DING, Hui YANG, Hongying WANG, Qiong DING, Qian WANG, Haiyan WEN, Kai FAN
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Publication number: 20230346959Abstract: Provided is a urate oxidase preparation. The urate oxidase preparation includes polyethylene glycol-modified urate oxidase as an active ingredient and a buffer reagent as an excipient.Type: ApplicationFiled: May 4, 2023Publication date: November 2, 2023Applicant: HANGZHOU GRAND BIOLOGIC PHARMACEUTICAL INC.Inventors: Yunfeng HE, Zhiming WANG, Zhicheng FU, Yu WANG, Haiyan WEN, Tianwen YAN, Chunlan HU, Guowei SU, Riyong LIU, Xupeng DING, Kai FAN, Hongying WANG, Qian WANG
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Publication number: 20230075575Abstract: Provided is an aqueous coating composition comprising a binder and a coalescent which is based on a secondary alcohol alkoxylate or a tertiary alcohol alkoxylate.Type: ApplicationFiled: March 31, 2020Publication date: March 9, 2023Inventors: Cheng Shen, Yan Li, Jian Zou, Shaoguang Feng, Hongying Wang
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Patent number: 11522556Abstract: In certain aspects, an analog-to-digital converter (ADC) includes a comparator having a first input, a second input, and an output. The ADC also includes a digital-to-analog converter (DAC) coupled to the first input of the comparator, a switching circuit, a first capacitor coupled between the first input of the comparator and the switching circuit, a second capacitor coupled between the first input of the comparator and the switching circuit, and an amplifying circuit having an input and an output, wherein the input of the amplifying circuit is coupled to the switching circuit. The ADC further includes a first switch coupled between the output of the amplifying circuit and the DAC, and a successive approximation register (SAR) having an input and an output, wherein the input of the SAR is coupled to the output of the comparator, and the output of the SAR is coupled to the DAC.Type: GrantFiled: July 26, 2021Date of Patent: December 6, 2022Assignee: QUALCOMM INCORPORATEDInventors: Behzad Sheikholeslami, Marceline Kelly Tchambake Yapti, Prateek Tripathi, Hongying Wang
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Patent number: 11401560Abstract: Disclosed are a set of genes for bladder cancer detection and their use. The set of genes includes the following 32 genes: CA9 gene, CDK1 gene, CTSE gene, DMBT1 gene, ERBB2 gene, HOXA13 gene, IGF2 gene, CXCR2 gene, MAGEA3 gene, MDK gene, MMP1 gene, MMP12 gene, RBP2 gene, CCL18 gene, SNAI2 gene, VEGFA gene, MFAP5 gene, SGK2 gene, WFDC2 gene, POSTN gene, NPFFR2 gene, ANXA10 gene, CTAG2 gene, ZDHHC2 gene, KRT20 gene, PPP1R14D gene, FGD3 gene, AHNAK2 gene, SEMA3D gene, ZNF707 gene, LOC100652931 gene, and LINC00565 gene. After clinical validation, the kit provided by the present invention is used to detect bladder cancer with a high accuracy rate and objective interpretation of results. Meanwhile, as a non-invasive detection, the compliance of patients is greatly improved comparing with the existing cystoscopy, which has an important clinical significance for the early detection and postoperative monitoring of bladder cancer.Type: GrantFiled: January 17, 2019Date of Patent: August 2, 2022Assignee: HANGZHOU CANHELP GENOMICS TECHNOLOGY CO. LTD.Inventors: Qinghua Xu, Dingwei Ye, Qifeng Wang, Chengshu Chen, Jinying Chen, Yifeng Sun, Wanli Ren, Hongying Wang, Yiwang Wu, Tao Huo
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Publication number: 20220054598Abstract: The present disclosure provides a polyethylene glycol-modified urate oxidase. At least 11 of the following amino acid sites in the urate oxidase have a PEG modification: T1, K3, K4, K30, K35, K76, K79, K97, K112, K116, K120, K152, K179, K222, K231, K266, K272, K285, K291, and K293.Type: ApplicationFiled: November 9, 2021Publication date: February 24, 2022Inventors: Kai FAN, Zhiming WANG, Riyong LIU, Yu WANG, Yunfeng HE, Tianwen YAN, Zhicheng FU, Guowei SU, Chunlan HU, Xupeng DING, Changcheng TAN, Hongying WANG, Hui YANG, Qiong DING, Haiyan WEN
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Patent number: 11221921Abstract: Embodiments of the present disclosure relate to a method, electronic device and computer readable storage medium for data backup and recovery. The data backup method comprises: receiving data to be backed up and metadata describing the data to be backed up, the data to be backed up comprising a file and a directory, the metadata comprising file data associated with the file and directory data associated with the directory; generating path data associated with both the file and the directory based on the file data and the directory data; and storing the file data, the directory data, and the path data in association with the data to be backed up.Type: GrantFiled: February 25, 2019Date of Patent: January 11, 2022Assignee: EMC IP HOLDING COMPANY LLCInventors: Jimmy Zhang, Hong Deng, Sammi Hongying Wang
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Publication number: 20210396138Abstract: The present invention discloses a self-anchored opposite-pulling anti-impact anchor cable for sectional coal pillars and a using method thereof. The anchor cable includes a steel strand (100), with an energy-absorbing and yielding terminal (200) and a stressed expansion-cracking terminal (300) respectively fixed to two ends of the steel strand, a bushing (400) sleeved outside the steel strand, a first lock (610) provided at one end of the steel strand and a second lock (620) provided at the other end of the steel strand; the stressed expansion-cracking terminal includes a self-anchored bushing (420) with a plurality of pre-splitting lines (440) arranged in the wall of the self-anchored bushing. Under stress, the wall of the self-anchored bushing cracks along the pre-splitting lines and bends and expands, so that it abuts against and is self-anchored to the edge of a sectional coal pillar at the outer side.Type: ApplicationFiled: October 16, 2020Publication date: December 23, 2021Applicants: LIAONING UNIVERSITY, Beijing Chengtian Hengye Coal Mine Equipment Co. LtdInventors: Yishan Pan, Hongying Wang, Lianpeng Dai, Aiwen Wang, Zhicai Chen, Yonghui Xiao
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Publication number: 20210376844Abstract: A novel and useful digitally intensive event-driven quasi-level crossing (quasi-LC) delta modulator analog to digital converter (ADC) with adaptive resolution (AR) for Internet of Things (IoT) wireless networks. Minimizing the average sampling rate for sparse input signals significantly reduces the power consumed in data transmission, processing, and storage. The AR quasi-LC delta modulator quantizes the residue voltage signal with a 4-bit asynchronous successive approximation register (SAR) sub-ADC, which enables a straightforward implementation of LC and AR algorithms in the digital domain. The modulator achieves data compression by means of a globally signal dependent average sampling rate and achieves AR through a digital multilevel comparison window that overcomes the tradeoff between the dynamic range and the input bandwidth in conventional LC ADCs. Engaging the AR algorithm reduces the average sampling rate by a factor of three at the edge of the modulator's signal bandwidth.Type: ApplicationFiled: June 1, 2021Publication date: December 2, 2021Inventors: Hongying Wang, Filippo Schembari, Robert Bogdan Staszewski
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Patent number: 11187081Abstract: The present invention discloses a self-anchored opposite-pulling anti-impact anchor cable for sectional coal pillars and a using method thereof. The anchor cable includes a steel strand (100), with an energy-absorbing and yielding terminal (200) and a stressed expansion-cracking terminal (300) respectively fixed to two ends of the steel strand, a bushing (400) sleeved outside the steel strand, a first lock (610) provided at one end of the steel strand and a second lock (620) provided at the other end of the steel strand; the stressed expansion-cracking terminal includes a self-anchored bushing (420) with a plurality of pre-splitting lines (440) arranged in the wall of the self-anchored bushing. Under stress, the wall of the self-anchored bushing cracks along the pre-splitting lines and bends and expands, so that it abuts against and is self-anchored to the edge of a sectional coal pillar at the outer side.Type: GrantFiled: October 16, 2020Date of Patent: November 30, 2021Assignees: LIAONING UNIVERSITY, BEIJING CHENGTIAN HENGYE COAL MINE EQUIPMENT CO. LTDInventors: Yishan Pan, Hongying Wang, Lianpeng Dai, Aiwen Wang, Zhicai Chen, Yonghui Xiao
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Publication number: 20210180140Abstract: Disclosed are a set of genes for bladder cancer detection and their use. The set of genes includes the following 32 genes: CA9 gene, CDK1 gene, CTSE gene. DMBT1 gene, ERBB2 gene, HOXA13 gene, IGF2 gene, CXCR2 gene, MAGEA3 gene, MDK gene, MMP1 gene, MMP12 gene, RBP2 gene, CCL18 gene, SNAI2 gene, VEGFA gene, MFAP5 gene, SGK2 gene, WFDC2 gene, POSTN gene, NPFFR2 gene, ANXA10 gene, CTAG2 gene, ZDHHC2 gene, KRT20 gene, PPP1R14D gene, FGD3 gene, AHNAK2 gene, SEMA3D gene, ZNF707 gene, LOC100652931 gene, and LINC00565 gene. After clinical validation, the kit provided by the present invention is used to detect bladder cancer with a high accuracy rate and objective interpretation of results. Meanwhile, as a non-invasive detection, the compliance of patients is greatly improved comparing with the existing cystoscopy, which has an important clinical significance for the early detection and postoperative monitoring of bladder cancer.Type: ApplicationFiled: January 17, 2019Publication date: June 17, 2021Applicant: HANGZHOU CANHELP GENOMICS TECHNOLOGY CO. LTD.Inventors: Qinghua XU, Qifeng WANG, Chengshu CHEN, Jinying CHEN, Yifeng SUN, Wanli REN, Hongying WANG, Yiwang WU, Tao HUO
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Patent number: 10774642Abstract: A hydraulic support unit and a hydraulic support for anti-rock burst roadway. The hydraulic support unit includes a base, a top beam, and a hydraulic support column, the top beam is positioned above the base in a spaced manner; the hydraulic support column are disposed between the base and the top beam; a side guard plate and a first base hydraulic cylinder are disposed on the left side and right side of the base, the side guard plates are rotably connected to the base, the two ends of the first base hydraulic cylinder are hinged to the base and the side guard plate respectively, the first base hydraulic cylinder can drive the side guard plate to transit between a horizontal state and a vertical state, and the bottom surfaces of the side guard plates are flush with the bottom surface of the base in the horizontal state.Type: GrantFiled: June 3, 2019Date of Patent: September 15, 2020Assignees: Liaoning University, Beijing Chengtian Hengye Coal Mine Equipment Co. Ltd., Liaoning Technical UniversityInventors: Yishan Pan, Hongying Wang, Zhi Tang, Zhigao Zhang, Hongqi Shi
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Publication number: 20200117543Abstract: Embodiments of the present disclosure relate to a method, electronic device and computer readable storage medium for data backup and recovery. The data backup method comprises: receiving data to be backed up and metadata describing the data to be backed up, the data to be backed up comprising a file and a directory, the metadata comprising file data associated with the file and directory data associated with the directory; generating path data associated with both the file and the directory based on the file data and the directory data; and storing the file data, the directory data, and the path data in association with the data to be backed up.Type: ApplicationFiled: February 25, 2019Publication date: April 16, 2020Inventors: Jimmy Zhang, Hong Deng, Sammi Hongying Wang
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Patent number: 10458155Abstract: A latch for a closure panel of a vehicle including a latch housing; a ratchet mounted to the latch housing and movable between a closed position and an open position, the ratchet having a channel for receiving a striker with a first portion relative to the channel and a second portion relative to the channel, the channel having an over slam region positioned adjacent to a bottom of the channel; a pawl mounted to the latch housing and movable between a ratchet holding position and a ratchet release position; and a pair of levers mounted to the latch housing and configured for corotation about a pivot, the pair of levers biased towards a rest position by a biasing member coupled to at least one of the pair of levers.Type: GrantFiled: December 7, 2016Date of Patent: October 29, 2019Assignee: MAGNA CLOSURES INC.Inventors: Jianjun Yu, Hongying Wang, Hongyuan Li
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Patent number: 9964855Abstract: A method is disclosed that includes forming at least one substrate alignment mark and at least one lithography alignment mark in a substrate; forming a seed layer on the substrate; and forming a guide pattern and at least one guide pattern alignment mark in the seed layer, where the at least one guide pattern alignment mark is formed over the at least one substrate alignment mark. The method further includes determining an alignment error of the at least one guide pattern alignment mark relative to the at least one substrate alignment mark; and patterning features on at least one region of the substrate, where the features are positioned on the substrate based on the at least one lithography alignment mark and the alignment error.Type: GrantFiled: October 10, 2016Date of Patent: May 8, 2018Assignee: Seagate Technology LLCInventors: HongYing Wang, Kim Y. Lee, Yautzong Hsu, Nobuo Kurataka, Gennady Gauzner, Shuaigang Xiao