Abstract: A self-adaptive seat comfort system based on a fitness of occupant and seat, comprising an ECU control system, wherein the ECU control system is provided with a communication module, a microcontroller, a power supply module, a seat-occupant fitness detection module and a comfort adjustment module, where the seat-occupant fitness detection module and the comfort adjustment module are connected bidirectionally with the microcontroller through wires, and the microcontroller module is connected bidirectionally with the communication module through wires. Compared with the prior art, the present invention provides the self-adaptive seat comfort system and the adjustment method based on the fitness of occupant and seat, which can further realize intelligent dynamic adjustment, and adjust the supporting positions for various parts dynamically according to the degree of fitness of occupant and seat detected by the sensing circuit provided on the seat comfort system.