Abstract: The present invention discloses a systematic pharmacological method for personalized medicine. In the present invention, biological networks such as gene dependence networks are employed to reflect relationships between genes in pathogenesis. In combination with the gene expression data of a specific patient, a gene rank algorithm, which is capable of utilizing inter-genetic regulation relationships to mine key genes in the pathogenesis of disease in a specific patient, is used to construct a key genes list. Then, personalized medicine is carried out according to whether the drug targets are significantly targeted to the key genes list in the pathogenesis of disease in the specific patient. The systematic pharmacological method for personalized medicine proposed by the present invention is easy to implement, has low cost and high efficiency, and has wide application prospects in precision medicine and drug discovery.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: A sealant applying device and a working method thereof, and a sealant applying apparatus are disclosed. The sealant applying device includes a nozzle: the nozzle includes an air inlet portion and a sealant outflow portion, a switch plate is arranged below the sealant outflow portion, the switch plate includes a plate body configured to horizontally move between a first state and a second state, one end of the plate body is provided with a through hole, and a discharge portion is provided at a position corresponding to the through hole and on a side of the plate body facing away from the sealant outflow portion.

Abstract: The present invention relates to the field of biomedical technology, and discloses a screening method for multi-target drugs and/or drug combinations. It includes the following steps: step (1): searching a drug target database, summarizing a drug target, a target in development and a drug corresponding to each target, obtaining data of a corresponding relationship between the target and the drug; step (2): screening out a related target-target pair according to a systematic genetics method; step (3): screening out a multi-target drug and/or a drug combination according to the data of the corresponding relationship between the target and the drug obtained in step (1) and the related target-target pair obtained in step (2).

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: A first request is received from a first user to access a first file system management objects (FSMOs) of a first tenant unit (TU), the first TU being one of a plurality of TUs. The first FSMO is one of a plurality of FSMOs, each FSMO containing namespace information of a particular tenant. In response to the first request, it is determined whether the first user is authorized to access the first FSMO, including identifying TUs that are associated with the first user, determining whether the first TU is included in the TUs, and if so, determining whether the first FSMO is included in FSMOs associated with the first TU. In response to determining that the first FSMO is included in a set of one or more FSMOs that are associated with the first TU, the first user to access the first FSMO is allowed.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: A microchannel heat exchanger (100) with improvement of dirt-resisting and anti-blocking is disclosed. The microchannel heat exchanger (100) includes at least two heat exchanger units (101, 102) vertically arranged in parallel with the top one being a first heat exchanger unit (101) and the bottom one being a second heat exchanger unit (102). Every heat exchanger unit (101, 102) includes: a first heat tube (103) and a second heat tube (104) oppositely arranged in the horizontal direction; and multiple flat tubes (105) extending between the first and second heat tubes (103, 104) and having both ends communicated with the first and second heat tubes (103, 104). The microchannel heat exchanger (100) also includes multiple fins (109) each arranged between and in contact with the neighboring flat tubes (105) of the same heat exchanger unit and extending from the first heat exchanger unit (101) to the second heat exchanger unit (102).

Abstract: Exemplary methods for providing secure multi-tenancy in a Purpose Built Backup Appliance include creating a set of tenant-units (TUs), associating file system management objects (FSMOs) and users with the TUs. The methods further include maintaining a protocol config-metadata store based on the association of the FSMOs and users with the TUs. In one embodiment, in response to a first request from a first user to access a first FSMO of a first TU, the methods include determining whether the first user is authorized to access the first FSMO based on information of the protocol config-metadata store, and in response to the protocol config-metadata store indicating the first user is authorized to access the first FSMO, allowing the first user to access the first FSMO.

Abstract: System and methods are provided for processing composite video signals. The system includes: a clock synthesizer configured to generate a line lock clock signal; an interpolation unit configured to generate source data associated with a source composite video signal, the source composite video signal being related to a source clock signal; a buffer unit configured to store the source data based at least in part on the source clock signal and provide destination data based at least in part on the line lock clock signal; a signal processing unit configured to process the destination data to extract a synchronization component and determine a phase error between the synchronization component and the line lock clock signal. The clock synthesizer is further configured to adjust the line lock clock signal based at least in part on the phase error.

Abstract: A native protection storage operating system (PSOS) process receives a request specifying an operation having security related implications for elements in the PSOS having a first set of components handling data transfer operations and a second set of components handling configuration operations. A security component stores an identifier of the requester and a security related information element locally within a storage location of the first or second set of components, and accesses, upon receiving the request, the security related information element and requester identifier to match other elements of the network impacted by the request, and performs a security condition specific check to determine whether or not the request is to be allowed or denied. The native process eliminates a need for caching, locking, and chain propagation of the security related information through the PSOS.

Abstract: Exemplary methods for providing secure multi-tenancy in a Purpose Built Backup Appliance include creating a set of tenant-units (TUs), associating file system management objects (FSMOs) and users with the TUs. The methods further include maintaining a protocol config-metadata store based on the association of the FSMOs and users with the TUs. In one embodiment, in response to a first request from a first user to access a first FSMO of a first TU, the methods include determining whether the first user is authorized to access the first FSMO based on information of the protocol config-metadata store, and in response to the protocol config-metadata store indicating the first user is authorized to access the first FSMO, allowing the first user to access the first FSMO.

Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.

Abstract: Techniques for mining API method usage patterns from source code are described. These techniques include parsing the source code to generate API method call sequences that include an API method. These call sequences are clustered to obtain clusters. Based on the clusters, frequent closed sequences are determined and then clustered to obtain an API usage pattern. In addition, optimal clustering parameters may also be determined. In some instances, a graphical representation is generated based on the API usage pattern in response to a query associated with the API method.

Abstract: The present invention provides a reconfigurable optical add/drop multiplexing device for enabling a totally inresistant colorless, wherein a dropping unit is configured to separate multi-wavelength optical signals which are among direction 1˜X and are broadcast inputted in a circuit direction, switch the multi-wavelength optical signals among the direction 1˜X to any corresponding output port through multiple N×N optical switches, and send the optical signals to a corresponding Receiver (RX) after combining the received optical signals by a corresponding K×1 coupler/optical switch; an adding unit is configured to broadcast the optical signals sent by a Transmitter (TX) to the multiple N×N optical switches through N 1×K couplers/optical switches, switch the optical signals to any corresponding output port by each optical switch, and output the corresponding optical signals in the direction 1˜X to the circuit direction after the optical signals are implemented with optical multiplexing; wherein, X is an integer

Abstract: Techniques for mining API method usage patterns from source code are described. These techniques include parsing the source code to generate API method call sequences that include an API method. These call sequences are clustered to obtain clusters. Based on the clusters, frequent closed sequences are determined and then clustered to obtain an API usage pattern. In addition, optimal clustering parameters may also be determined. In some instances, a graphical representation is generated based on the API usage pattern in response to a query associated with the API method.

Abstract: Processes for catalytically synthesizing ethylbenzene from ethanol and benzene comprising: 1) reacting a first mixture comprising ethanol and benzene with at least one catalyst chosen from binder-containing alkylation catalysts and binder-free alkylation catalysts in an alkylation reactor to obtain a second mixture comprising residual benzene, ethylbenzene, diethylbenzene, and water; 2) passing the second mixture successively through a benzene recovery tower, an ethylbenzene recovery tower, and a polyethylbenzene recovery tower to obtain separated water, separated benzene, separated ethylbenzene, and separated diethylbenzene; and 3) reacting a third mixture with at least one transalkylation catalyst in a transalkylation reactor, wherein the third mixture comprises at least some of the separated benzene and at least some of the separated diethylbenzene at a weight ratio ranging from about 2:1 to about 10:1.

Abstract: An air conditioner system including a condenser fan, an ambient temperature sensor, a refrigerant pressure sensor, and a controller. The ambient temperature sensor is to sense ambient temperature at the system. The refrigerant pressure sensor is to sense pressure of a refrigerant of the system. The target refrigerant pressure module is to identify an optimum pressure of the refrigerant in the system. The controller is to generate an output representing a speed of the condenser fan operable to maintain the pressure of the refrigerant at about the optimum pressure as the ambient temperature of the system changes.

Abstract: An air conditioner system including an indoor unit and an outdoor unit. The outdoor unit includes a condenser, a temperature sensor, a pressure sensor, and a controller. The controller detects a fault with at least one of the temperature sensor or the pressure sensor and adjusts a speed of the condensing fan according to the pressure identified by the pressure sensor when the pressure sensor is operating normally. The controller adjusts the speed of the condensing fan according to the sensed temperature sensor when the pressure experiences a fault and the temperature sensor is operating normally. The controller controls the speed of the condensing fan according to default values when both the pressure sensor and the temperature sensor experience a fault.

Abstract: Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants that are characterized by increased size, have an increased number and size of rosette leaves and are late-flowering.