Patents by Inventor Hongyuan Guo

Hongyuan Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240157437
    Abstract: A method produces tantalum powder. The method includes: (1) uniformly mixing a tantalum powder raw material, metal magnesium and at least one alkali metal and/or alkaline earth metal halide, loading the mixture into a container, and putting the container in a furnace; (2) raising the temperature of the furnace to 600-1200° C. in the presence of inert gas, and soaking; (3) at the end of soaking, lowering the temperature of the furnace to 600-800° C., vacuumizing the interior of the furnace to 10 Pa or less, soaking under the negative pressure so that the excessive metal is separated; (4) thereafter, raising the temperature of the furnace to 750-1200° C. in the presence of inert gas, and soaking so that the tantalum powder is sintered in the molten salt after oxygen reduction; (5) then cooling to room temperature and passivating to obtain a mixed material containing halide and tantalum powder; and (6) separating the tantalum powder from the resulting mixture.
    Type: Application
    Filed: August 24, 2022
    Publication date: May 16, 2024
    Inventors: Yuewei Cheng, Hongyuan Liang, Shun Guo, Jinfeng Zheng, Haiyan Ma, Jingyi Zuo, Li Zhang, Hongjie Qin, Tong Liu, Ying Wang
  • Publication number: 20240150194
    Abstract: A low-carbon, high-purity tantalum pentoxide powder has a carbon content of no greater than 15 ppm. A preparation method for the powder includes: (1) adding a fluotantalic acid (H2TaF7) solution into a reaction kettle, controlling the temperature of the reaction kettle at 30-60° C., adding a precipitator until the pH of the reaction solution is 8-10, then stopping introducing ammonia, and aging to obtain a tantalum hydroxide slurry; (2) filtering and washing the slurry obtained in step (1), and then carrying out solid-liquid separation to obtain a tantalum hydroxide filter cake; (3) drying the filter cake obtained in step (2) to obtain white tantalum hydroxide powder; (4) calcining the tantalum hydroxide powder obtained in step (3), crushing and screening the calcined sample to obtain tantalum pentoxide powder; and (5) subjecting the tantalum pentoxide powder obtained in step (4) to heat treatment at a temperature of 1000-1500° C. to obtain the powder.
    Type: Application
    Filed: August 24, 2022
    Publication date: May 9, 2024
    Applicant: NINGXIA ORIENT TANTALUM INDUSTRY CO., LTD.
    Inventors: Shun Guo, Jinfeng Zheng, Tao Guo, Hongyuan Liang, Yuewei Cheng, Jingyi Zuo, Li Zhang, Ying Wang, Tong Liu, Hongjie Qin
  • Publication number: 20240141361
    Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141344
    Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141347
    Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu ZHANG, Xi CHEN, Zheng FU, Jing LI, Xiang ZHANG, Xinyan ZHOU, Li ZHANG, Mengchao YU, Hongyuan GUO
  • Publication number: 20240141380
    Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Patent number: 11970564
    Abstract: A structural flame retardant high strength low exothermic polymer grouting material for consolidating, belonging to a technical field of polyurethane material, is produced by combined the polyether polyol and the modified isocyanate in a weight ratio of 100:(100-160), leading to internal reaction temperature ?100° C., strength ?60 mPa, bonding ?3 mPa, oxygen index ?28% while no halogen and no effect on water quality, odor level (80° C.) ?3.5, and fog test ?5 mg (which means no physical additive flame retardant is diffused into the environment). In particular, with no halogen, which is known as environmental hormones, in the plasticizers, there will be less combustion smoke, wherein the present invention will not release corrosive or irritating hydrogen halide gas, nor produce toxic carcinogens polybrominated benzoxins and polybrominated dibenzofurans, thereby avoiding the long-term impact of the material on the environment.
    Type: Grant
    Filed: September 20, 2022
    Date of Patent: April 30, 2024
    Assignees: SAFEKEY Engineering Technology (Zhengzhou), Ltd., Huizhou Mingsheng Chemical Materials Co., LTD., WELEAD Infrastructure Engineering Technology (Zhengzhou), Ltd.
    Inventors: Peng Zhao, Hongyuan Fang, Lei Wang, Chengchao Guo, Mingrui Du, Chao Zhang, Guobin Qiao