Abstract: A linker, comprising an Lb structure fragment, the Lb structure being selected from the following formula, wherein subscript q is selected from any integer from 1 to 20, preferably from 3 to 10, and most preferably from 5 to 8. The present application also relates to a use of the linker in the preparation of a linker-drug and a ligand-drug conjugate.

Abstract: A method of treating neurodegeneration and/or neurodegenerative condition, disease, or disorder caused by and/or associated with elevated or aberrant 15-PGDH activity in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.

Abstract: A 3DP preparation process of a high-strength rapid-dissolving magnesium alloy for an underground temporary plugging tool is disclosed by the present disclosure, comprising the following steps: 1) evenly mixing ingredients of material components; 2) importing the shape of a product needing to be printed into a computer control system, and printing alloy powder and glue in a 3D printer in an alternate spraying molding mode to obtain a blank with the needed shape; 3) drying the blank obtained in the step 2) and then carrying out degreasing and sintering in a protective atmosphere or vacuum; and 4) sintering the blank obtained in the step 3) at a high temperature of 570° C.-680° C. in the protective atmosphere or vacuum and then cooling to a room temperature.

Abstract: This application relates to a wireless apparatus, and in particular, to an apparatus that is capable of performing beam sweeping. The apparatus provided in embodiments of this application integrates a feed source that may transmit a wireless signal and a lens. The lens covers the feed source, and an inner surface and/or an outer surface of the lens are/is curved surfaces/a curved surface.

Abstract: This application relates to a wireless apparatus, and in particular, to an apparatus that is capable of performing beam sweeping. The apparatus provided in embodiments of this application integrates a feed source that may transmit a wireless signal and a lens. The lens covers the feed source, and an inner surface and/or an outer surface of the lens are/is curved surfaces/a curved surface.