Abstract: The present disclosure provides a risk assessment method of water inrush in tunnels constructed in water-rich grounds. The method includes the following steps: simulating a tunnel excavation process by finite element software MIDAS GTS NX and fluid-structure interaction; according to a research method of control variables, analyzing effects of a groundwater level, an elastic modulus and advanced pipe shed grouting on the stability of surrounding rock, and improving an algorithm of a radial basis function (RBF) neural network using a Grey Relation Analysis (GRA)-based Partitioning Around Medoid (PAM) clustering algorithm to assess risks of water inrush occurring in Qingdao area.

Abstract: A flexible electroluminescent fiber for embroidery sequentially includes: metal core wires, a light-emitting layer, a transparent conductive layer, a filament, and a protective paint, wherein a quantity of the metal core wires is an even number, and the metal core wires are pasted together before being wrapped by the light-emitting layer; the light-emitting layer is coated with the transparent conductive layer; the protective paint and the filament are exterior to the transparent conductive layer; the metal core wires emit light through energizing; a diameter of the electroluminescent fiber is 0.1-0.3 mm, and a 20-36V safe voltage is applied for emitting light. The flexible electroluminescent fiber of the present invention has sufficient tensile force, and smooth and soft surface. Appearance and hand feeling of the present invention are the same as those of clothing textile fibers.

Abstract: A method for trajectory generation based on player tracking is described herein. The method includes determining a temporal association for a first player in a captured field of view and determining a spatial association for the first player. The method also includes deriving a global player identification based on the temporal association and the spatial association and generating a trajectory based on the global player identification.

Abstract: Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.

Abstract: The present disclosure provides a method and a kit for detecting cell-free DNA (cfDNA) methylation, and belongs to the technical field of early cancer screening. The method includes the following steps: constructing and mixing a cfDNA library and a filter DNA to obtain a mixture of the cfDNA library and the filter DNA, co-immunoprecipitating the mixture with anti-5-methylcytosine (5mC) antibody, conducting methylation capture on methylated DNA fragments in the mixture, and purifying and eluting to obtain a captured product fragment; conducting amplification and enrichment, purification, recovery and screening to obtain a sequencing library; and sequencing on an Illumina sequencing platform, and bioinformatically analyzing acquired experimental data to know about the cfDNA methylation.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Provided herein, inter alia, are methods of treating cancer or cutaneous T-cell lymphoma (CTCL) using compounds of the invention.

Abstract: Described herein, inter alia, are IGF2BP2 inhibitor compounds and methods of using the same.

Abstract: Provided, inter alia, are methods and compositions for treating FTO-mediated cancer.

Abstract: The disclosure provides, inter alia, METTL16 inhibitors and methods of treating cancers that overexpress METTL16.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Disclosed are methods that create the perception for an audience that an actor is being transported from one location to another during a stage performance. Also disclosed are methods for entrance onto/exit from a stage platform by an actor, or entrance onto/exit from a stage backdrop by a precision image that represents an actor. The disclosed methods involve interaction of an actor with an object/prop or image of an object/prop, and/or involve interaction of an image of an actor with an object/prop or image of an object/prop during a stage performance.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Disclosed are methods that create the perception for an audience that an actor is being transported from one location to another during a stage performance. Also disclosed are methods for entrance onto/exit from a stage platform by an actor, or entrance onto/exit from a stage backdrop by a precision image that represents an actor. The disclosed methods involve interaction of an actor with an object/prop or image of an object/prop, and/or involve interaction of an image of an actor with an object/prop or image of an object/prop during a stage performance.

Abstract: A system for aggregation and organization of multimedia data acquired from a plurality of sources can include a data collection element, a multimedia segmentation element, a memory, an extraction element, and a user interface. The data collection element can be configured to receive multimedia data. The multimedia segmentation element can be coupled to the data collection element and can be configured to separate the multimedia data into a plurality of multimedia data segments. The memory can be configured to store hierarchical category information having a plurality of categories. The extraction element can be coupled to the multimedia segmentation element and the memory and can be configured to associate at least one of the plurality of categories with each of the plurality of multimedia data segments.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Disclosed herein, inter alia, are compositions and methods useful for treating liver diseases and metabolic diseases.