Patents by Inventor Hongzhi Xie

Hongzhi Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11913942
    Abstract: Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: February 27, 2024
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Murthy V S N Yerramilli, Hongzhi Xie, Daniel Wayne Patch, Giosi Farace
  • Patent number: 11422136
    Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: August 23, 2022
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Hongzhi Xie, Sreenivasa Rao Ramisetty, Murthy V S N Yerramilli
  • Publication number: 20220082501
    Abstract: The present invention relates to a method and reagents for determining the presence of or the amount of an analyte in a sample.
    Type: Application
    Filed: April 16, 2021
    Publication date: March 17, 2022
    Inventors: Jennifer E. Gagner, Kiamars Hajizadeh, Evan M. Peck, James R. Salter, Paul J. Travers, Christopher P. Turmel, Yingzi Wu, Hongzhi Xie, Murthy V.S.N. Yerramilli
  • Publication number: 20210018496
    Abstract: Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.
    Type: Application
    Filed: July 8, 2020
    Publication date: January 21, 2021
    Inventors: Murthy VSN Yerramilli, Hongzhi Xie, Daniel Wayne Patch, Giosi Farace
  • Patent number: 10775365
    Abstract: Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: September 15, 2020
    Assignee: IDEXX LABORATORIES, Inc.
    Inventors: Murthy V S N Yerramilli, Hongzhi Xie, Daniel Wayne Patch, Giosi Farace
  • Publication number: 20190120856
    Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.
    Type: Application
    Filed: October 19, 2018
    Publication date: April 25, 2019
    Inventors: Hongzhi Xie, Sreenivasa Rao Ramisetty, Murthy VSN Yerramilli
  • Publication number: 20160245801
    Abstract: Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 25, 2016
    Inventors: Murthy VSN Yerramilli, Hongzhi Xie, Daniel Wayne Patch, Giosi Farace
  • Patent number: 9255923
    Abstract: The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: February 9, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Harshini Mukundan, Hongzhi Xie, Basil I. Swanson, Jennifer Martinez, Wynne K. Grace
  • Publication number: 20140370532
    Abstract: The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.
    Type: Application
    Filed: June 27, 2014
    Publication date: December 18, 2014
    Inventors: Harshini Mukundan, Hongzhi Xie, Basil I. Swanson, Jennifer Martinez, Wynne K. Grace
  • Patent number: 8859268
    Abstract: The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: October 14, 2014
    Assignee: Los Alamos National Security, LLC
    Inventors: Harshini Mukundan, Hongzhi Xie, Basil I. Swanson, Jennifer Martinez, Wynne K. Grace
  • Publication number: 20110117585
    Abstract: The present invention addresses the simultaneous detection and quantitative measurement of multiple biomolecules, e.g., pathogen biomarkers through either a sandwich assay approach or a lipid insertion approach. The invention can further employ a multichannel, structure with multi-sensor elements per channel.
    Type: Application
    Filed: October 8, 2010
    Publication date: May 19, 2011
    Inventors: Harshini Mukundan, Hongzhi Xie, Basil I. Swanson, Jennifer Martinez, Wynne K. Grace