Patents by Inventor Hoong Yeet Yeang
Hoong Yeet Yeang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7994288Abstract: This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitising agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.Type: GrantFiled: July 15, 2009Date of Patent: August 9, 2011Assignees: The Board of the Rubber Research Institute of Malaysia, Universiti Sains MalaysiaInventors: Mary Jane Cardosa, Hamid Sharifah, Shirley Samuel-Verghese, Elumalai Sunderasan, Hoong Yeet Yeang, Hamzah Samsidar
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Publication number: 20110081349Abstract: The present invention relates to a protein found in natural rubber that can induce an allergic reaction in persons who have been sensitised to it. The invention provides for the process of isolating and purifying the protein and describes the characteristics of the protein, including its molecular weight, isoelectric point, amino acid sequence and allergenicity. The invention also describes the isolation and cloning a the DNA that encodes the protein. The production of the recombinant version of the protein using a protein expression vector is described.Type: ApplicationFiled: March 26, 2010Publication date: April 7, 2011Inventors: Siti Arija Mad Arif, Nyu Ping Chew, Hoong Yeet Yeang
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Patent number: 7732566Abstract: The present invention relates to a protein found in natural rubber that can induce an allergic reaction in persons who have been sensitised to it. The invention provides for the process of isolating and purifying the protein and describes the characteristics of the protein, including its molecular weight, isoelectric point, amino acid sequence and allergenicity. The invention also describes the isolation and cloning a the DNA that encodes the protein. The production of the recombinant version of the protein using a protein expression vector is described.Type: GrantFiled: December 11, 2007Date of Patent: June 8, 2010Assignee: Malaysian Rubber BoardInventors: Siti Arija Mad Ariff, Nyu Ping Chew, Hoong Yeet Yeang
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Publication number: 20090285859Abstract: This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitising agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.Type: ApplicationFiled: July 15, 2009Publication date: November 19, 2009Inventors: Mary Jane Cardosa, Hamid Sharifah, Shirley Samuel-Verghese, Elumalai Sunderasan, Hoong Yeet Yeang, Hamzah Samsidar
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Patent number: 7576184Abstract: This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitising agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.Type: GrantFiled: April 8, 2004Date of Patent: August 18, 2009Assignees: The Board of the Rubber Research Institute of Malaysia, Universiti Sains MalaysiaInventors: Mary Jane Cardosa, Hamid Sharifah, Shirley Samuel-Verghese, Elumalai Sunderasan, Hoong Yeet Yeang, Hamzah Samsidar
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Publication number: 20080292635Abstract: The present invention relates to a protein found in natural rubber that can induce an allergic reaction in persons who have been sensitised to it. The invention provides for the process of isolating and purifying the protein and describes the characteristics of the protein, including its molecular weight, isoelectric point, amino acid sequence and allergenicity. The invention also describes the isolation and cloning a the DNA that encodes the protein. The production of the recombinant version of the protein using a protein expression vector is described.Type: ApplicationFiled: December 11, 2007Publication date: November 27, 2008Applicant: MALAYSIAN RUBBER BOARDInventors: Siti Arija Mad Arif, Nyu Ping Chew, Hoong Yeet Yeang
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Patent number: 7329512Abstract: The present invention relates to a protein found in natural rubber that can induce an allergic reaction in persons who have been sensitised to it. The invention provides for the process of isolating and purifying the protein and describes the characteristics of the protein, including its molecular weight, isoelectric point, amino acid sequence and allergenicity. The invention also describes the isolation and cloning a the DNA that encodes the protein. The production of the recombinant version of the protein using a protein expression vector is described.Type: GrantFiled: February 27, 2004Date of Patent: February 12, 2008Assignee: Malaysian Rubber BoardInventors: Siti Arija Mad Arif, Nyu Ping Chew, Hoong Yeet Yeang
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Publication number: 20040171812Abstract: The present invention relates to a protein found in natural rubber that can induce an allergic reaction in persons who have been sensitised to it. The invention provides for the process of isolating and purifying the protein and describes the characteristics of the protein, including its molecular weight, isoelectric point, amino acid sequence and allergenicity. The invention also describes the isolation and cloning a the DNA that encodes the protein. The production of the recombinant version of the protein using a protein expression vector is described.Type: ApplicationFiled: February 27, 2004Publication date: September 2, 2004Applicant: MALAYSIAN RUBBER BOARDInventors: Siti Arija Mad Arif, Nyu Ping Chew, Hoong Yeet Yeang
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Patent number: 6759517Abstract: This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitizing agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.Type: GrantFiled: September 15, 1995Date of Patent: July 6, 2004Assignees: Universiti Sains Malaysia, The Board of the Rubber Research Institute of MalaysiaInventors: Mary Jane Cardosa, Hamid Sharifah, Shirley Samuel-Verghese, Elumalai Sunderasan, Hoong Yeet Yeang, Hamzah Samsidar