Patents by Inventor Hooshang Shahriari Zavareh

Hooshang Shahriari Zavareh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacture of single isomer methylphenidate
    Patent number: 7164025
    Abstract: The present invention pertains to a process for obtaining a single enantiomer, d or l, of threo-methylphenidate, comprising resolution of a mixture of the enantiomers; racemisation of the unwanted enantiomer, to give a mixture of all four stereoisomers; and separation of the erythro stereoisomers, to leave the same mixture of enantiomers for resolution.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: January 16, 2007
    Assignee: Celltech Pharma Europe Limited
    Inventors: Marianne Langston, Hooshang Shahriari Zavareh
  • Resolution of ritalinic acid salt
    Patent number: 6441178
    Abstract: A process for preparing an enantiomerically-enriched form of threo-ritalinic acid, which comprises resolving a mixture of enantiomers of a salt of the acid, said salt being formed with an achiral acid or base, using a chiral resolving agent. The resolved salt can be esterified, to give the therapeutic agent d-threo-methylphenidate.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: August 27, 2002
    Assignee: Medeva Europe Limited
    Inventors: Hooshang Shahriari Zavareh, Gerard Andrew Potter
  • Manufacture of single isomer methylphenidate
    Publication number: 20020032335
    Abstract: The present invention pertains to a process for obtaining a single enantiomer, d or l, of threo-methylphenidate, comprising resolution of a mixture of the enantiomers; racemisation of the unwanted enantiomer, to give a mixture of all four stereoisomers; and separation of the erythro stereoisomers, to leave the same mixture of enantiomers for resolution.
    Type: Application
    Filed: August 10, 2001
    Publication date: March 14, 2002
    Inventors: Marianne Langston, Hooshang Shahriari Zavareh
  • Resolution of ritalinic acid salt
    Publication number: 20020019535
    Abstract: A process for preparing an enantiomerically-enriched form of threo-ritalinic acid, which comprises resolving a mixture of enantiomers of a salt of the acid, said salt being formed with an achiral acid or base, using a chiral resolving agent. The resolved salt can be esterified, to give the therapeutic agent d-threo-methylphenidate.
    Type: Application
    Filed: January 19, 2000
    Publication date: February 14, 2002
    Inventors: Hooshang Shahriari Zavareh, Gerard Andrew Potter
  • Resolution of threo-methylphenidate
    Patent number: 6121453
    Abstract: A process for preparing substantially single enantiomer d-threo-methylphenidate, proceeds by means of a classical salt resolution using (-)-menthoxyacetic acid.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: September 19, 2000
    Assignee: Medeva Europe Limited
    Inventor: Hooshang Shahriari Zavareh
  • Process for preparing levobupivacaine and analogues thereof
    Patent number: 5777124
    Abstract: A process for preparing levobupivacaine, racemic bupivacaine or another N-alkyl analogue thereof, comprises chlorinating pipecolic acid hydrochloride, amidation of the resultant pipecolyl chloride hydrochloride in solvent, without isolation, with 2,6-dimethylaniline, and alkylation of the resultant pipecolic acid 2,6-xylidide. Alternatively, the alkylation may be followed by the amidation.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: July 7, 1998
    Assignee: Chiroscience Limited
    Inventors: Hooshang Shahriari Zavareh, Graham Anthony Charles Frampton