Patents by Inventor Horace Loh

Horace Loh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolidinone compounds and use thereof
    Patent number: 10544113
    Abstract: A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: January 28, 2020
    Assignees: National Health Research Institute, Regents of the University of Minnesota
    Inventors: Shau-Hua Ueng, Shiu-Hwa Yeh, Shu-Yu Lin, Chuan Shih, Horace Loh
  • Opioid receptor modulators and use thereof
    Patent number: 9827228
    Abstract: Disclosed is an in vitro screening method for identifying an antagonist-to-agonist allosteric modifier of a mu-opioid receptor and an in vivo method for confirming that a test compound is such a modifier of a mu-opioid receptor. Also disclosed is a method for treating an opioid receptor-associated condition using a compound of Formula (I) and a pharmaceutical composition containing the same.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: November 28, 2017
    Assignees: National Health Research Institutes, Regents of the University of Minnesota
    Inventors: Shau-Hua Ueng, Shiu-Hwa Yeh, Horace Loh, Yu-Sheng Chao
  • OPIOID RECEPTOR MODULATORS AND USE THEREOF
    Publication number: 20170056377
    Abstract: Disclosed is an in vitro screening method for identifying an antagonist-to-agonist allosteric modifier of a mu-opioid receptor and an in vivo method for confirming that a test compound is such a modifier of a mu-opioid receptor. Also disclosed is a method for treating an opioid receptor-associated condition using a compound of Formula (I) and a pharmaceutical composition containing the same.
    Type: Application
    Filed: July 12, 2016
    Publication date: March 2, 2017
    Inventors: Shau-Hua Ueng, Shiu-Hwa Yeh, Horace Loh, Yu-Sheng Chao