Patents by Inventor Horng H. Chen

Horng H. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin secreting polypeptides
    Patent number: 10336803
    Abstract: This document provides methods and materials related to insulin secreting polypeptides. For example, polypeptides having the ability to induce insulin secretion and methods and materials for using use such polypeptides to induce insulin secretion and to treat diabetes are provided.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: July 2, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • INSULIN SECRETING POLYPEPTIDES
    Publication number: 20180273600
    Abstract: This document provides methods and materials related to insulin secreting polypeptides. For example, polypeptides having the ability to induce insulin secretion and methods and materials for using use such polypeptides to induce insulin secretion and to treat diabetes are provided.
    Type: Application
    Filed: March 22, 2018
    Publication date: September 27, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, JR.
  • Insulin secreting polypeptides
    Patent number: 9938334
    Abstract: This document provides methods and materials related to insulin secreting polypeptides. For example, polypeptides having the ability to induce insulin secretion and methods and materials for using use such polypeptides to induce insulin secretion and to treat diabetes are provided.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: April 10, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • DIURETIC AND NATRIURETIC POLYPEPTIDES
    Publication number: 20160375103
    Abstract: This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: September 12, 2016
    Publication date: December 29, 2016
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, Jr., Horng H. Chen
  • Methods of treatment using natriuretic polypeptides
    Patent number: 9469682
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: October 18, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Methods of treatment of heart dysfunctions using diuretic and natriuretic polypeptides
    Patent number: 9439951
    Abstract: This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: September 13, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, Jr., Horng H. Chen
  • DIURETIC AND NATRIURETIC POLYPEPTIDES
    Publication number: 20150374793
    Abstract: This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: September 14, 2015
    Publication date: December 31, 2015
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, JR., Horng H. Chen
  • AQUARETIC AND NATRIURETIC POLYPEPTIDES LACKING VASODILATORY ACTIVITY
    Publication number: 20150376255
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 31, 2015
    Inventors: Horng H. Chen, John C. Burnett, JR.
  • INSULIN SECRETING POLYPEPTIDES
    Publication number: 20150368312
    Abstract: This document provides methods and materials related to insulin secreting polypeptides. For example, polypeptides having the ability to induce insulin secretion and methods and materials for using use such polypeptides to induce insulin secretion and to treat diabetes are provided.
    Type: Application
    Filed: February 13, 2014
    Publication date: December 24, 2015
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett
  • Method of treatment of renal dysfunctions with chimeric natriuretic peptides
    Patent number: 9132166
    Abstract: This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: September 15, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, Jr., Horng H. Chen
  • Chimeric aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 9102757
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: August 11, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Natriuretic polypeptides for reducing restenosis
    Patent number: 9079973
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: July 14, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Horng H. Chen, Ondrej Lisy
  • NATRIURETIC POLYPEPTIDE DELIVERY SYSTEMS
    Publication number: 20140357561
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Application
    Filed: July 24, 2014
    Publication date: December 4, 2014
    Inventors: Horng H. Chen, John C. Burnett, JR., Lim Soo Ghim, Subramanian K. Venkatraman
  • Natriuretic polypeptide delivery systems
    Patent number: 8835601
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: September 16, 2014
    Assignees: Mayo Foundation for Medical Education and Research, Nanyang Technological University
    Inventors: Horng H. Chen, John C. Burnett, Jr., Lim Soo Ghim, Subramanian S. Venkatraman
  • NATRIURETIC POLYPEPTIDE DELIVERY SYSTEMS
    Publication number: 20140179605
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Application
    Filed: March 7, 2013
    Publication date: June 26, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Horng H. Chen, John C. Burnett, JR.
  • SUBCUTANEOUS DELIVERY OF A LONG-ACTING NATRIURETIC PEPTIDE
    Publication number: 20140066367
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Application
    Filed: March 12, 2013
    Publication date: March 6, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Horng H. Chen, John C. Burnett, JR., Daniel J. McCormick
  • AQUARETIC AND NATRIURETIC POLYPEPTIDES LACKING VASODILATORY ACTIVITY
    Publication number: 20130296241
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: July 16, 2013
    Publication date: November 7, 2013
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • NATRIURETIC POLYPEPTIDES FOR REDUCING OR PREVENTING RESTENOSIS
    Publication number: 20130281375
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Application
    Filed: May 7, 2013
    Publication date: October 24, 2013
    Inventors: John C. Burnett, JR., Horng H. Chen, Ondrej Lisy
  • Chimeric aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 8530422
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: September 10, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Natriuretic polypeptides for reducing or preventing restenosis
    Patent number: 8455438
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: June 4, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Horng H. Chen, Ondrej Lisy