Patents by Inventor Horoyoshi Horikoshi

Horoyoshi Horikoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-(4-hydroxy-OR 4-acetoxy-benzyl)-3- triphenylmethylthiazolidine-2,4-dione and method for producing same
    Patent number: 5977374
    Abstract: A compound of the formula ##STR1## wherein R.sup.7 is a hydrogen atom or an acetyl group, and process for preparing said compounds.
    Type: Grant
    Filed: July 29, 1994
    Date of Patent: November 2, 1999
    Assignee: Sankyo Company, Limited
    Inventors: Takashi Fujita, Takao Yoshioka, Horoyoshi Horikoshi, Shinji Yoshioka
  • Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses
    Patent number: 5635534
    Abstract: Compounds of formula (I): ##STR1## (wherein: R.sup.0 is hydrogen, methyl or hydroxymethyl; R.sup.1 is substituted alkyl; R.sup.2 and R.sup.3 are each hydrogen, halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, alkyl, nitro, haloalkyl, or substituted alkyl; X is oxygen or sulfur; and Ar optionally substituted phenyl or naphthyl); and pharmaceutically acceptable salts thereof have a variety of valuable pharmaceutical activities, including anti-diabetic and anti-obesity activities; in addition, they are capable of treating or preventing hyperlipemia and hyperglycemia and, by inhibiting the action of aldose reductase, they can also be effective in the treatment and prevention of complications of diabetes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 3, 1997
    Assignee: Sankyo Company, Limited
    Inventors: Takashi Fujita, Takao Yoshioka, Horoyoshi Horikoshi, Shinji Yoshioka
  • Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses
    Patent number: 5576340
    Abstract: Compounds of formula (I): ##STR1## (wherein: R.sup.0 is hydrogen, methyl or hydroxymethyl; R.sup.1 is substituted alkyl; R.sup.2 and R.sup.3 are each hydrogen, halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, alkyl, nitro, haloalkyl, or substituted alkyl; X is oxygen or sulfur; and Ar optionally substituted phenyl or naphthyl); and pharmaceutically acceptable salts thereof have a variety of valuable pharmaceutical activities, including anti-diabetic and anti-obesity activities; in addition, they are capable of treating or preventing hyperlipemia and hyperglycemia and, by inhibiting the action of aldose reductase, they can also be effective in the treatment and prevention of complications of diabetes.
    Type: Grant
    Filed: January 26, 1995
    Date of Patent: November 19, 1996
    Assignee: Sankyo Company, Limited
    Inventors: Takashi Fujita, Takao Yoshioka, Horoyoshi Horikoshi, Shinji Yoshioka