Patents by Inventor Horst Neubauer

Horst Neubauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals
    Patent number: 5250524
    Abstract: The invention relates to bile acid derivatives of the formula IG1--X--G2 (I)in whichG1 and G2 are bile acid radicals or modified bile acid radicals in the form of the free acids, the esters or amides, the salt forms and also the forms derivatized on the alcohol groups andX is a bridge group or a single covalent bond, it being possible for G1 and G2 to be optionally bonded via X.The compounds according to the invention have a high affinity for the specific bile acid transport system of the small intestine and inhibit bile acid absorption in a concentration-dependent and competitive manner.
    Type: Grant
    Filed: December 4, 1991
    Date of Patent: October 5, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Kramer, Gunther Wess, Stefan Mullner, Horst Neubauer
  • Procedure for immunologic determination of procollagen peptide (type III) and procollagen peptide col 1 (type III) together and a process for preparing anti-procollagen peptide col 1 (type III) serum
    Patent number: 4504587
    Abstract: The antigens procollagen peptide (type (III) and procollagen peptide col 1 (type III) can be determined together immunologically by either(a) reacting a specified amount in each case of labeled procollagen peptide (type III) or procollagen peptide col 1 (type III) and a highly specific antiserum containing antibodies having affinity for both the antigens mentioned together with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), separating off the antigen-antibody complex formed and measuring the amount of labeling in the complex and/or in the supernatant, or(b) bringing a specified amount of the highly specific antiserum to reaction with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), fixing the unreacted amount of the antibody to procollagen peptide (type III) or procollagen peptide col 1 (type III) bound to a support, and bringing to reaction with a labeled second antibody, and th
    Type: Grant
    Filed: March 11, 1983
    Date of Patent: March 12, 1985
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rupert Timpl, Dietrich Brocks, Horst Neubauer, Helmut Strecker