Abstract: The present invention relates to novel substituted (&agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.

Abstract: The present invention relates to novel substituted &bgr;,&ggr;-fused lactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.

Abstract: The invention relates to polypeptides having the biological activity of latrotoxin receptors, and to nucleic acids encoding these polypeptides, and in particular to their use for finding active compounds for crop protection.

Abstract: The invention relates to cyclopentabenzofuran derivatives, processes for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of NF-&kgr;B-dependent diseases and medicaments which contain the cyclopentabenzofuran derivatives.

Abstract: The invention relates to polypeptides having the biological activity of peptide receptors, and to nucleic acids encoding these polypeptides, and in particular to their use for finding active compounds for crop protection.

Abstract: The present invention relates to novel substituted bicyclic lactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, cranial cerebral trauma, states of pain or CNS-mediated spasms.

Abstract: The present invention relates to the use of known efomycins and elaiophylins for the treatment of autoimmune disorders, to new natural substances efomycins M and T, and processes for their preparation; in particular to their use as medicaments in psoriasis therapy.

Abstract: The invention relates to cytostatics which, by modification with sugar, are tumor-specific. Suitable spacers ensure serum stability and at the same time an intracellular action.

Abstract: The present invention relates to the use of known efomycins and elaiophylins for the treatment of autoimmune disorders, to new natural substances efomycins M and T, and processes for their preparation; in particular to their use as medicaments in psoriasis therapy.

Abstract: Glass-fiber-reinforced ABS molding compounds containing up to 5% by weight of a tin-containing organic compound corresponding to formula (I) and/or (II) in which R1 and R2=C1-12 alkyl, R3, R4=C1-18 alkyl, R5=—(CH2)—n, —CH═CH—, —CH═CR1—, X=H, 1 equivalent of an alkali metal, preferably Na or K, ½ equivalent of an alkaline earth metal, preferably Mg or Ca, n=2-8.

Abstract: A roof arrangement includes a plurality of spaced apart substantially parallel adjacent battens arranged on increasing higher levels and a plurality of rows of roof slates supported on the battens. Each row of roof slates comprises a plurality of adjacently arranged slates with a gap being defined between two adjacent slates. Adjacent rows of slates are off-set. A support strip is located below the gap between two adjacent slates and extends laterally beyond the gap to a location underneath the two slates defining the gap, and further extends from one batten to a next higher batten. A waterproof strip extends below a row of slates from close to the lower end of the slates of the row of slates and is bent over the upper end of the slates of the row of slates to rest on to the upper end of the row of slates. First attachment elements pass through each slate near its upper end and through the waterproof strip below the slate into a batten located below the slate.

Abstract: According to the invention, a gutter for collecting and conveying water from a roof of a building includes an elongated channel having a rear wall for abutment against a fascia or other building member; a front wall spaced away from the rear wall land having an upper edge; a floor joining the rear wall and the front wall; and a coupling formation at the upper edge of the front wall for engagement with a bracket having an associated engagement formation, the bracket being attachable to a support structure, such as a rafter.

Abstract: The present invention relates to the targeted blocking of the genetic information of the viral messenger ribonucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haematopoietic cells with particularly suitable expression systems, which express a complementary "antisense RNA".

Abstract: Polycarbonate molding compositions resistant to light aging and exhibiting an improved notched impact strength are disclosed. The compositions which are based on an aromatic polycarbonate, aromatic polyester carbonate or a polyester, contain a redox-catalyzed graft polymer of resin-forming monomers on a rubber, a phosphorus compound and a fluorinated polyolefin.

Abstract: An electrochemical gas sensor for detecting gaseous components in the environment has a diffusion membrane, a measuring electrode, a counterelectrode, and, if desired, a reference electrode, pressed together in a disk stack, which are accommodated in a pot-shaped cover, which in turn is beaded around the sealing edge (6) of a housing pot (1). A compression spring (21) in the housing pot (1) presses a wick disk (20) against the measuring electrode (12), so that a constant and pressurized, intimate and sealed positioning of the disk stack is guaranteed. It is achieved as a result that no additional contact leads from the electrodes to the outer space of the sensor to the measuring and evaluating unit are needed, so that leakage-free sealing of the sensor to the outside is possible, and that a constantly stable, reproducible measured signal is obtained because of the defined and narrow electrolyte film on the surface of the measuring electrode.

Abstract: A flame resistant molding composition containing a polycarbonate resin, a graft polymer and, as a flame retarding agent a phosphoric acid ester of novolak in combination with an anti drip agent is disclosed. The composition may further contain a thermoplastic copolymer and/or polyalkylene terephthalate. A process for the preparation of the composition is also disclosed.

Abstract: Thermoplastic moulding compounds based on fully aromatic polyester carbonates polyalkylene terephthalates and grafted diene rubber have a well balanced combination of notched impact strength at room temperature and low temperatures and high weld line strength and may be used for the production of moulded articles, in particular by injection moulding.

Abstract: The invention relates to thermoplastic molding compounds containing thermoplastic aromatic polycarbonates, thermoplastic copolymers, optionally graft polymers and/or tetrafluoroethylene polymers and/or silicone resins, characterized in that they contain phosphorus compounds corresponding to formula (I) ##STR1## in which R is a --CH.sub.2 --, ##STR2## group and the aromatic radicals may even be alkyl-substituted.

Abstract: A motor-vehicle lamp having a light-transmissive shield (3) which is attached to a grounding plate (4) by a holding device (8) and which defines an opening (6) suitable for water removal includes an electrically conductive pin (1) for protecting the motor-vehicle lamp from destruction due to a lightning strike, the pin having a first end extending into the opening (6) and a second end making electrically-conductive contact with an electrical ground (10, 10') of the motor vehicle.

Abstract: The invention relates to polycarbonate molding compounds consisting of halogen-free polycarbonates, graft polymers, phosphorus compounds, tetrafluoroethylene polymers and, optionally, copolymers and/or, optionally, other additives known per se and a process for their production.