Abstract: The invention relates to a migration device (100) having a sample chamber (102), a migration matrix (105) arranged in the sample chamber (102), and a fluid outlet (103). The migration device (100) also has a discharge structure (104), which is designed to discharge fluids from the sample chamber (102) to the fluid outlet (103). The invention also relates to methods for operating the migration device and to the use of a migration device for determining the migration ability of ameboidally mobile cells.

Abstract: The invention relates to a migration device (100) having a sample chamber (102), a migration matrix (105) arranged in the sample chamber (102), and a fluid outlet (103). The migration device (100) also has a discharge structure (104), which is designed to discharge fluids from the sample chamber (102) to the fluid outlet (103). The invention also relates to methods for operating the migration device and to the use of a migration device for determining the migration ability of ameboidally mobile cells.

Abstract: The present invention relates to a method of diagnosing an existing or developing acute pneumonia induced by a microorganism by detecting one or more volatile organic compound(s) in a subject's sample and the use of one or more volatile organic compound(s) for the detection of Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae or Haemophilus influenza and optionally opportunistic pathogen Candida albicans.

Abstract: A method for monitoring the use of a consumable in a disposable design in multiple analyzers is disclosed. The method provides a disposable consumable; uses the consumable as intended during operation of the first analyzer; and collects usage-relevant information for the consumable concerning the intended use of the consumable during operation of the first analyzer. Usage-relevant data derived from the usage-relevant information is stored in a memory unit assigned to the consumable. The consumable may be removed and again provided in the first or second analyzer. The first or second analyzer partially reads the usage-relevant data from the memory unit, evaluates the usage-relevant data, and derives control signals concerning the permissibility and/or type of a further intended use of the consumable during operation of the analyzer as a reaction to the evaluation of the read usage-relevant data.

Abstract: A method and an apparatus for accelerating the equilibration of a fluid, typically the reference fluid of an analyzer, are provided, the surface of the fluid being in contact with a gas phase. The device can include a cassette, which can be exchangeably inserted into an analyzer and which holds at least one flexible, gas-tight bag, in which the fluid and the gas phase are accommodated. The cassette or the analyzer can include at least one transmitting element, which can be caused to vibrate and which mechanically contacts the flexible bag in order to input mechanical energy into the liquid in at least one wall region.

Abstract: A method and an apparatus for accelerating the equilibration of a fluid, typically the reference fluid of an analyzer, are provided, the surface of the fluid being in contact with a gas phase. The device can comprise a cassette, which can be exchangeably inserted into an analyzer and which holds at least one flexible, gas-tight bag, in which the fluid and the gas phase are accommodated. The cassette or the analyzer can include at least one transmitting element, which can be caused to vibrate and which mechanically contacts the flexible bag in order to input mechanical energy into the liquid in at least one wall region.

Abstract: The present invention relates to a method of diagnosing an existing or developing acute pneumonia induced by a microorganism by detecting one or more volatile organic compound(s) in a subject's sample and the use of one or more volatile organic compound(s) for the detection of Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae or Haemophilus influenza and optionally opportunistic pathogen Candida albicans.

Abstract: The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO2, and pO2, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Abstract: The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO2, and pO2, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Abstract: A method for monitoring the use of a consumable in a disposable design in one or more analyzers which are each configured to analyze one or more liquids, in particular body fluids, is provided where the method comprises the following steps: providing a disposable consumable in a first analyzer; using the disposable consumable as intended during operation of the first analyzer; collecting usage relevant information for the disposable consumable which concern the intended use of the disposable consumable during operation of the first analyzer; storing usage-relevant data which are derived from the usage-relevant information in a memory unit assigned to the disposable consumable; removing the disposable consumable from the first analyzer; again providing the disposable consumable in the first analyzer or in a second analyzer, at least partially reading the usage-relevant data from the memory unit in the first or the second analyzer; evaluating the usage-relevant data that have been read out by a control device;

Abstract: The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO2, and pO2, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Abstract: The invention relates to a sample entry device for delivering medical samples, preferably blood samples, from diverse sample containers to an analyzer, wherein sample transfer between sample intake and measuring cells of the analyzer taking place via gas-tight sample lines. According to the invention a fixed intake needle is provided at the entry side of the analyzer, which includes an elastic intake element that is axially slideable on the intake needle and has a conical intake opening. In addition, a holding element is provided, which is axially slideable parallel to the intake needle and can be shifted relative to the intake element. In a first position the holding element exposes the intake element and in a second position places a conical opening above the intake element to accommodate a syringe.

Abstract: The invention relates to a method for determining the current filling level of a liquid, preferably a calibrating, quality control, or cleaning fluid, or waste water, in a container, for example of an analyzer, where an immersion pipe is dipped into the liquid in the container to be filled or drained. The immersion pipe is connected to a pumping device via a tube system. The pressure p in the tube system is measured and increased, starting from the ambient pressure p0, until a first discontinuous pressure change occurs at pressure p1 due to the liquid column in the immersion pipe being forced out of the pipe, and/or the pressure p in the tube system is decreased until the liquid column in the immersion pipe reaches a change in cross-section of the immersion pipe, which change is situated above the maximum filling level of the liquid, such that a second discontinuous pressure change occurs at pressure p2 due to the liquid column reaching the change in cross-section.

Abstract: The invention relates to a method for determining the current filling level of a liquid, preferably a calibrating, quality control, or cleaning fluid, or waste water, in a container, for example of an analyzer, where an immersion pipe is dipped into the liquid in the container to be filled or drained. The immersion pipe is connected to a pumping device via a tube system. The pressure p in the tube system is measured and increased, starting from the ambient pressure p0, until a first discontinuous pressure change occurs at pressure p1 due to the liquid column in the immersion pipe being forced out of the pipe, and/or the pressure p in the tube system is decreased until the liquid column in the immersion pipe reaches a change in cross-section of the immersion pipe, which change is situated above the maximum filling level of the liquid, such that a second discontinuous pressure change occurs at pressure p2 due to the liquid column reaching the change in cross-section.

Abstract: The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO2, and pO2, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Abstract: In order to improve the shelflife of tonometered fluids containing at least one dissolved gas component and being packaged in a flexible container, a gas phase containing at least the dissolved gas component of the fluid is additionally introduced into the flexible container. The volume of the tonometered fluid and the volume of the gas phase together amounting to less than the maximum filling volume of the flexible container, which is collapsed when it is empty but unfolding when it is being filled.