Abstract: An inhaler with a protective device for protecting the inhaler against removal or replacement of the cartridge, having a readiness indicator for displaying a not-ready-to-trigger state or a ready-to-trigger state, and a breath indicator. Also, an inhaler with an insert for putting the inhaler into a ready-to-trigger state and/or for breaking a tamper-proof seal.

Abstract: A machine and a method for drilling a hole or setting a screw is provided, wherein the machine comprises a motor having a shaft and one or more magnetic coils, providing electric current to the one or more magnetic coils to rotationally drive the shaft, and switching the electric current at a commutation frequency to define a rotational speed of the shaft. A signal may be generated when a force towards the machine applied to the shaft increases and/or a torque applied to the shaft increases and the rotational speed of the motor may be increased to a first rotational speed when the signal is received. The rotational speed may be at least 6,800 RPM and at most 8,500 RPM.

Abstract: The present invention relates to An intact whole IgG bispecific antibody, comprising the following properties: a) binding to a T cell; b) binding to a tumor-associated antigen on a tumor cell; c) the affinity of said bispecific antibody to the tumor-associated antigen is in a range of KD=10?5-10?8 M.

Abstract: The fan housing for a multistage fan has a first housing part for receiving the electric motor, a second housing part mounted coaxially on the first housing part, and a housing cover mounted on the opposing side of the second housing part. So that fan noise is minimize during fan operation, for improved protection from external effects and to avoid tension originating from thermal expansion in the blower housing the housing cover for the second housing part has a peripheral cover edge portion and is pot-shaped or cap-shaped; the housing cover completely overlaps the second housing part; an overlapping peripheral portion of this housing cover has a radial spacing from the second housing part so as to form an air cushion between the second housing part and the housing cover and the cover edge portion of the housing cover is supported on the first housing part so as to enclose the second housing part.